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The Complexity of Tobacco and Tobacco Smoke Cover

The Complexity of Tobacco and Tobacco Smoke

Contributions to Tobacco & Nicotine Research
Volume 24 (2011): Issue 5 (May 2011)
By: TA Perfetti and  A Rodgman  
Open Access
|Dec 2014

References

  1. 1. Aasen, A. J., J. R. Hlubucek, and C. R. Enzell: New tobacco constituents originating from terpenoid precursors; 9th Internat. Symp. Chem. Natural Products, Ottawa, Ontario, Canada (1974).
    Search in Google Scholar
  2. 2. Aasen. A. J., T. Nishida, C. R. Enzell, and M. Devreux: Tobacco chemistry. 37. The absolute configuration of prenylsolanone, (9S)-6,12-dimethyl-9-isopropyl-trideca-5E,10E,12-trien-2-one. A northunberganoid of Nicotiana tabacum L.; Acta Chem. Scand. B30 (1976) 178–179.
    Search in Google Scholar
  3. 3. Almqvist, S. O., A. J. Aasen, J. R. Hlubucek, B. Kim-land, and C. R. Enzell: Tobacco chemistry. 23. Structures and syntheses of four new norisoprenoid furans from Greek Nicotiana tabacum L.; Acta Chem. Scand. B28 (1974) 528–532.
    Search in Google Scholar
  4. 4. Aviado, D. M.: Complex mixtures of tobacco smoke and the occupational environment; Chapter 4 in: Patty's Industrial Hygiene and Toxicology, 4th Edition, Vol. 2, Pt. A, edited by G. D. Clayton and F. E. Clay-ton, John Wiley and Sons, Inc., New York, NY (1993) 107–148.
    Search in Google Scholar
  5. 5. Binkley, J.: Analysis of pesticides in smokeless tobacco by comprehensive two-dimensional gas chromatography-time of flight mass spectrometry (GC×GC-TOFMS); LC-GC Chromatography Online, September 1, 2009.
    Search in Google Scholar
  6. 6. Borgerding, M. and H. Klus: Analysis of complex mixtures – Cigarette smoke; Exp. Tox. Pathol. 57 (Suppl. 1), (2005) 43–73.
    Search in Google Scholar
  7. 7. Browne, C. L., C. H. Keith, and R. E. Allen: The effect of filter ventilation on the yield and composition of mainstream and sidestream smoke; 32nd Tobacco Chemists’ Research Conference, Program Booklet and Abstracts, Vol. 32, Paper No. 16, 1978, p. 8; CORESTA 1978 Symp., Sofia, Bulgaria, CORESTA Inf. Bull., Spec. Edition 1978: Paper ST-01, 124; Beitr. Tabakforsch. Int. 10 (1980) 81–90.
    Search in Google Scholar
  8. 8. Chuman, T.: Chemical studies on aroma constituents of Turkish tobacco; Sci. Papers, Cent. Res. Inst., Japan Monopoly Corp. 119 (1977) 45–92.
    Search in Google Scholar
  9. 9. Chuman, T., H. Kaneko, T. Fukuzumi, and M. No-guchi: Isolation of two terpenoid acids 4-isopropyl-7-methyl-5E,7-octadienoic acid and 3-isopropyl-6-methyl-4E,6-heptadienoic acid from Turkish tobacco; Agr. Biol. Chem. 38 (1974) 2295–2296.
    Search in Google Scholar
  10. 10. Chuman, T., H. Kaneko, T. Fukuzumi, and M. No-guchi: Acidic aroma constituents of Turkish tobacco: Terpenoid acids related to tobacco thunberganoids; Agr. Biol. Chem. 40 (1976) 587–591.
    Search in Google Scholar
  11. 11. Chuman, T., H. Kaneko, and M. Noguchi: The structure of a new terpenoid acid, 1-a-methyl-3-a-isopropyl-cyclopentane-1-?,2-?-dicarboxylic acid, isolated from Turkish tobacco; Agr. Biol. Chem. 42 (1978) 203–204.
    Search in Google Scholar
  12. 12. Chuman, T. and M. Noguchi: Isolation of a new terpenoid acid 2-methyl-5-isopropyl-1-cyclopentene-1-carboxylic acid from Turkish tobacco; Agr. Biol. Chem. 39 (1975) 567–568.
    Search in Google Scholar
  13. 13. Chuman, T. and M. Noguchi: Isolation of new terpe-noid acids (!)-3-methyl-6-isopropyl-9-oxo-2E,4E-decadienoic acid and 3-isopropyl-6-oxo-2Z-heptenoic acid from Turkish tobacco; Agr. Biol. Chem. 39 (1975) 1169–1171.
    Search in Google Scholar
  14. 14. Chuman, T. and M. Noguchi: The structure of a new terpenoic acid, 6(S)-isopropyl-3?-methyl-3?-hydroxy-9-oxo-4E-decenoic acid, isolated from Turkish tobacco; Agr. Biol. Chem. 40 (1976) 1793–1796.
    Search in Google Scholar
  15. 15. Chuman, T. and M. Noguchi: Acidic aroma consti-tuents of Turkish tobacco; Agr. Biol. Chem. 41 (1977) 1021–1030.
    Search in Google Scholar
  16. 16. Chuman, T., M. Noguchi, A. Ohkubo, and S. Toda: The structure of a novel terpenoid acid, “-hydroxy-4,9-dimethyl-6E,9E-dodecadienedioic”, isolated from Turkish tobacco; Tetrahedron Lett. 18 (1977) 3045–3058.
    Search in Google Scholar
  17. 17. Demole, E. and D. Berthet: A chemical study of burley tobacco flavour (Nicotiana tabacum L.). I. Volatile to medium-volatile constituents (b. p. # 84°/0. 001 Torr); Helv. Chim. Acta 55 (1972) 1866–1882.
    Search in Google Scholar
  18. 18. Demole, E. and D. Berthet: A chemical study of burley tobacco flavour (Nicotiana tabacum L.). II. Medium-volatile, free acidic constituents (b. p. ~84–114°/0. 001 Torr); Helv. Chim. Acta 55 (1972) 1898–1901.
    Search in Google Scholar
  19. 19. Demole, E. and C. Demole: A chemical study of burley tobacco flavour (Nicotiana tabacum L.). V. Identification and synthesis of the novel terpenoid alkaloids 1,3,6,6-tetramethyl-5,6,7,8-tetrahydroiso-quinolin-8-one and 3,6,6-trimethyl-5,6-dihydro-7H-2-pyrindin-2-one; Helv. Chim. Acta 58 (1975) 523–531.
    Search in Google Scholar
  20. 20. Demole, E. and C. Demole: A chemical study of burley tobacco flavour (Nicotiana tabacum L.). VII. Identification and synthesis of twelve irregular terpe-noid alkaloids related to solanone including 7,8-dioxabicyclo[3. 2. 1]octane and 4,9-dioxabicyclo-[3. 3. 1]nonane derivatives; Helv. 187Chim. Acta 58 (1975) 1867–1880.
    Search in Google Scholar
  21. 21. Demole, E., C. Demole, and D. Berthet: A chemical study of burley tobacco flavour (Nicotiana tabacum L.). III. Structure determination and synthesis of 5-(4-methyl-2-furyl)-6-methylheptan-2-one (“solanofuran”) and of 3. 4. 7-trimethyl-1,6-dioxaspiro[4,5]dec-3-en-2-one (“spiroxabovolide”). Two new flavor components of burley tobacco; Helv. Chim. Acta 56 (1973) 265–271.
    Search in Google Scholar
  22. 22. Demole, E. and P. Dietrich: A chemical study of burley tobacco flavour (Nicotiana tabacum L.); in: Recent advances in the chemical composition of tobacco and tobacco smoke, edited by J. L. McKenzie, R. M. Ikeda, T. R. Terrill, D. G. Vickroy, and D. B. Walters, Proc. Am. Chem. Soc. Symp., New Orleans, LA (1977) 1–36.
    Search in Google Scholar
  23. 23. Dickerson, J. P., D. L. Roberts, C. W. Miller, R. A. Lloyd, and C. E. Rix: Flue-cured tobacco flavor. II. Constituents arising from amino acid-sugar reactions; Tob. Sci. 20 (1976) 59–63.
    Search in Google Scholar
  24. 24. Dipple, A., R. C. Moschel, and C. A. H. Bigger: Polynuclear aromatic carcinogens; Chapter 2 in: Chemical carcinogens. 2nd edition, edited by C. E. Searle, American Chemical Society Monograph 182, American Chemical Society, Washington, DC (1984) 41–163.
    Search in Google Scholar
  25. 25. Environmental Protection Agency (EPA): Health effects of passive smoking: Assessment of lung cancer in adults and respiratory disorders in children; Draft Document EPA/600/6-90/006A (May 1990).
    Search in Google Scholar
  26. 26. Environmental Protection Agency (EPA): Report of the EPA review workshop on alpha2u-globulin: Association with renal toxicity and neoplasia in the male rat; US EPA, Washington, DC (1991).
    Search in Google Scholar
  27. 27. Federal Trade Commission: Cigarettes: Testing for tar and nicotine content; Fed. Register 32 (1967) 11178; Pillsbury, H. C., C. C. Bright, K. J. O'Connor, and F. W. Irish: Tar and nicotine in cigarette smoke; J. Assoc. Off. Anal. Chem. 52 (1969) 458–462.
    Search in Google Scholar
  28. 28. Fujimori, T., R. Kasuga, H. Kaneko, and M. Noguchi: A new acetylenic diol, 3-hydroxy-7,8-dehydro-a-ionol, from burley Nicotiana tabacum; Phytochemistry 14 (1975) 2095.
    Search in Google Scholar
  29. 29. Fujimori, T., R. Kasuga, H. Kaneko, and M. Noguchi: Isolation of R(!)-3-hydroxy-a-ionone from burley tobacco; Agr. Biol. Chem. 38 (1974) 891–892.
    Search in Google Scholar
  30. 30. Fujimori, T., R. Kasuga, H. Kaneko, and M. Noguchi: Isolation of 3-(4,8,12-trimethyltridecyl)-furan (“phyto-furan”) from burley tobacco; Agr. Biol. Chem. 38 (1974) 2293–2294.
    Search in Google Scholar
  31. 31. Fujimori, T., R. Kasuga, H. Kaneko, and M. Noguchi: Isolation of 3-hydroxy-a-ionol from burley tobacco; Agr. Biol. Chem. 39 (1975) 913–914.
    Search in Google Scholar
  32. 32. Fujimori, T., R. Kasuga, H. Matsushita, H. Kaneko, and M. Noguchi: Neutral aroma constituents in burley tobacco; Agr. Biol. Chem. 40 (1976) 303–315.
    Search in Google Scholar
  33. 33. Fukuzumi, T., H. Kaneko, and H. Takahara: Studies on the chemical constituents of tobacco leaves. Part III. Isolation of a (!)-2-isopropyl-5-oxohexanoic acid from Turkish tobacco leaves and absolute configuration of solanone; Agr. Biol. Chem. 31 (1967) 607–610.
    Search in Google Scholar
  34. 34. Fukuzumi, T., H. Takahara, H. Kaneko, and I. Onishi: Studies of the chemical constituents of tobacco leaves. I. Organic acids in Turkish tobacco; J. Agr. Chem. Soc. Japan 39 (1965) 199–203.
    Search in Google Scholar
  35. 35. Gold, L. S., T. H. Slone, and B. N. Ames: What do animal cancer tests tell us about human cancer risk?: Overview of analyses of the carcinogenic potency database; Drug Metab. Rev. 30 (1998) 359–404.
    Search in Google Scholar
  36. 35a. Gold, L. S. and E. Zeiger: Handbook of carcinogenic potency and genotoxicity databases; CRC Press, Boca Raton, FL (1997); see also Gold, L. S.: Carcinogenic Potency Database (CPDB) http://potency.berkeley.edu/, accessed 05/03/2011.
    Search in Google Scholar
  37. 36. Green, C. R.: Some relationships between tobacco leaf and smoke composition; in: Recent advances in the chemical composition of tobacco and tobacco smoke, edited by J. L. McKenzie, R. M. Ikeda, T. R. Terrill, D. G. Vickroy, and D. B. Walters, Proc. Am. Chem. Soc. Symp., New Orleans, LA (1977) 426–470.
    Search in Google Scholar
  38. 37. Green, C. R.: Tobacco and smoke chemistry; RJRT presentation, March 21, 1984, see www.rjrtdocs. com, 512094044-4155, 504890559-0670, accessed 05/03/ 2011.
    Search in Google Scholar
  39. 38. Green, C. R.: Book review: The chemical components of tobacco and tobacco smoke (Alan Rodgman and Thomas A. Perfetti, CRC Press, Taylor and Francis Group, Boca Raton, Florida, 2008, 1836 pages); Beitr. Tabakforsch. Int. 23 (2009) 227–230.
    Search in Google Scholar
  40. 39. Grob, K.: High resolution g. c. analysis of cigarette smoke; Chem. Ind. 6 (1973) 248–252.
    Search in Google Scholar
  41. 40. Heller, S. R., Editor, The Beilstein Online Database – Implementation, content, and retrieval; ACS Sympo-sium Series #436, American Chemical Society, Washington, DC, 1990.10.1021/bk-1990-0436
    Search in Google Scholar
  42. 41. Hlubucek, J. R., A. J. Aasen, S. -O. Almqvist, and C. R. Enzell: Tobacco chemistry. 21. Three new volatile tobacco constituents of probable isoprenoid origin; Acta Chem. Scand. B27 (1973) 2232–2234.
    Search in Google Scholar
  43. 42. Hlubucek, J. R., A. J. Aasen, S. -O. Almqvist, and C. R. Enzell: Tobacco chemistry. 22. Structures and syn-theses of a nor- and a seco-terpenoid of the drimane series isolated from tobacco; Acta Chem. Scand. B28 (1974) 18–22.
    Search in Google Scholar
  44. 43. Hlubucek, J. R., A. J. Aasen, S. -O. Almqvist, and C. R. Enzell: Tobacco chemistry. 25. Two new drimane sesquiterpene alcohols from Greek Nicotiana tabacum L.; Acta Chem. Scand. B28 (1974) 289–294.
    Search in Google Scholar
  45. 44. Hlubucek, J. R., A. J. Aasen, B. Kimland, and C. R. Enzell: New volatile constituents of Greek Nicotiana tabacum L.; Phytochemistry 12 (1973) 2555–2557.
    Search in Google Scholar
  46. 45. Hobbs, M. E.: Some physico-chemical aspects of cigarette smoke generation; CORESTA/TCRC Joint Conf., Williamsburg, VA, CORESTA Invited Papers (1972) 53–75.
    Search in Google Scholar
  47. 46. Hoffmann, D. and S. S. Hecht: Advances in tobacco carcinogenesis; in: Chemical carcinogenesis and mutagenesis, edited by C. S. Cooper and P. L. Grover, Springer-Verlag, London, UK (1990) 63–102.
    Search in Google Scholar
  48. 47. Hoffmann, D. and I. Hoffmann: [Chemical studies on tobacco smoke. C.] The changing cigarette: 1950–1995; J. Toxicol. Environ. Health 50 (1997) 307–364.
    Search in Google Scholar
  49. 48. Hoffmann, D. and I. Hoffmann: Tobacco smoke components. Letter to the Editor; Beitr. Tabakforsch. Int. 18 (1998) 49-52.
    Search in Google Scholar
  50. 49. Hoffmann, D. and I. Hoffmann: The changing ciga-rette: Chemical studies and bioassays; Chapter 5 in: Risks associated with smoking cigarettes with low machine-measured yields of tar and nicotine, NCI Smoking and tobacco control, Monograph 13, edited by D. M. Burns and N. L. Benowitz, Bethesda, MD (2001) 159-191.
    Search in Google Scholar
  51. 50. Hoffmann, D., I. Hoffmann, and K. El-Bayoumy: The less harmful cigarette: A controversial issue. A tribute to Ernst L. Wynder; Chem. Res. Toxicol. 14 (2001) 767-790.
    Search in Google Scholar
  52. 50a. International Agency for Research on Cancer (IARC): Evaluation of the carcinogenic risk to humans: Tobacco smoking; IARC, Lyon, France, IARC Monograph 38 (1986).
    Search in Google Scholar
  53. 51. Keith, C. H. and P. G. Tesh: Measurement of the total smoke issuing from a burning cigarette; Tob. Sci. 9 (1965) 61-64.
    Search in Google Scholar
  54. 52. Kimland, B., AJ. Aasen, S. -O. Almqvist, P. Arpino, and CR. Enzell: Volatile acids of sun-cured Greek Nicotiana tabacum; Phytochemistry 12 (1973) 835-847.
    Search in Google Scholar
  55. 53. Kimland, B., AJ. Aasen, and CR. Enzell: Tobacco chemistry. 12. Neutral volatile constituents of Greek tobacco; Acta Chem. Scand. 26 (1972) 1281-1284.
    Search in Google Scholar
  56. 54. Kimland, B., AJ. Aasen, and CR. Enzell: Tobacco chemistry. 10. Volatile neutral constituents of Greek tobacco; Acta Chem. Scand. 26 (1972) 2177-2184.
    Search in Google Scholar
  57. 55. Kimland, B., R. A. Appleton, AJ. Aasen, J. Roeraade, and CR. Enzell: Neutral oxygen-containing volatile constituents of Greek tobacco; Phytochemistry 11 (1972) 309-316.
    Search in Google Scholar
  58. 56. Kosak, A. I.: The composition of tobacco smoke; Experientia 10 (1954) 69-71.
    Search in Google Scholar
  59. 57. Laurene, A. H.: Personal communication to A. R. (1965).
    Search in Google Scholar
  60. 58. Lazar, P., I. Chouroulinkov, C. Libermann, and M. Guerin: Amounts of 3,4-benzpyrene (3,4-BP) in cigarette smoke condensates and carcinogenicity; 9th Internat. Cancer Cong., Tokyo, Japan (1966).
    Search in Google Scholar
  61. 59. Lazar, P., I. Chouroulinkov, C. Libermann, and M. Guerin: Benzo[a]pyrene content and carcinogenicity of cigarette smoke condensate: Results of short-term and long-term tests; J. Natl. Cancer Inst. 37 (1966) 573-579.
    Search in Google Scholar
  62. 60. Leffingwell, J. C: Nitrogen components of leaf and their relationship to smoking quality and aroma; Recent Adv. Tob. Sci. 2 (1976) 1–31.
    Search in Google Scholar
  63. 61. Leffingwell, J. C: Leaf chemistry. A. Basic chemical constituents of tobacco leaf and differences among tobacco types; Chapter 8A in: Tobacco: Production, chemistry and technology, edited by D. L. Davis and M. T. Nielsen, Blackwell Science, Oxford, UK (1999) 265-284; Chemical constituents of tobacco leaf and differences among tobacco types; Leffingwell Reports. 1 (2001) 1-56.
    Search in Google Scholar
  64. 62. Leffingwell, J. C. and E. D. Alford: Phenolic aroma constituents of Kentucky fire cured tobacco; 52nd Tobacco Science Research Conference, Program Booklet and Abstracts, Vol. 52, Paper No. 17, 1998, p. 23, see www.leffingwell. com/firecured. htm, accessed 05/03/2011.
    Search in Google Scholar
  65. 63. Leffingwell, J. C. and E. D. Alford: Volatile constituents of Perique tobacco; Electronic J. Environ. Agr. Food Chem. 4 (2005) 899-915.
    Search in Google Scholar
  66. 64. Leffingwell, J. C. and D. Leffingwell: TCRC Sympo-sium: Chemical and sensory aspects of tobacco flavor - An overview; Recent Adv. Tob. Sci. 14 (1988) 169-218.
    Search in Google Scholar
  67. 65. Leffingwell, J. C, HJ. Young, and E. Bernasek: Tobacco flavoring for smoking products; R. J. Reynolds Tobacco Company, Winston-Salem, NC (1972), see www.rjrtdocs. com 509248328 -8365, accessed 05/03/2011.
    Search in Google Scholar
  68. 66. Lloyd, R. A., C. W. Miller, D. L. Roberts, J. A. Giles, J. P. Dickerson, N. H. Nelson, CE. Rix, and P. H. Ayers: Flue-cured tobacco flavor. I. Essence and essential oil components; CORESTA 1974 Symp., Montreux, Switzerland (1974); Tob. Sci. 20 (1976) 40-48.
    Search in Google Scholar
  69. 67. Norman, V.: An overview of the vapor phase, semivolatile and nonvolatile components of cigarette smoke; Recent Adv. Tob. Sci. 3 (1977) 28-58.
    Search in Google Scholar
  70. 68. National Research Council (NRC): Complex mixtures: Methods for in vivo toxicity testing; National Academy Press, Washington, DC, 1988.
    Search in Google Scholar
  71. 69. Occupational Safety and Health Administration (OSHA): Indoor air quality; Fed. Reg. 59 (No. 65) (1994) 15968-16039.
    Search in Google Scholar
  72. 69a. Opperman, C, S. Lommel, and the Tobacco Genome Initiative Group: The Tobacco Genome Initiative: Gene discovery, data mining, and implications to plant biology; Recent Adv. Tob. Sci. 33 (2007) 5-14.
    Search in Google Scholar
  73. 70. Osborne, J. S., S. Adamek, and M. E. Hobbs: Some components of gas phase of cigarette smoke; Anal. Chem. 28 (1956) 211-215.
    Search in Google Scholar
  74. 71. Roberts, D. L.: Natural tobacco flavor; Recent Adv. Tob. Sci. 14 (1988) 49-81.
    Search in Google Scholar
  75. 72. Roberts, D. L. and W. A. Rohde: Isolation and identifi-cation of flavor components of burley tobacco; Tob. Sci. 16 (1972) 107-112.
    Search in Google Scholar
  76. 73. Rodgman, A.: The composition of cigarette smoke: Problems with lists of tumorigens; Beitr. Tabakforsch. Int. 20 (2003) 402-437.
    Search in Google Scholar
  77. 74. Rodgman, A. and L. C Cook: The composition of cigarette smoke; Presented at Sigma Xi Meeting, Wake Forest University, Winston-Salem, NC 17 March, 1965, see www.rjrtdocs. com 501521599-1606, accessed 05/03/2011; the American Chemical Society Section Meeting, Columbus, GA, 2 May 1968, and the Chemistry Club, Chemistry Department, Columbus College, Columbus, GA, 2 May 1968, see www.rjrtdocs. com 501521608 -1615, accessed 05/03/2011; and the Central North Carolina Section Meeting, American Chemical Society, Greensboro, NC, 14 October 1969, for presentation text and slides, see www.rjrtdocs. com 501521658 -1700, accessed 05/03/2011.
    Search in Google Scholar
  78. 75. Rodgman, A. and CR. Green: Toxic chemicals in cigarette mainstream smoke hazard and hoopla; in: Cigarette risk and the potential for risk reduction; Proceedings of the 2002 CORESTA Congress, New Orleans, LA, pp. 2-52, see www.rjrtdocs. com 526909637 -9687, accessed 05/03/2011; Beitr. Tabakforsch. Int. 20 (2003) 481–545.
    Search in Google Scholar
  79. 76. Rodgman, A. and T. A. Perfetti: The chemical compo-nents of tobacco and tobacco smoke; CRC Press, Boca Raton, FL (2008).10.1201/9781420078848
    Search in Google Scholar
  80. 77. Rodgman, A., C. J. Smith, and T. A. Perfetti: The composition of cigarette smoke: A retrospective, with emphasis on polycyclic components; Human Exptl. Toxicol. 19 (2000) 573–595.
    Search in Google Scholar
  81. 78. Roe, F. J. C.: Role of 3,4-benzopyrene in carcino-genesis by tobacco smoke condensate; Nature 194 (1962) 1089–1090.
    Search in Google Scholar
  82. 79. Roe, F. J. C.: Role of 3,4-benzopyrene in carcino-genesis by tobacco smoke condensate. Acta Unio Internat Contra Cancrum 19 (1963) 730.
    Search in Google Scholar
  83. 80. Schlotzhauer, W. S., E. B. Higman, and I. Schmeltz: Products from pyrolysis of tobacco extracts; in: The chemistry of tobacco and tobacco smoke, edited by I. Schmeltz, Plenum Publishing Corp., New York, NY (1972) 69.10.1007/978-1-4757-0462-4_5
    Search in Google Scholar
  84. 81. Schumacher, J. N.: Maryland tobacco; R&DR, 1982, No. 4, February 12, see www.rjrtdocs. com 501006126 -6151, accessed 05/03/2011; Flavor composition of Maryland tobacco; 36th Tobacco Chemists’ Research Conference, Program Booklet and Abstracts, Vol. 36, Paper No. 25, 1982, p. 13; CORESTA 1982 Symp., Winston-Salem, NC, CORESTA Inf. Bull., Spec. Edition 1982: Paper S11, 21–22; Beitr. Tabakforsch. Int. 12 (1982) 271–278.
    Search in Google Scholar
  85. 82. Schumacher, J. N. and L. L. Vestal: Turkish tobacco. Isolation and identification of some components of the essential oil of Turkish tobacco dust; RDR, 1962, No. 18, June 25, see www.rjrtdocs. com 500938952-8981, accessed 05/03/2011.
    Search in Google Scholar
  86. 83. Schumacher, J. N. and L. L. Vestal: Isolation and identification of some components of Turkish tobacco; 27th Tobacco Chemists’ Research Conference, Program Booklet and Abstracts, Vol. 27, Paper No. 47, 1973, p. 31; Tob. Sci. 18 (1974) 43–48.
    Search in Google Scholar
  87. 84. Shear, M. J. and J. Leiter: Studies in carcinogenesis. XVI. Production of subcutaneous tumors in mice by miscellaneous polycyclic compounds; J. Natl. Cancer Inst. 2 (1941) 241–258.
    Search in Google Scholar
  88. 85. Stedman, R. L: The chemical composition of tobacco and tobacco smoke; Chem. Rev. 68 (1968) 153–207.
    Search in Google Scholar
  89. 86. Stepanov, I., P. W. Villalta, A. Knezevich, J. Jensen, D. Hatsukami and S. S. Hecht: Analysis of 23 poly-cyclic aromatic hydrocarbons in smokeless tobacco by gas chromatography-mass spectrometry; Chem. Res. Toxicol. 23 (2010) 66–73.
    Search in Google Scholar
  90. 87. Tso, T. C.: Production, physiology, and biochemistry of tobacco plant; Ideals, Inc., Beltsville, MD (1990).
    Search in Google Scholar
  91. 88. Tso, T. C.: Production, physiology, and biochemistry of tobacco plant; Ideals, Inc., Beltsville, MD (1990), see Chapter 27, Table 27. 1, Compounds reported in leaf tobacco, pp. 596–600.
    Search in Google Scholar
  92. 89. US Public Health Service (USPHS): Reducing the health consequences of smoking. 25 Years of progress. A report of the Surgeon General; DHHS Publ. No. (PHS) 89-8411 (1989).
    Search in Google Scholar
  93. 90. Wakeham, H.: Recent trends in tobacco and tobacco smoke research; Symposium on the Composition of Tobacco and Tobacco Smoke, Am. Chem. Soc. Mtg., Washington, DC (1971); in: The chemistry of tobacco and tobacco smoke, edited by I. Schmeltz, Plenum Press, New York, NY (1972) 1–20.
    Search in Google Scholar
  94. 91. Weeks, W. W.: Chemistry of tobacco constituents influencing flavor and aroma; Recent Adv. Tob. Sci. 11 (1985) 175–200.
    Search in Google Scholar
  95. 92. Williams, R. W. and Science Information Division, Research and Development: Constituents reported in tobacco and tobacco smoke; R. J. Reynolds Tobacco Company, Winston-Salem, NC, 1997, pp. 1–134; In-house data base for chemical compounds isolated from tobacco and tobacco smoke/aerosol; R&DM, 1989, No. 30, February 2, see www.rjrtdocs. com 508885321 -5341, accessed 05/03/2011; see also www.rjrtdocs. com 517550972 -1193, accessed 05/03/2011; see also http://legacy.library.ucsf.edu/tid/aqf91c00, accessed 05/03/2011; Chemical compounds isolated from tobacco and tobacco smoke/aerosol. II. CHEM database system modifications; R&DM, 1990, No. 9, January 29, see www.rjrtdocs.com 508381184-1197, accessed 05/03/2011.
    Search in Google Scholar
DOI: https://doi.org/10.2478/cttr-2013-0902 | Journal eISSN: 2719-9509
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Language: English
Page range: 215 - 232
Submitted on: Oct 9, 2010
Accepted on: Jan 27, 2011
Published on: Dec 30, 2014
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© 2014 TA Perfetti, A Rodgman, published by Institut für Tabakforschung GmbH
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