Have a personal or library account? Click to login
Inhibitory effects of agmatine on monoamine oxidase (MAO) activity: Reconciling the discrepancies Cover

Inhibitory effects of agmatine on monoamine oxidase (MAO) activity: Reconciling the discrepancies

Open Access
|Apr 2018

References

  1. Raacsh W, Schafer U, Chun J & Dominiak P. Biological significance of agmatine, an endogenous ligand at imidazoline binding sites. Br J Pharmacol. 2001; 133, 755-780.10.1038/sj.bjp.070415311454649
  2. Aricioglu-kartal F & Uzbay IT. Inhibitory effect of agmatine on naloxone-precipitated abstinence syndrome in morphine dependent rats. Life Sci.1997; 61, 1775-1881.10.1016/S0024-3205(97)00801-19365224
  3. Regunathan S, Youngson C, RaascH W, Wang H & Reis DJ. Imidazoline receptors and agmatine in blood vessels: a novel system inhibiting vascular smooth muscle proliferation. J Pharmacol Exp Ther. 1996; 276, 1272-1282.8786560
  4. Gilad GM, Gilad VH & Rabey JM. Arginine and ornithine decarboxylation in rodent brain: coincidental changes during development and after ischemia. Neurosi Lett 1996; 216, 33-36.10.1016/0304-3940(96)12996-7
  5. Olmos G, Degregorio-Rocasolano N, Paz RM, Gasull T, Assumpcio BM, Trullas R, Villarroel A, Lerma J & Garcia-Sevilla JA. Protection by imidazol(ine) drugs and agmatine of glutamate-induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor. Br J Pharmacol. 1999; 127,1317-1326.1045528110.1038/sj.bjp.0702679
  6. Reis DJ & Regunathan S. Is agmatine a novel neurotransmitter in brain? TiPS. 2000; 21, 187-193.
  7. Goracke-Postle CJ, Overland AC, Riedl MS, Stone LS, Fairbanks CA. Potassium-and capsaicin-induced release of agmatine from spinal nerve terminals. J. Neurochem. 2007 Sep;102(6):1738-48.10.1111/j.1471-4159.2007.04647.x17539920
  8. Li G, Regunathan S, Barrow CJ, Eshraghi J, Cooper R, & Reis DJ. Agmatine: an endogenous clonidine-displacing substance in the brain. Science. 1994; 263:966-9.10.1126/science.79060557906055
  9. Tesson F, Prip-Buus C, Lemoine A, Pegorier JP, Parini A. Subcellular distribution of imidazoline-guanidinium-receptive sites in human and rabbit liver. Major localization to the mitochondrial outer membrane. J Biol Chem. 1991; 266:155-60.
  10. Tesson F, Prip-Buus C, Lemoine A, Pegorier JP & Parini A. Characterization of mitochondrial imidazoline-guanidinium receptive sites (IGRS) in liver. Am J Hypertens. 1995; 5, 805-825.
  11. Raddatz R, Parini A & Lanier SM. Localization of the imidazoline binding domain on monoamine oxidase. B Mol Pharmacol 1997; 52, 549-553.10.1124/mol.52.4.549
  12. Raddatz R, Savic SL, Bakthavachalam V, Lesnik J, Jasper JR, Mcgrath CR, Parini A, Lanier SM. Imidazoline-binding domains on monoamine oxidase B and subpopulations of enzyme. J Pharmacol Exp Ther 2000; 292, 1135-1145.10688633
  13. Head GA, & Mayorov DN. Imidazoline receptors, novel agents and therapeutic potential. Cardiovasc Hematol Agents Med Chem. 2006; 4:17-32.1652954710.2174/187152506775268758
  14. Raasch W, Muhle H, & Dominiak P. Modulation of MAO activity by imidazoline and guanidine derivatives. Ann N Y Acad Sci. 1999; 881:313-31.1041593210.1111/j.1749-6632.1999.tb09376.x
  15. Jones TZ, Giurato L, Guccione S. & Ramsay RR. Interactions of imidazoline ligands with the active site of purified monoamine oxidase A. FEBS J. 2007; 274, 1567-1575.1748020510.1111/j.1742-4658.2007.05704.x
  16. Holt A. & Baker GB. Metabolism of agmatine (clonidine-displacing substance) by diamine oxidase and the possible implications for studies of imidazoline receptors. Prog Brain Res. 1995; 106, 187-197.858465410.1016/S0079-6123(08)61215-7
  17. Su RB, Li J, Li X. & Qin BY. Down-regolation of MAO-B activity and imidazoline receptors in rat brain following chromic treatment of morphine. Acta Pharmacol. Sin. 2001; 22, 639-644.
  18. Ozaita A, Olmos G, Boronat MA, Lizcano JM, Unzeta M. & Garcia-Sevilla JA. Inhibition of monoamine oxidase A and B activities by imidazol(ine)/guanidine drugs, nature of the interaction and distinction from I2-imidazoline receptors in rat liver. Br J Pharmacol. 1997; 121, 901-912.10.1038/sj.bjp.0701214
  19. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976; 72:248-54.10.1016/0003-2697(76)90527-3942051
  20. Weissbach H, Smith TE, Daly JW, Witkop B, & Udenfriend S. A rapid spectrophotometric assay of mono-amine oxidase based on the rate of disappearance of kynuramine. J Biol Chem. 1960; 235:1160-3.13843767
  21. Holt A, Palcic MM. A peroxidase-coupled continuous absorbance plate-reader assay for flavin monoamine oxidases, copper-containing amine oxidases and related enzymes. Nat Protoc. 2006; 1(5):2498-505.10.1038/nprot.2006.402
  22. Holt A., Sharman D.F., Baker G.B., & Palcic M.M. (1997). A continuous spectrophotometric assay for monoamine oxidase and related enzymes in tissue homogenates. Anal Biochem. 244:384-92.902595610.1006/abio.1996.9911
  23. Tipton KF. Inhibition of monoamine oxidase by substituted hydrazines. Biochem J. 1992; 128:913-9.
  24. Kim H, Sablin SO, & Ramsay RR. Inhibition of monoamine oxidase A by beta-carboline derivatives. Arch Biochem Biophys. 1997; 337:137-42.10.1006/abbi.1996.97718990278
  25. Zomkowski AD, Hammes L, Lin J, Calixto JB, Santos AR, Rodrigues AL. Agmatine produces antidepressant-like effects in two models of depression in mice. Neuroreport. 2002; 13(4):387-91.1193014610.1097/00001756-200203250-00005
  26. Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr. 2013; 25(2):113-8. doi: 10.1111/j.1601-5215.2012.00675.x.10.1111/j.1601-5215.2012.00675.x25287313
  27. Laube G, Bernstein HG. Agmatine: multifunctional arginine metabolite and magic bullet in clinical neuroscience? Biochem J. 2017; 474(15):2619-2640.10.1042/BCJ2017000728747403
Language: English
Page range: 121 - 127
Published on: Apr 25, 2018
Published by: European Biotechnology Thematic Network Association
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2018 Loretta Mancinelli, Francesco Ragonese, Samuela Cataldi, Maria Rachele Ceccarini, Rossana G. Iannitti, Cataldo Arcuri, Bernard Fioretti, published by European Biotechnology Thematic Network Association
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.