Comparison of volatile and semi-volatile compounds in the five studied samples_
| CAS | Name | Flue-cured | Oriental (Turkish) | Burley | Dark air-cured | 1R6F filler | Organoleptic properties | Ref. numbers |
|---|---|---|---|---|---|---|---|---|
| 000064-19-7 | Acetic acid | + | + | — | + | + | flavor food additive | 26 |
| 000098-01-1 | Furfural | — | + | + | + | + | brown type flavor; aromatic odor reminiscent of almonds | 26 |
| 000098-00-0 | 2-Furanmethanol | — | + | — | — | + | burnt type flavor, bready type odor | 26 |
| 000620-02-0 | 2-Furancarboxaldehyde, 5-methyl- | + | + | + | + | + | fruity flavor, sweet, and caramel-like | 26 |
| 010230-62-3 | Furaneol | — | + | — | — | — | less sweet, caramel-like aroma | 31 |
| 000110-86-1 | Pyridine | — | + | — | — | + | fishy-type odor | 25 |
| 000765-87-7 | 1,2-Cyclohexanedione | — | + | — | — | — | nutty flavor and odor | 40 |
| 005989-27-5 | + | — | + | + | + | citrus flavor | 26 | |
| 000138-86-3 | Limonene | + | — | + | + | + | citrus flavor | 26 |
| 000765-70-8 | Cyclotene | — | + | + | — | — | rich caramel, burnt sugar, or maple syrup-like flavor | 25 |
| 000090-05-1 | Guiacol | — | + | — | — | — | woody flavor, phenolic odor | 40 |
| 010468-36-7 | Spiro[3.4]octan-5-one | — | + | — | — | — | woody, camphoraceous odor | 41 |
| 000118-71-8 | Maltol | + | — | — | — | — | a sweet aroma, of caramel and cotton candy-like | 42 |
| 000536-90-3 | Ethanone, 1-(3-methylphenyl)- | — | + | — | — | — | fruity, sweet, and floral aroma and fragrance | 26 |
| 028564-83-2 | 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl- | + | + | — | — | + | sweet, caramel-like notes | 26 |
| 019895-35-3 | 6-Ethyl-5,6-dihydro-2H-pyran-2-one | + | — | — | — | — | sweet, caramel-like, coconut, slightly creamy | 43 |
| 001073-96-7 | 5-Hydroxymaltol | + | — | — | — | — | sweet, caramel-like, slightly toasty aroma | 26 |
| 000067-47-0 | 5-Hydroxymethylfurfural | + | — | — | — | — | mildly sweet, caramel-like | 26 |
| 007786-61-0 | 2-Methoxy-4-vinylphenol | — | + | — | — | — | smoky, clove-like, spicy, and slightly sweet | 26 |
| 054868-48-3 | Solanone | — | — | + | — | — | warm, woody, and tobacco-like scent | 26 |
| 000108-95-2 | Phenol | + | — | + | + | — | smoky and tar-like aroma | 44 |
| 038818-55-2 | Megastigmatrienone | + | + | + | + | + | tobacco / insence aroma | 25 |
| 000581-50-0 | 2,3'-Dipyridyl | + | + | + | + | + | tobacco taste and flavor improving agent | 25 |
| 000504-96-1 | Neophytadiene | + | + | + | + | + | tobacco flavor enhancer; green, herbal, and mildly sweet aroma | 35 |
| 004674-50-4 | Nootkatone | — | — | — | — | + | scent and flavor of grapefruit | 26 |
| 025491-20-7 | Patchoulane | — | — | + | + | — | mild, earthy, and camphoraceous aroma | 26 |
| 000475-20-7 | Longifolene | — | + | + | + | + | woody, pine-like, resinous scent | 26 |
| 024034-73-9 | trans-Geranylgeraniol | + | + | + | + | + | floral, rose-like scent. | 26 |
| 034318-21-3 | Ionol, 3-oxo- | + | + | — | + | — | warm, woody, and floral aroma and flavor | 26 |
| 000150-86-7 | Phytol | — | + | — | + | — | grassy and green notes | 45 |
| 025269-17-4 | Thunbergol | + | + | + | + | + | characteristic, pleasant aroma | 43 |
| 004602-84-0 | Farnesol | — | — | + | + | + | sweet, floral, with a delicate lily-of-the-valley nuance | 26 |
Classification of volatile compounds identified in research tobaccos and tobacco from 1R6F reference cigarettes_
| Chemical Class | Flue-cured | Oriental (Turkish) | Burley | Dark air-cured | 1R6F filler |
|---|---|---|---|---|---|
| Carboxylic acids | 1 | 1 | — | 1 | 1 |
| Furan derivatives | 2 | 4 | 2 | 2 | 3 |
| Pyranones / lactones | 4 | 1 | — | — | 1 |
| Hydroxy ketones | — | — | — | — | — |
| Ketones / diketones | — | 4 | 2 | — | 2 |
| Phenolics | 1 | 2 | 1 | 1 | 1 |
| Monoterpenes | 2 | — | 2 | 2 | 1 |
| Norisoprenoids | 2 | 2 | 1 | 2 | 1 |
| Sesquiterpenes | — | 1 | 2 | 1 | 1 |
| Sesquiterpenoid alcohols | 1 | 1 | 1 | 1 | 1 |
| Sesquiterpenoid diols | — | — | 1 | 1 | — |
| Diterpenes / diterpenoids | 2 | 3 | 2 | 3 | 2 |
| Bipyridine derivatives | 1 | 1 | 1 | 1 | 1 |
| Nitrogen heterocycles | — | 1 | — | — | 1 |
Estimated natural flavor of research tobaccos and tobacco from 1R6F reference cigarettes_
| Sample | Aroma | Taste |
|---|---|---|
| Flue-cured | Rich, sweet, and fruity; caramel-like from high pyranones; citrus/pine from monoterpenes and norisoprenoids | Mild acidity; light phenolic character; slightly woody or nutty undertones |
| Oriental (Turkish) | Complex and layered; smoky-caramel and roasted from furans and ketones; spicy-dry from sesquiterpenes and diterpenes | Astringent and slightly bitter; phenolic and dry aftertaste; lingering spice |
| Burley | Subtle aroma; low in sweet lactones; earthy and woody from sesquiterpenes; minor smoky hints from furans | Noticeably bitter and dry; less acidic; mild nutty/burnt note from diketones |
| Dark air-cured | Bold and heavy; roasted and resinous from furans and diterpenoids; earthy-spicy from terpenes | Full-bodied and bitter; phenolic and leathery taste with slight smoky-charred notes |
| 1R6F Filler | Mixed aroma; moderately sweet and woody; pyranones add caramel note; dry herbal from diterpenes | Balanced but slightly bitter; dry and faintly astringent, likely due to phenolics and furans |