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New tirapazamine derivatives protect cardiomyocytes from doxorubicin toxicity Cover

References

  1. 1. Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev. 2004; 56:185-229.10.1124/pr.56.2.615169927
  2. 2. Carvalho FS, Burgeiro A, Garcia R, Moreno AJ, Carvalho RA, Oliveira PJ. Doxorubicin-induced cardiotoxicity: from bioenergetic failure and cell death to cardiomyopathy. Med Res Rev. 2014;34: 106-35.10.1002/med.2128023494977
  3. 3. Floyd JD, Nguyen DT, Lobins RL, Bashir Q, Doll DC, Perry MC. Cardiotoxicity of cancer therapy. J Clin Oncol. 2005;23:7685-96.10.1200/JCO.2005.08.78916234530
  4. 4. Sardao, VA, Oliveira PJ, Holy J, Oliveira CR, Wallace KB. Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets. Cell Biol Toxicol. 2009;25:227-43.10.1007/s10565-008-9070-118386138
  5. 5. Torres VM, Simic VD. Doxorubicin-Induced Oxidative Injury of Cardiomyocytes – Do We Have Right Strategies for Prevention? In: M. Fiuza (ed). Cardiotoxicity of Oncologic Treatments. London: Intech Open; 2012.
  6. 6. Zhang J, Cui X, Yan Y, Li M, Yang Y, Wang J, et al. Research progress of cardioprotective agents for prevention of anthracycline cardiotoxicity. Am J Transl Res. 2016;8:2862-75.
  7. 7. Hicks KO, Siim BG, Jaiswal JK, Pruijn FB, Fraser AM, Patel R, et al. Pharmacokinetic/pharmacodynamic modelling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumors. Clin Cancer Res. 2010;16:4946-57.10.1158/1078-0432.CCR-10-1439339097120732963
  8. 8. Hong B, Lui VWY, Hui EP, Ng MH, Cheng, SH, Sung FL, et al. Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation. Invest New Drugs. 2011;29:401-10.10.1007/s10637-009-9356-z20013349
  9. 9. Reddy SB, Williamson SK. Tirapazamine: a novel agent targeting hypoxic tumor cells. Expert Opin Investig Drugs. 2009;18:77-87.10.1517/1354378080256725019053884
  10. 10. Sliwinska J, Dudka J, Korga A, Burdan F, Matysiak W, Jodlowska-Jedrych B, et al. Tirapazamine-doxorubicin interaction referring to heart oxidative stress and Ca2+ balance protein levels. Oxid Med Cell Longev. 2012:article ID 890826.10.1155/2012/890826336221122666522
  11. 11. Minotti G, Licata S, Saponiero A, Menna P, Calafiore AM, Di Giammarco G, et al. Anthracycline metabolism and toxicity in human myocardium: comparisons between doxorubicin, epirubicin and a novel disaccharide analogue with reduced formation and [4Fe-4S]-reactivity of its secondary alcohol metabolite. Chem Res Toxicol. 2000;13:1336-41.10.1021/tx000143z11123976
  12. 12. Halliwell B. Reactive species and antioxidants. Redox biology is a fundamental theme of aerobic life. Plant Physiol. 2006;141:312-2210.1104/pp.106.077073147543116760481
  13. 13. Berthiaume JM, Wallace KB. Adriamycin-induced oxidative mitochondrial cardiotoxicity. Cell Biol Toxicol. 2007;23:15-25.10.1007/s10565-006-0140-y17009097
  14. 14. Wouters BG, Delahoussaye YM, Evans JW, Birrell GW, Dorie MJ, Wang J et al. Mitochondrial dysfunction after aerobic exposure to the hypoxic cytotoxin tirapazamine. Cancer Res. 2001;61:145-52.
  15. 15. Matysiak W, Dudka J, Korga A, Zięba J, Syroka I, Dawidek-Pietryka K, et al. Effect of tirapazamine on oxidative stress and metabolic parameters in skeletal muscle of rats treated with classic anticancer drugs. Ann UMC Sec DDD. 2010;XXIII(1):12.
  16. 16. Ross MF, Kelso GF, Blaikie FH, James AM, Cochemé HM, Filipovska A, et al. Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology. Biochemistry (Mosc). 2005;70:222-30.10.1007/s10541-005-0104-515807662
DOI: https://doi.org/10.2478/cipms-2020-0001 | Journal eISSN: 2300-6676 | Journal ISSN: 2084-980X
Language: English
Page range: 1 - 5
Submitted on: Jun 13, 2019
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Accepted on: Sep 6, 2020
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Published on: Mar 27, 2020
Published by: Sciendo
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 Agnieszka Korga, Magdalena Iwan, Dariusz Matosiuk, Marzena Rzadkowska, Elzbieta Szacon, Ewelina Humeniuk, Marcin Sysa, Marta Ostrowska, Jaroslaw Dudka, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.