Abstract
Knowledge of tobacco smoke composition grows rapidly by application of modern analytical methods. Hitherto, 181 nitrogen compounds are known comparable to 50 in 1959, comprising 24 aliphatic amines, 19 aromatic amines, 7 nonaromatic N-heterocyclic compounds, 26 pyridine bases, 6 other aromatic six-membered N-heterocyclic compounds, 2 pyrroles, 15 other aromatic five-membered N-heterocyclic compounds, 12 pyrazines, 16 tobacco alkaloids and compounds with two nitrogen rings, 15 amino acids, 16 nitriles, 6 nitroalkanes, some derivatives of nitrous acid, inorganic cyano compounds, nitrogen oxides, ammonia, and elemental nitrogen. The balance of all the nitrogen compounds in tobacco smoke condensate gives a hint at the occurrence of unknown neutral N-compounds.