AI-Powered Synthetic Biology: Current Situation, Challenges, and Future Perspectives
By: Izem Olcay Sahin, Nuriye Gokce, Duygu T. Yildirim, A. Baki Yildirim, Hilal Akalın, Donald Martin, Tommaso Beccari, Oscar Vicente, Iza Radecka, Fideline Tchuenbou-Magaia, Robert S. Marks, Ratnesh Lal, Satya Prakash, Adam Mechler, Mario Petrov Milkov, Svetlana Fotkova Georgieva, Ilia Iliev, Kosi Gramatikoff, Ed Judge, Milica Markovic, Radka Kaneva, Galina Aleksieva Yaneva, Nadya Vasileva Agova, Nikoleta Dobromirova Ivanova, Mariya Kiryakova Tsvetkova, Ivelin Rosenov Iliev, Michel Salzet, Kisung Ko, Michele Maffia, Chiara Coppola, Matteo Bertelli, Isabelle Fournier, Lejla Pojskic, Qun Sun, Lembit Nei, Reynir Armgrisson, Gary Henehan, Daumantas Matulis, Dijana Plaseska-Karanfilska, K. Santacruz-Gomez, Isabel Belo, Štefánia Hrončeková, Sehime G. Temel, Ole K. Greiner-Tollersrud, Dana Tapaloaga, Andreas Janecke, Ivana Marova, Benedetta Spedicato, Polona Žnidaršič-Plazl, Igor Plazl, Ariola Bacu, Anargyros N. Moulas, Alexander Kilchevsky, M. Sait Dundar, P. Bartolini, Anita Slavica, Francisco Fuentes, Jose Carlos Lorenzo Feijoo, Andrés Izquierdo Romero, Helal Ragab Moussa, Amin Hejazi, Attya Bhatti, Bajram Berisha, Alma Kokhmetova, Nikolai Zhelev, Juraj Krajcovic, Viktor Nedovic, Alla Salmina, Mark Nujiten, İrem Kalay, Majeti Narasimha Vara Prasad, Luis Izquierdo Lopez, Dominika Vešelényiová, Maria Rachele Ceccarini, Bernard Fioretti, Gergana P. Ilieva, M. Cerkez Ergoren, Noursaid Tligui, Serghei Sprincean, Saharuddin Bin Mohamad, Miklos Kellermayer, Esra Arslan Ates, Pembe Savas, Ivana Márová, Martin Koller, Hakan Gurkan, Erhan Parıltay, Ercument Ovalı, Sevda Yesim Ozdemir, Tanil Kocagoz, Hilmi Tozkir, Gunnur Demircan, Eda Tahir Turanli, Havva Cobanogullari, Victor Nedovic, Victor Revin, Recep Eroz, Annika Joy Meitern and Munis Dundar
Authors
Izem Olcay Sahin
Department of Medical Genetics, School of Medicine, Erciyes University, Kayseri, Türkiye
Nuriye Gokce
Department of Medical Genetics, School of Medicine, Erciyes University, Kayseri, Türkiye
Duygu T. Yildirim
Department of Medical Genetics, School of Medicine, Erciyes University, Kayseri, Türkiye
A. Baki Yildirim
Department of Medical Genetics, School of Medicine, Erciyes University, Kayseri, Türkiye
Hilal Akalın
Department of Medical Genetics, School of Medicine, Erciyes University, Kayseri, Türkiye
Donald Martin
Université Grenoble Alpes, Grenoble, France
Tommaso Beccari
Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy
Oscar Vicente
Institute for the Conservation and Improvement of Valencian Agrodiversity (COMAV), Universitat Politècnica de València, Valencia, Spain
Iza Radecka
School of Pharmacy and Life Sciences, Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton, UK
Fideline Tchuenbou-Magaia
School of Pharmacy and Life Sciences, Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton, UK
Robert S. Marks
Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beersheba, Israel
Ratnesh Lal
Neuroscience Research Institute, University of California, Santa Barbara, USA
Satya Prakash
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada
Adam Mechler
Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Australia
Mario Petrov Milkov
Department of Dental Material Science and Prosthetic Dental Medicine, Faculty of Dental Medicine, Varna, Bulgaria
Svetlana Fotkova Georgieva
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Varna, Varna, Bulgaria
Ilia Iliev
Department of Biochemistry and Microbiology, Faculty of Biology, University of Plovdiv, Plovdiv, Bulgaria
Kosi Gramatikoff
Research Institute, Varna, Bulgaria
Ed Judge
EPAM Systems Ltd, London, UK
Milica Markovic
University Hospital Basel, Clinical Trial Unit, Basel
Radka Kaneva
Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University, Sofia, Bulgaria
Galina Aleksieva Yaneva
Department of Biology, Faculty of Pharmacy, Medical University of Varna, Varna, Bulgaria
Nadya Vasileva Agova
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Varna, Varna, Bulgaria
Nikoleta Dobromirova Ivanova
Department of Biology, Faculty of Pharmacy, Medical University of Varna, Varna, Bulgaria
Mariya Kiryakova Tsvetkova
Department of Biology, Faculty of Pharmacy, Medical University of Varna, Varna, Bulgaria
Ivelin Rosenov Iliev
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Varna, Varna, Bulgaria
Michel Salzet
Réponse Inflammatoire et Spectrométrie de Masse - PRISM, University of Lille, Lille, France
Kisung Ko
Department of Medicine, College of Medicine, Chung-Ang University, Seoul, Korea
Michele Maffia
Department of Experimental Medicine, University of Salento, Lecce, Italy
Chiara Coppola
Department of Experimental Medicine, University of Salento, Lecce, Italy
Matteo Bertelli
MAGI’S LAB, Rovereto, Italy
Isabelle Fournier
Réponse Inflammatoire et Spectrométrie de Masse-PRISM, University of Lille, Lille, France
Lejla Pojskic
Institute for Genetic Engineering and Biotechnology, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
Qun Sun
College of Life Sciences, Sichuan University, Chengdu, China
Lembit Nei
School of Engineering, Tallinn University of Technology, Tartu College, Tartu, Estonia
Reynir Armgrisson
Iceland Faculty of Medicine, Division of Life Science, University of Iceland, Reykjavik
Gary Henehan
School of Food Science and Environmental Health, Technological University of Dublin, Dublin, Ireland
Daumantas Matulis
Department of Biothermodynamics and Drug Design, Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania
Dijana Plaseska-Karanfilska
Research Centre for Genetic Engineering and Biotechnology “Georgi D. Efremov”, Macedonian Academy of Sciences and Arts, Skopje, Macedonia
K. Santacruz-Gomez
Physics Department, University of Sonora, Col. Centro, Hermosillo, Mexico
Isabel Belo
Centre of Biological Engineering, University of Minho, Braga, Portugal
Štefánia Hrončeková
Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia
Sehime G. Temel
Department of Translational Medicine, Institute of Health Sciences, Bursa Uludag University
Department of Medical Genetics, Bursa Uludag University Faculty of Medicine
Department of Histology and Embryology, Faculty of Medicine, Bursa Uludag University, Bursa, Turkey
Ole K. Greiner-Tollersrud
Institute of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway
Dana Tapaloaga
Faculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Bucharest, Romania
Andreas Janecke
Department of Paediatrics I, Medical University of Innsbruck, Innsbruck, Austria
Division of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria
Ivana Marova
Department of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Brno, Czech Republic
Benedetta Spedicato
Lab of Clinical Proteomics, Italy
Polona Žnidaršič-Plazl
Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia
Igor Plazl
Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia
Ariola Bacu
Molecular Biotechnology Department of Biotechnology, Faculty of Natural Sciences, University of Tirana, Tirana, Albania
Anargyros N. Moulas
General Department, University of Thessaly, Larisa, Greece
Alexander Kilchevsky
Laboratory of Ecological Genetics and Biotechnology, The National Academy of Sciences of Belarus, Minsk, Belarus
M. Sait Dundar
Department of Medical Imaging Techniques, Halil Bayraktar Vocational School, Erciyes University, Kayseri, Turkiye
P. Bartolini
European Laboratory for Non-Linear Spectroscopy (LENS), Universitá degli Studi di Firenze, Sesto Fiorentino, Italy
Anita Slavica
University of Zagreb Faculty of Food Technology and Biotechnology, Zagreb, Croatia
Francisco Fuentes
Pontificia Universidad Católica de Chile, Facultad de Agronomía e Ingeniería Molecular genetics, Santiago, Chile
Jose Carlos Lorenzo Feijoo
Department for Plant Breeding and Conservation of Genetic Resources, Bioplant Center, University of Ciego de Ávila Máximo Gómez Báez, Ciego de Avila, Cuba
Andrés Izquierdo Romero
Departamento de Ciencias de la Vida y la Agricultura, Universidad de las Fuerzas Armadas ESPE, Sangolquí, Ecuador
Grupo de Investigación en Microbiología y Ambiente GIMA, Universidad de las Fuerzas Armadas, Sangolquí, Ecuador
Centro de Nanociencia y Nanotecnología CENCINAT, Universidad de las Fuerzas Armadas, Sangolquí, Ecuador
Helal Ragab Moussa
Radioisotope Department, Nuclear Research Center Atomic Energy Authority, Egypt
Amin Hejazi
Department of Food Biotechnology, Agricultural Biotechnology Research Institute of Iran (ABRII), Tabriz, Iran
Attya Bhatti
Department of Biomedicine, Atta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), Islamabad, Pakistan
Bajram Berisha
Animal Biotechnology, Faculty of Agriculture and Veterinary, University of Prishtina Prishtinë, Kosovo
Chair of Animal Physiology and Immunology, TUM School of Life Sciences, Munich, Germany
Academy of Science of Albania, Tirana, Albania
Alma Kokhmetova
Department of Genetics and Breeding, Institute of Plant Biology and Biotechnology, Almaty, Kazakhstan
Nikolai Zhelev
School of Medicine, University of Dundee, Scotland, UK
Medical University, Plovdiv, Bulgaria
Juraj Krajcovic
Institute of Biology and Biotechnology, Faculty of Natural Sciences, University of Ss. Cyril and Methodius, Trnava, Slovakia
Viktor Nedovic
University of Belgrade, Faculty of Agriculture, Belgrade, Serbia
Alla Salmina
Laboratory of Neurobiology and Tissue Engineering, Russian Center of Neurology and Neurosciences, Moscow, Russia
Mark Nujiten
A2M, Health Economics and Valuation, The Netherlands
Department of Biotechnology Engineering, Ben-Gurion University, Beersheba, Israel
İrem Kalay
Department of Medical Genetics, University of Health Sciences Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey
Majeti Narasimha Vara Prasad
Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Hyderabad, India
Luis Izquierdo Lopez
Veritas Intercontinental, Madrid, Spain
Dominika Vešelényiová
Institute of Biology and Biotechnology, Faculty of Natural Sciences, University of Ss. Cyril and Methodius, Trnava, Slovakia
Maria Rachele Ceccarini
Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy
C.I.B., Trieste, Italy
Bernard Fioretti
Department of Chemistry, Biology and Biotechnologies, University of Perugia, Perugia, Italy
Gergana P. Ilieva
University of Chemical Technology and Metallurgy, Faculty of Chemical Technology, Sofia, Bulgaria
M. Cerkez Ergoren
Department of Medical Genetics, Near East University Faculty of Medicine, Nicosia, Cyprus
Noursaid Tligui
Pathology and Veterinary Public Health Department, Institut Agronomique et Vététinaire HASSAN II, Rabat, Morocco
Serghei Sprincean
Institute of Legal, Political and Sociological Research, State University of Moldova, Chișinău, Moldova
Saharuddin Bin Mohamad
Bioinformatics Programme, Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia
Miklos Kellermayer
Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary
Esra Arslan Ates
Department of Medical Genetics, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye
Pembe Savas
East Mediterranean University, Department of Biological Sciences, Famagusta, Cyprus
Ivana Márová
Department of Biomedical Sciences, Università Degli Studi di Sassari, Sassari, Italy
Martin Koller
Institute of Chemistry, University of Graz, NAWI Graz, Austria
Hakan Gurkan
Trakya Üniversitesi Tıp Fakültesi, Edirne, Türkiye
Erhan Parıltay
Department of Medical Genetics, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye
Ercument Ovalı
Acibadem Labcell Cellular Therapy Laboratory, Istanbul, Turkey
Sevda Yesim Ozdemir
Department of Medical Genetics, Uskudar University Faculty of Medicine, Istanbul, Turkey
Tanil Kocagoz
Department of Medical Microbiology, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Türkiye
Department of Medical Biotechnology, Graduate School of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Türkiye
Hilmi Tozkir
Department of Medical Genetics, Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey
Gunnur Demircan
Department of Medical Biology and Genetics, Demiroglu Bilim University, Istanbul, Turkey
Eda Tahir Turanli
Department of Molecular Biology and Genetics, Graduate School of Natural and Applied Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Türkiye
Department of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Türkiye
Havva Cobanogullari
East Mediterranean University, Department of Biological Sciences, Famagusta, Cyprus
Victor Nedovic
University of Belgrade, Faculty of Agriculture, Nemanjina, Serbia
Victor Revin
Department of Biotechnology and Biochemistry, Ogarev Mordovia State University, Saransk, Russia
Recep Eroz
Aksaray University Medical School, Department of Medical Genetics, Aksaray, Turkey
Annika Joy Meitern
School of Engineering, Tallinn University of Technology, Tartu College, Tartu, Estonia
Munis Dundar
Department of Medical Genetics, School of Medicine, Erciyes University, Kayseri, Türkiye
DOI: https://doi.org/10.2478/ebtj-2026-0015 | Journal eISSN: 2564-615X
Language: English
Page range: 193 - 225
Published on: Jul 23, 2026
Published by: European Biotechnology Thematic Network Association
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
Related subjects:
© 2026 Izem Olcay Sahin, Nuriye Gokce, Duygu T. Yildirim, A. Baki Yildirim, Hilal Akalın, Donald Martin, Tommaso Beccari, Oscar Vicente, Iza Radecka, Fideline Tchuenbou-Magaia, Robert S. Marks, Ratnesh Lal, Satya Prakash, Adam Mechler, Mario Petrov Milkov, Svetlana Fotkova Georgieva, Ilia Iliev, Kosi Gramatikoff, Ed Judge, Milica Markovic, Radka Kaneva, Galina Aleksieva Yaneva, Nadya Vasileva Agova, Nikoleta Dobromirova Ivanova, Mariya Kiryakova Tsvetkova, Ivelin Rosenov Iliev, Michel Salzet, Kisung Ko, Michele Maffia, Chiara Coppola, Matteo Bertelli, Isabelle Fournier, Lejla Pojskic, Qun Sun, Lembit Nei, Reynir Armgrisson, Gary Henehan, Daumantas Matulis, Dijana Plaseska-Karanfilska, K. Santacruz-Gomez, Isabel Belo, Štefánia Hrončeková, Sehime G. Temel, Ole K. Greiner-Tollersrud, Dana Tapaloaga, Andreas Janecke, Ivana Marova, Benedetta Spedicato, Polona Žnidaršič-Plazl, Igor Plazl, Ariola Bacu, Anargyros N. Moulas, Alexander Kilchevsky, M. Sait Dundar, P. Bartolini, Anita Slavica, Francisco Fuentes, Jose Carlos Lorenzo Feijoo, Andrés Izquierdo Romero, Helal Ragab Moussa, Amin Hejazi, Attya Bhatti, Bajram Berisha, Alma Kokhmetova, Nikolai Zhelev, Juraj Krajcovic, Viktor Nedovic, Alla Salmina, Mark Nujiten, İrem Kalay, Majeti Narasimha Vara Prasad, Luis Izquierdo Lopez, Dominika Vešelényiová, Maria Rachele Ceccarini, Bernard Fioretti, Gergana P. Ilieva, M. Cerkez Ergoren, Noursaid Tligui, Serghei Sprincean, Saharuddin Bin Mohamad, Miklos Kellermayer, Esra Arslan Ates, Pembe Savas, Ivana Márová, Martin Koller, Hakan Gurkan, Erhan Parıltay, Ercument Ovalı, Sevda Yesim Ozdemir, Tanil Kocagoz, Hilmi Tozkir, Gunnur Demircan, Eda Tahir Turanli, Havva Cobanogullari, Victor Nedovic, Victor Revin, Recep Eroz, Annika Joy Meitern, Munis Dundar, published by European Biotechnology Thematic Network Association
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