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Indoor Air Quality Assessment During the Use of Tobacco and Nicotine Products* Cover

Indoor Air Quality Assessment During the Use of Tobacco and Nicotine Products*

Open Access
|Dec 2025

Figures & Tables

Figure 1.

Photographic image of the indoor air testing facility.
Photographic image of the indoor air testing facility.

Levels of selected analytes in indoor air for the ten occupant scenarios_ Analytes shown are those assessed which were above the lower limit of quantification in at least one testing scenario_ For full raw and baseline-adjusted data for all analytes, refer to Supplementary Tables 3 and 5, respectively_ Analytes in bold are those mandated for lowering in cigarette smoke in the World Health Organization Study Group on Tobacco Product Regulation (TobReg) proposal (22)_ Data for the unoccupied baseline and ten-occupant baseline measurements are raw data_ For the scenarios in which ten occupants were in the testing room using the OOKA electronic waterpipe, using EVPs, or smoking cigarettes, data were normalised to the baseline analyte levels when ten occupants were in the testing room but refraining from the use of tobacco and nicotine products_ Data for the ten unattended waterpipes scenario, in which no participants were in the testing room, were normalised to the analyte levels during the unoccupied baseline measurement_

Analyte/parameter (units)LLOQBaseline-adjusted
Unoccupied baselineBaseline ten occupantsTen occupants OOKATen occupants EVPsTen unattended waterpipesTen occupants cigarettes
PM10 (μg/m3)NA9.131.6826.2920.578.8499.2
PM2.5 (μg/m3)NA5.68.3803.5886.878.8497.6
CO (ppm)0.32.22.21.20.2160.025.8
CO2 (ppm)1717.72116.61480.7225.73128.5719.2
Formaldehyde (μg/m3)0.16.720.07.0-7.01293.3140.0
Glycerol (μg/m3)0.1<0.1<0.15.17.010.91.2
Metals
Copper (μg/m3)0.4<0.41.1-0.6-0.17.60.1
Manganese (μg/m3)0.4<0.40.8-0.4-0.30.05.2
VOCs
Dichloromethane (μg/m3)1.7<1.7<1.70.00.00.11.1
Carbon disulphide (μg/m3)1.72.45.5-2.5114.53.89.5
Benzene (μg/m3)0.83<0.83<0.830.470.0046.2129.2
Toluene (μg/m3)0.832.23.81.20.217.8176.2
Ethylbenzene (μg/m3)0.170.671.00.500.001.127.0
Styrene (μg/m3)0.832.97.8-5.6-4.1-0.125.2
Naphthalene (μg/m3)0.516.313.05.05.011.72.0
n-Hexane (μg/m3)0.830.751.3-0.300.200.088.7
Isopropanol (μg/m3)1.72.53.00.70.54.07.0
Phenol (μg/m3)1.7<1.7<1.70.10.03.126.3
Propylene glycol monomethyl ether (μg/m3)1.7<1.7<1.75.53.00.00.0
Xylene (μg/m3)0.512.94.71.5-0.729.188.3
PAHs
Acenaphthylene (μg/m3)0.083<0.083<0.0830.000.000.000.25
Acenaphthene (μg/m3)0.083<0.083<0.0830.000.000.000.10
Fluorene (μg/m3)0.083<0.083<0.0830.000.000.000.15
Phenanthrene (μg/m3)0.083<0.083<0.0830.000.000.090.15
TSNAs
NNN (μg/m3)0.009<0.009<0.0090.000.000.000.058
NAT (μg/m3)0.009<0.009<0.0090.000.000.000.033
NAB (μg/m3)0.009<0.009<0.0090.000.000.000.005
NNK (μg/m3)0.009<0.009<0.0090.000.000.000.599

Levels of selected analytes in indoor air for the one occupant scenarios_ Analytes shown are those assessed which were above the lower limit of quantification in at least one testing scenario_ For full raw and baseline-adjusted data for all analytes, refer to Supplementary Tables 2 and 4, respectively_ Analytes in bold are those mandated for lowering in cigarette smoke in the World Health Organization Study Group on Tobacco Product Regulation (TobReg) proposal (22)_ Data for the unoccupied baseline and one occupant baseline measurements are raw data_ For the scenarios in which one occupant was in the testing room using the OOKA electronic waterpipe, using an EVP, or smoking cigarettes, data were normalised to the baseline analyte levels when one occupant was in the testing room but refraining from the use of tobacco and nicotine products_

Analyte (units)LLOQBaseline-adjusted
Unoccupied baselineBaseline one occupantOne occupant OOKAOne occupant EVPOne occupant waterpipe
PM10 (μg/m3)NA9.112.1313.424.1500.4
PM2.5 (μg/m3)NA5.65.5311.226.1486.8
CO (ppm)0.32.22.00.10.817.4
CO2 (ppm)1717.7868.4220.4507.3700.7
Formaldehyde (μg/m3)0.16.76.76.30.026.3
Glycerol (μg/m3)0.1<0.1<0.10.250.003.40
Metals
Chromium (μg/m3)0.4<0.40.60.10.10.2
Copper (μg/m3)0.4<0.40.90.2-0.10.4
Manganese (μg/m3)0.4<0.40.60.2-0.20.1
VOCs
Dichloromethane (μg/m3)1.7<1.73.02.30.35.3
Carbon disulphide (μg/m3)1.72.425.0-20.0-21.7-11.0
Chloroform (μg/m3)0.83<0.83<0.837.50.00.0
Benzene (μg/m3)0.83<0.83<0.830.00.370.30
Toluene (μg/m3)0.832.23.71.34.66.3
Ethylbenzene (μg/m3)0.170.670.830.671.72.0
Styrene (μg/m3)0.832.92.50.3-0.21.3
Naphthalene (μg/m3)0.516.35.34.710.710.7
n-Hexane (μg/m3)0.830.751.00.000.301.2
Isopropanol (μg/m3)1.72.51.80.26.59.2
Propylene glycol monomethyl ether (μg/m3)1.7<1.79.533.5-6.723.5
Xylene (μg/m3)0.512.93.03.17.88.8
Language: English
Page range: 230 - 241
Submitted on: Jun 17, 2025
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Accepted on: Nov 28, 2025
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Published on: Dec 29, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Peter J. Wilkinson, Anna Clarke, Ian M. Fearon, Ronan Barry, published by Institut für Tabakforschung GmbH
This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License.