Table 1.
Main physical characteristics of a flavored Toscanello© cigar. Diameter-1 and -2 are measured at cigar's head (mouth end) and foot (fire end), respectively. Values are expressed as mean ± standard deviation.
| Cigar | Weight (g) | Length (mm) | Draw resistance (mmWG) | Diameter-1 (mm) | Diameter-2 (mm) |
|---|---|---|---|---|---|
| Flavored Toscanello© | 3.996 ± 0.368 | 77.62 ± 1.14 | 94.38 ± 23.49 | 10.07 ± 0.61 | 13.89 ± 0.49 |
Table 2.
Main physical characteristics of three flavored Toscanello cigars routinely produced in Manifatture Sigaro Toscano with low (M1), medium (M2), and high (M3) propylene glycol (PG) content in the flavoring blend. Diameter-1 and -2 are measured at cigar's head (mouth end) and foot (fire end), respectively. Values are expressed as mean ± standard deviation.
| Cigar | Weight (g) | Length (mm) | Draw resistance (mmWG) | Diameter-1 (mm) | Diameter-2 (mm) |
|---|---|---|---|---|---|
| M1 | 3.806 ± 0.343 | 77.34 ± 1.25 | 91.26 ± 22.47 | 10.19 ± 0.61 | 13.76 ± 0.41 |
| M2 | 3.932 ± 0.330 | 77.55 ± 1.12 | 89.50 ± 23.61 | 9.84 ± 0.52 | 13.72 ± 0.44 |
| M3 | 4.142 ± 0.346 | 77.81 ± 1.04 | 99.41 ± 23.02 | 10.18 ± 0.65 | 14.19 ± 0.47 |

Figure 1.
Picture of a typical flavored Toscanello©.
Table 3.
Mainstream smoke yields of CO, nicotine, water, NFDPM, TPM and puff number for M1, M2 and M3 cigars. Given are the mean values and 95% confidence intervals (CI) in mg/cigar.
| Cigara | CO (mg/cig) | Nicotine (mg/cig) | Water (mg/cig) | NFDPM (mg/cig) | TPM (mg/cig) | Puff number | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | |
| M1 | 88.45 | 86.19;90.71 | 3.588 | 3.472;3.704 | 4.432 | 4.174;4.689 | 41.18 | 40.06;42.31 | 49.13 | 47.76;50.50 | 58.27 | 56.57;59.97 |
| M2 | 101.19 | 98.50;103.88 | 2.729 | 2.648;2.809 | 6.075 | 5.798;6.353 | 37.39 | 36.43;38.36 | 46.20 | 45.02;47.37 | 65.44 | 63.91;66.98 |
| M3 | 112.20 | 109.79;114.61 | 2.395 | 2.337;2.453 | 8.430 | 8.082;8.778 | 44.34 | 43.42;45.27 | 55.17 | 53.97;56.37 | 65.53 | 64.38;66.68 |

Figure 2.
Plots of means and 95% CI, expressed in milligram per cigar, of CO, nicotine, water and NFDPM in mainstream smoke of M1, M2 and M3 cigars.
Table 4.
Mainstream smoke yields of CO, nicotine, water and NFDPM for M1, M2 and M3 cigars. Given are the mean values and 95% confidence intervals (CI) in mg/g tobacco.
| Cigara | CO (mg/g) | Nicotine (mg/g) | Water (mg/g) | NFDPM (mg/g) | ||||
|---|---|---|---|---|---|---|---|---|
| Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | |
| M1 | 26.95 | 26.23;27.68 | 1.104 | 1.060;1.148 | 1.362 | 1.278;1.445 | 12.67 | 12.22;13.11 |
| M2 | 30.28 | 29.48;31.08 | 0.827 | 0.797;0.857 | 1.833 | 1.744;1.921 | 11.31 | 10.94;11.67 |
| M3 | 33.19 | 32.44;33.95 | 0.716 | 0.695;0.737 | 2.517 | 2.404;2.630 | 13.23 | 12.89;13.58 |
Table 5.
Main physical characteristics of experimental cigars (A, B, C). Diameter-1 and -2 are measured at cigar's head (mouth end) and foot (fire end), respectively. Values are expressed as mean ± standard deviation.
| Cigara | Weight (g) | Length (mm) | Draw resistance (mmWG) | Diameter-1 (mm) | Diameter-2 (mm) |
|---|---|---|---|---|---|
| A | 4.089 ± 0.231 | 77.07 ± 0.98 | 111.93 ± 18.93 | 9.44 ± 0.61 | 13.68 ± 0.43 |
| B | 4.042 ± 0.306 | 77.03 ± 0.72 | 92.13 ± 13.42 | 9.39 ± 0.67 | 13.98 ± 0.60 |
| C | 4.171 ± 0.155 | 77.13 ± 0.73 | 99.90 ± 20.39 | 9.95 ± 0.61 | 14.44 ± 0.77 |
Table 6.
Propylene glycol (PG) and water percent content in whole cigar (filler + wrapper) of the three experimental cigars produced by adding an aqueous solution containing 0 (A), low (B) and high (C) PG amount. Target PG% are also reported.
| Cigar | %PG (Target) | %PG (Actual) | % Water |
|---|---|---|---|
| A | 0 | 0 | 8.35 |
| B | 3.11 | 3.06 | 8.29 |
| C | 8.50 | 8.56 | 8.96 |
Table 7.
Mainstream smoke yields of CO, nicotine, water, NFDPM, TPM and puff number for the experimental Cigars A, B and C. Given are the mean values and 95% confidence intervals (CI) in mg/cigar.
| Cigara | CO (mg/cig) | Nicotine (mg/cig) | Water (mg/cig) | NFDPM (mg/cig) | TPM (mg/cig) | Puff number | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | |
| A | 49.74 | 45.13;54.35 | 3.806 | 3.536;4.077 | 2.807 | 2.440;3.174 | 31.43 | 29.33;33.53 | 38.04 | 35.44;40.64 | 76.16 | 73.11;79.21 |
| B | 62.20 | 58.00;66.41 | 3.970 | 3.728;4.212 | 4.491 | 4.004;4.978 | 35.78 | 33.86;37.70 | 44.24 | 41.84;46.63 | 69.01 | 65.73;72.29 |
| C | 87.84 | 82.75;92.94 | 3.409 | 3.212;3.606 | 6.541 | 5.947;7.135 | 43.26 | 41.16;45.35 | 53.21 | 50.54;55.88 | 68.94 | 66.58;71.31 |

Figure 3.
Plots of means and 95% CI, expressed in mg/cigar, of CO, nicotine, water and NFDPM in mainstream smoke of A, B, and C Cigars.
Table 8.
Mainstream smoke yields of CO, nicotine, water and NFDPM for the experimental cigars A, B, C. Given are the mean values and 95% confidence intervals (CI) in mg/g tobacco.
| Cigara | CO (mg/g) | Nicotine (mg/g) | Water (mg/g) | NFDPM (mg/g) | ||||
|---|---|---|---|---|---|---|---|---|
| mean | 95% CI | mean | 95% CI | mean | 95% CI | mean | 95% CI | |
| A | 13.40 | 12.02;14.79 | 1.026 | 0.936;1.116 | 0.756 | 0.652;0.860 | 8.46 | 7.78;9.15 |
| B | 17.42 | 16.25;18.59 | 1.119 | 1.034;1.204 | 1.264 | 1.115;1.414 | 10.07 | 9.39;10.74 |
| C | 25.55 | 24.07;27.03 | 0.994 | 0.931;1.058 | 1.909 | 1.724;2.093 | 12.60 | 11.93;13.28 |