References
- 1. Kennaway, E.L. and I. Hieger: Carcinogenic sub-stances and their fluorescence spectra; British Med. J. I (1930) 1044–1046.
- 2. Cook, J.W., C.L. Hewett, and I. Hieger: The isolation of a cancer-producing hydrocarbon from coal tar; J. Chem. Soc. I, II and III (1933) 395–405.
- 3. Blacklock, J.W.S.: The production of lung tumours in rats by 3:4 benzpyrene, methylcholanthrene and the condensate from cigarette smoke; British J. Canc. 11 (1957) 181–191.
- 4. Wynder, E. and D. Hoffmann: Tobacco and Tobacco Smoke: Studies in Experimental Carcinogenesis; Aca-demic Press New York and London, 1967.
- 5. Goldman, R., L. Enewold, E. Pellizzari, J.B. Beach, E.D. Bowman, S.S. Krishnan, and P.G. Shields: Smoking Increases Carcinogenic Polycyclic Aromatic Hy-drocarbons in Human Lung Tissue; Canc. Res. 61 (2001) 6367–6371.
- 6. Rubin, H.: Historical Review, Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates; Carcinogen. 22 (2001) 1903–1930.
- 7. Thielen, A., H. Klus, and L. Müller: Tobacco smoke: Unraveling a controversial subject; Exp. Tox. Path. 60 (2008) 141–156.
- 8. United States Public Laws: Stat. 1776: The Family Smoking Prevention and Tobacco Control Act; 2009, available at: http://www.fda.gov/tobaccoproducts (ac-cessed May 01, 2013).
- 9. Center for Tobacco Products, United States Food and Drug Administration: Guidance for Industry, Reporting Harmful and Potentially Harmful Constituents in Tobacco Products and Tobacco Smoke Under Section 904(a) (3) of the Federal Food, Drug, and Cosmetic Act; 2012; available at: http://www.fda.gov/tobacco guidance (accessed May 01 2013).
- 10. Irigaray, P., S. Lacomme, L. Mejean, and D. Bel-pomme: Ex vivo study of incorporation into adipocytes and lipolysis-inhibition effect of polycyclic aromatic hydrocarbons; Tox. Lett. 187 (2009) 35-39.
- 11. International Organisation for Standardisation (ISO): International Standard ISO 22634: Determination of benzo[a]pyrene in cigarette mainstream smoke -method using gas chromatography/mass spectrometry; ISO, Geneva, Switzerland, 2007.
- 12. de Hoffmann, E.: Tandem mass spectrometry: A primer; J. Mass Spectrom 31 (1996) 129-137.10.1002/(SICI)1096-9888(199602)31:2<129::AID-JMS305>3.0.CO;2-T
- 13. CORESTA Recommended Method No. 58: Determination of benzo[a]pyrene in cigarette mainstream smoke -method using gas chromatography/mass spectrometry; 2004 revised 2013, Cooperation Centre for Scientific Research Relative to Tobacco, Paris, France.
- 14. Personal communication by e-mail (Sept. 29, 2008) from K. Greenwood: Philip Morris International Research and Development: Proficiency Test for Mainstream Smoke Constituents Analysis 2007/2008.
- 15. Intorp, M., S. Purkis, M. Whittaker, and W. Wright: Determination of “Hoffman Analytes” in Cigarette Mainstream Smoke. The CORESTA 2006 Joint Experi-ment; Beitr. Tabakforsch. Int. 23 (2009) 161-202.
- 16. Personal communication by e-mail (Feb. 07, 2013) from G. Jaccard: Philip Morris International Research and Development: Collaborative Test Mainstream Smoke Constituents; Analysis of data collected in Oc-tober - December 2012; ISO Smoking Regime.
- 17. International Organisation for Standadarsation (ISO): International Standard ISO 3308: Routine analytical cigarette-smoking machine - Definitions and standard conditions; ISO, Geneva, Switzerland, 2000.
- 18. Health Canada Method T-115; available at http://www.hc-sc.gc.ca (accessed May 01, 2013).
- 19. Robb, E.W., G.C. Guvernator, M.D. Edmonds, and A. Bavley: Analysis of Polycyclic Hydrocarbons; Beitr. Tabakforsch. 3 (1965) 278-284.
- 20. Gmeiner, G., G. Stehlik, and H. Tausch: Determination of seventeen polycyclic aromatic hydrocarbons in tobacco smoke condensate; J. Chromatogr. 767 (1997) 163-169.
- 21. LGC Report GC15/M09/02: Report commissioned by the UK Department of Health: Comparison of mainstream smoke yields of tar, nicotine, carbon monoxide and polycyclic hydrocarbons from cigarettes and small cigars; 2002, available at: http://legacy.library.ucsf edu/documentStore/g/q/p/gqp34a00/Sgqp34a00.pdf (accessed June 17, 2013).
- 22. Rodgman, A. and CR. Green: Toxic Chemicals in Cigarette Mainstream Smoke - Hazard and Hoopla; Beitr. Tabakforsch. Int. 20 (2003) 481-545.
- 23. Roemer, E., H. Schramke, H. Weiler, A. Buettner, S. Kausche, S. Weber, A. Berges, M. Stueber, M. Muench, E. Trelles-Sticken, J. Pype, K. Kohlgrueber, H. Voekel, and S. Wittke: Mainstream Smoke Chemis-try and In Vitro and In Vivo Toxicity of the Reference Cigarettes 3R4F and 2R4F; Beitr. Tabakforsch. Int. 25 (2012) 316-335.
- 24. International Organisation for Standadarsation (ISO): International Standard ISO 3402: Tobacco and tobacco products - Atmosphere for conditioning and testing; ISO, Geneva, Switzerland, 1999.
- 25. International Organisation for Standadarsation (ISO): International Standard ISO 4387: Determination of Total and Nicotine-Free Dry Particulate Matter using a Routine Analytical Cigarette Smoking Machine Deter-mination of Total Particulate Matter and Preparation for Water and Nicotine Measurements; ISO, Geneva, Switzerland, 2000.
- 26. Health Canada Method T-103; available at http://www.hc-sc.gc.ca (accessed May 15, 2013).
- 27. LGC Report FN40/M26/00: Report commissioned by the UK Department of Health: Comparison of Yields of Benzo[a]pyrene from USA and UK Blend Cigarettes, 2000, available at http://legacy.library.ucsf. edu/tid/mqh17a00/pdf (accessed June 17, 2013).
- 28. Kalaitzoglou, M. and C. Samara: Distribution of Poly-cyclic Aromatic Hydrocarbons between the Particulate and the Gas Phase of Mainstream Cigarette Smoke in Relation to Cigarette Technological Characteristics; Beitr. Tabakforsch. Int. 21 (2005) 331–344.