Integrated Biotechnological Strategies for Planetary Health and Ecosystem Restoration
Abstract
The escalation of ecological degradation, marked by climatic instability, precipitous biodiversity loss, and systemic chemical infiltration, necessitates a shift toward integrated biotechnological intervention. This analysis considers how the trajectory of diverse advanced methodologies, including environmental DNA (eDNA) surveillance, CRISPR-based genetic restitution, and synthetic biology-driven bioremediation, might be synthesized into a unified Planetary Health Framework. By exploring the convergence of high-precision genomic engineering, AI-augmented bioinformatic modeling, and the tenets of a circular bio-economy, we examine the capacity of technological intervention to ameliorate ecological stressors and restore critical ecosystems.
Moving beyond the constraints of conventional conservation, this discourse explores frontier solutions in climate-resilient agrotechnology, photo-driven biomanufacturing, and technologically integrated urban ecology, highlighting the criticality of microbiome modulation and comprehensive genomic repositories in stabilizing the biosphere. By reconciling molecular-level precision with macro-scale systems ecology, this framework points to a trajectory for sustainable development where technological scalability is constrained by, yet optimized for, planetary boundaries. Ultimately, this review addresses the imperatives of ethical oversight and highlights the multi-sectoral governance architectures required for the responsible global deployment of these “living technologies.”
© 2026 Duygu T. Yildirim, A. Baki Yildirim, Donald Martin, Tommaso Beccari, Oscar Vicente, Iza Radecka, Fideline Tchuenbou-Magaia, Robert Marks, Ratnesh Lal, Satya Prakash, Adam Mechler, Mario Petrov Milkov, Svetlana Fotkova Georgieva, Ilia Iliev, Radka Kaneva, Nuriye Gokce, Galina Aleksieva Yaneva, Nadya Vasileva Agova, Nikoleta Dobromirova Ivanova, Izem Olcay Sahin, Mariya Kiryakova Tsvetkova, Ivelin Rosenov Iliev, Michel Salzet, Kisung Ko, Michele Maffia, Matteo Bertelli, Isabelle Fournier, Lejla Pojskic, Qun Sun, Lembit Nei, Reynir Armgrisson, Gary Henehan, Daumantas Matulis, Dijana Plaseska-Karanfilska, Karla Santacruz-Gomez, Isabel Belo, Havva Cobanogullari, Mahmut Çerkez Er-goren, Sehime G. Temel, Anna Zajakina, Ole K. Greiner-Tollersrud, Dana Tapaloaga, Andreas Janecke, Esra Arslan Ates, Ivana Marova, Benedetta Spedicato, Polona Žnidaršič-Plazl, Igor Plazl, Ariola Bacu, Anargyros N Moulas, Alexander Kilchevsky, P. Bartolini, M. Sait Dundar, Anita Slavica, Francisco Fuentes, Jose Carlos Lorenzo Feijoo, Andrés Izquierdo Romero, Helal Ragab Moussa, Amin Hejazi, Attya Bhatti, Bajram Berisha, Alma Kokhmetova, Nikolai Zhelev, Juraj Krajcovic, Dominika Vešelényiová, Irem Kalay, Viktor Nedovic, Alla Salmina, Mark Nujiten, Victor Revin, Luis Izquierdo López, Hilal Akalin, Munis Dundar, published by European Biotechnology Thematic Network Association
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