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Laboratory Evaluation of the CReSSmicro™ Portable Topography Device: Implications for Clinical Research Cover

Laboratory Evaluation of the CReSSmicro™ Portable Topography Device: Implications for Clinical Research

Open Access
|May 2014

Abstract

Performance of the CReSSmicro™ v.2.0.0 portable smoking topography device was evaluated in a controlled laboratory environment using a calibrated smoking machine to generate known, reproducible smoking topographies. Device performance was evaluated using unlit and lit cigarettes over a range of puff volumes (25 to 100 mL) at 2 s puff duration using a sine wave profile. The device missed 93% and 100% of the 25 mL/2 s puffs for unlit and lit cigarettes, respectively. The device underreported puff durations for the entire volume range, i.e., from 40 mL (0.9 ± 0.17 s) to 100 mL (1.6 ± 0.11 s) for both unlit and lit cigarettes. Puff volumes were under reported for lower volumes from 40 mL (25.6 ± 5.5 mL) to 70 mL (68.8 ± 3.7 mL) for both unlit and lit cigarettes and slightly over reported for higher volumes from 85 mL (89.4 ± 7.6 mL) to 100 mL (103.4 ± 9.8 mL) for lit cigarettes. Experimental results indicated that a 12.5-20mL/s (750-1,200 mL/min) flow threshold for puff recognition was responsible for the observed results. This study reinforces the importance of fully understanding device performance prior to performing clinical studies of human smoking topography. [Beitr. Tabakforsch. Int. 26 (2014) 19-25]

Language: English
Page range: 19 - 25
Submitted on: Dec 17, 2013
Accepted on: Mar 20, 2014
Published on: May 1, 2014
Published by: Institut für Tabakforschung GmbH
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2014 Michael J. Oldham, Susan E. Plunkett, Michael T. Fisher, Kenneth H. Shafer, Michael J. Morton, published by Institut für Tabakforschung GmbH
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.