References
- 1. Lehmann, K.B.: Untersuchungen im Rauch des Tabaks [Investigation of the smoke from tobacco]; München med. Wochenschrift LV (1908) 723–725.
- 2. Isaac, R.F. and M.J. Rand: Cigarette smoking and plas-ma levels of nicotine; Nature 236 (1972) 308–310.
- 3. McAughey, J.J., D.K. Knight, A. Black, and C.J. Dickens: Environmental tobacco smoke retention in humans from measurements of exhaled smoke compo-sition; Inhal. Toxicol. 6 (1994) 615–631.
- 4. Armitage, A.K., C.T. Dollery, C.F. George, T.H. House-man, P.J. Lewis, and D.M. Turner: Absorbtion and metabolism of nicotine from cigarettes; Brit. Med. J. 4 (1975) 313–316.
- 5. Gori, G.B., N.L. Benowitz, and C.J. Lynch: Mouth versus deep airways absorption of nicotine in cigarette smokers; Pharmacol. Biochem. and Behavior, 25 (1986) 1181–1184.
- 6. Armitage, A.K., M. Dixon, B.E. Frost, D.C. Mariner, and N.M. Sinclair: The effect of tobacco blend additives on the retention of nicotine and solanesol in the human respiratory tract and on subsequent plasma nicotine concentrations during cigarette smoking; Chem. Res. Toxicol. 17 (2004) 537–544.
- 7. Armitage, A.K., M. Dixon, B.E. Frost, D.C. Mariner, and N.M. Sinclair: The effect of inhalation volume and breath-hold duration on the retention of nicotine and solanesol in the human respiratory tract and on subsequent plasma nicotine concentrations during cigarette smoking; Beitr. Tabakforsch. Int. 21 (2004) 240–249.
- 8. Bernstein, D.M.: A review of the influence of particle size, puff volume, and inhalation pattern on the deposition of cigarette smoke particles in the respiratory tract; Inhal. Toxicol. 16 (2004) 675–689.
- 9. Broday, D.M. and P.G. Georgopoulos: Growth and depo-sition of hygroscopic particulate matter in the human lung; Aerosol. Sci. Tech. 34 (2001) 144–159.
- 10. Davies, C.N.: Deposition of inhaled particles in man; Chemistry and Industry (1974) 441–444.
- 11. Robinson, R.J. and C.P. Yu: Deposition of cigarette smoke particles in the human respiratory tract; Aerosol. Sci. Tech. 34 (2001) 202–215.
- 12. Hinds, W., M.W. First, G.L. Huber, and J.W. Shea: A method for measuring the deposition of cigarette smoke during smoking; Am. Ind. Hyg. Assoc. J. 44 (1983) 113–118.
- 13. Dalhamn, T., M-L. Edfors, and R. Rylander: Mouth absorption of various compounds in cigarette smoke; Arch. Environ. Health. 16 (1968) 831–835.
- 14. Dalhamn, T., M-L. Edfors, and R. Rylander: Retention of cigarette smoke components in human lungs; Arch. Environ. Health. 17 (1968) 746–748.
- 15. Baker, R.R., and M. Dixon: The retention of tobacco smoke constituents in the human respiratory tract; Inhal. Toxicol. 18 (2006) 255–294.
- 16. Laskowski, K.: Components of tobacco smoke and their absorption in the respiratory system of the smoker; Rocz. Pa½stw. Zak. Hig. [Ann. Natl. Inst. Hyg.] 2 (1951) 139–160.
- 17. Moldoveanu, S. C. and K.F. StCharles: Differences in the chemical composition of particulate phase of inhaled and exhaled cigarette smoke; Beitr. Tabakforsch. Int. 22 (2006) 290–302.
- 18. Moldoveanu, S.C, W. Coleman III, J.M. Wilkins: Deter-mination of carbonyl compounds in exhaled cigarette smoke; Beitr. Tabakforsch. Int. 23 (2008) accepted for publication.
- 19. Thomkins, B.A., R.A. Jenkins, W.H. Griest, R.R. Reagan, and S.K. Holladay: Liquid chromatographic determination of benzo[a]pyrene in total particulate matter of cigarette; J. Assoc. Off. Anal. Chem. 68 (1985) 935–940.
- 20. Risner, C.H.: The determination of benzo[a]pyrene in the total particulate matter of cigarette smoke; J. Chromatogr. Sci., 26 (1988) 113–120.
- 21. Risner, C.H.: The determination of benzo[a]pyrene and benzo[a]anthracene in mainstream and sidestream smoke of Kentucky reference cigarette 1R4F and a ciga-rette which heats but not burn tobacco: A comparison; Beitr. Tabakforsch. Int. 15 (1991) 11–17.
- 22. Dumont, J., F. Laroque-Lazure, and C. Iorio: An alter-native isolation process for the subsequent determination of benzo[a]pyrene in total particulate matter of cigarette smoke; J. Chromatogr. Sci., 31 (1993) 371–374.
- 23. Evans, W. H., N.C. Thomas, M.C. Boardman, S.J. Nash, and J. Stephen: Relationship of polycyclic aromatic hydrocarbon yields with particular matter (water and nicotine free) yields in mainstream and sidestream cigarette smoke; Sci. Total Environ. 136 (1993) 101–109.
- 24. Borgerding, M.F., J.A. Bodnar, H.L. Chung, P.P. Mangan, C.C. Mossison, C.H. Risner, J.C. Rogers, D.F. Simmons, M.S. Uhrig, F.N. Wendelboe, D.E. Wingate, and L.S. Winkler: Chemical and biological studies of a new cigarette that primarily heats tobacco, Part I. Chemical composition of mainstream smoke; Food Chem. Toxicol. 36 (1997) 169–182.
- 25. Chepiga, T.A., M.J. Morton, P.A. Murphy, J.T. Avalos, B.R. Bombick, D.J. Doolittle, M.F. Borgeding, and J.E. Swauger: A comparison of mainstream and sidestream smoke chemistry and mutagenicity of a representative sample of the US cigarette market with two Kentucky reference cigarettes (K1R4F and K1R5F); Food Chem. Toxicol. 38 (2000) 949–962.
- 26. Gmeiner, G., G. Stehlik, and H. Tausch: Determination of seventeen polycyclic aromatic hydrocarbons in tobacco smoke condensate; J. Chromatogr. A 767 (1997) 163–169.
- 27. Forehand, J.B., G.L. Dooly, and S.C. Moldoveanu: Ana-lysis of polycyclic aromatic hydrocarbons, phenols and aromatic amines in particulate phase cigarette smoke using simultaneous distillation and extraction as a sole sample cleanup step; J. Chromatogr. A 898 (2000) 111–124.
- 28. Zha, Q., N.X. Qian, and S.C. Moldoveanu: Analysis of polycyclic aromatic hydrocarbons in the particulate phase of cigarette smoke using a gas chromatographic-high resolution mass spectrometric technique, J. Chro-matogr. Sci. 40 (2002) 403–408.
- 29. Snook, M.E., R.F. Severson, R.F. Arrendale, H.C. Hig-man, and O.T. Chortyk: Multi-alkylated polynuclear aromatic hydrocarbons on tobacco smoke: Separation and Identification; Beitr. Tabakforsch. Int. 9 (1978) 222–247.
- 30. Pillsbury, H.C., C.C. Bright, K.J. O'Connor, and F.W. Irish: Tar and nicotine in cigarette smoke; J. Assoc. Off. Anal. Chem. 52 (1969) 458–462.
- 31. ISO 3308: Routine analytical cigarette smoking machine-definitions and standard conditions; International Organization for Standardization, Geneva, Switzerland, 1991 (E) pp. 1–3.
- 32. ISO 3402: Tobacco and tobacco products-atmosphere for conditioning and testing; International Organization for Standardization, Geneva, Switzerland, 1991, (E) pp. 1, 2.
- 33. ISO 4387: Cigarettes-determination of total and nicotine free dry particulate matter using a routine analytical smoking machine; International Organization for Stan-dardization, Geneva, Switzerland, 1991 (E) pp. 1–14.
- 34. ISO 10315: Cigarettes – determination of nicotine in smoke condensates – gas chromatographic method; International Organization for Standardization, Geneva, Switzerland, First Ed., 1991 (E).
- 35. St. Charles, F.K.: A robust method for determining con-sumer smoked cigarette yields from filter analytical data; 55th Tobacco Science Research Conference, Program Booklet and Abstracts, Vol. 55, Paper No. 92, 2001, pp. 73–74.
- 36. Bodnar, J.A., T.J. Collins, S.M. DeBusk, and M.F. Bor-gerding: Estimation of ‘tar’ and nicotine yields from individual cigarettes based on filter analysis after smoking; 58th Tobacco Science Research Conference, Program Booklet and Abstracts, Vol.58, Paper No. 8, 2004, p 25.
- 37. Chen, P.X. and S.C. Moldoveanu: Mainstream smoke chemical analysis for 2R4F Kentucky reference cigarette; Beitr. Tabakforsch. Int. 20 (2003) 448–458.
- 38. Moldoveanu, S.C. and V. David, Sample preparation in chromatography, Elsevier, Amsterdam 2002, pp. 81–84.10.1016/S0301-4770(02)80007-0
- 39. NIST/TRC Vapor pressure database: NIST standard reference database No 87. Standard reference data program, National Institute of Standards and Technology, Gaithersburg, MD 20899-2310.
- 40. Lyman J.W, W.F. Reehl, and D.H. Rosenblatt: Hand-book of chemical property estimation methods, ACS publication, Washington, DC, 1990, pp. 14–12 to 14–15.
- 41. Hansch, C., A. Leo, and D. Hoekman: Exploring QSAR: hydrophobic, electronic and steric constants; ACS Professional Reference Book, ACS, Washington, DC, 1995.
- 42. Broto, P., G. Moreau, and C. Vandycke: Molecular structure: perception, autocorrelation descriptor and SAR studies. System of atomic contribution for the calculation of the octanol/water partition coefficients; Eur. J. Med. Chem. -Chim. Theor. 19 (1984) 71–78.10.1016/0045-7949(84)90204-9
- 43. Kedem, O. and O Katchalsky: Thermodynamic analysis of the permeability of biological membranes to non-electrolyte; Biochim. Biophys. Acta 27 (1958) 229–246.
- 44. Guy, R.H.: Transdermal drug delivery; in: Comprehen-sive medicinal chemistry, edited by C. Hansch, Perga-mon, New York, 1995, Vol. 5, p 615.
- 45. Mariner D., M. McEwan, K. St. Charles, G. Krautter, and S. Appleton: Dose response relationship for urinary biomarkers of selected tobacco smoke constituents, 58th Tobacco Science Research Conference, Program Booklet and Abstracts, Vol.58, Paper 56, 2004, pp 55–56.
- 46. Hecht, S.S.: Human urinary carcinogen metabolites: biomarkers for investigating tobacco and cancer; Car-cinogenesis 23 (2002) 907–922.
- 47. Benowitz, N.L., P. Jacob III, J.T. Bernert, M. Wilson, L. Wang, F. Allen, and D. Dempsy: Carcinogen exposure during short-term switching from regular to “Light” cigarettes; Cancer Epidemiol. Biomarkers Prev. 14 (2005) 1376–1383.