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Herbal therapy with application of Brazilian peppertree and Cat’s claw Cover

Herbal therapy with application of Brazilian peppertree and Cat’s claw

Open Access
|Sep 2025

Figures & Tables

Examples of benefits of Brazilian peppertree fruit_

BenefitsKeypointReference
Antimycobacterial activityIts flavonoids are responsible for antimycobacterial activity.Bernardes et al., 2014
Antibacterial activity
  • – Its tetrahydroamentoflavone revealed the highest antibacterial activity.

  • – Its bioflavonoids showed inhibition biofilm formation, and activity against planktonic cells.

  • – Linkage of flavonoids and degree of saturation of the C-ring identified due to its antibacterial activity.

Linden et al., 2020
α-phellandrene and α-pinene showed promising antibacterial activity.Salem et al., 2018
Its essential oil promoted cell damage in all tested bacteria, and promoted the leakage of macromolecules and small ions from bacterial cells.Dannenberg et al., 2019
Antimicrobial activityIts bioflavonoids have significant role in the response to microbial infections.Linden et al., 2020
Antifungal activityIt showed antifungal activity against Candida albicans.Alves et al., 2013
Antiallergic activityIts ethyl acetate faction showed antiallergic activity.Cavalher-Machado et al., 2008
Anticancer activityIt has shown anticancer activity and it was found effective in reducing the number of lung tumor nodules.
  • Matsuo et al., 2011

  • Silva et al., 2019

Antitumor activityIts extracts showed potential activity against tumor cell lines such as glioma and kidney.Silva et al., 2017
Antidiabetic activityIts extract showed antidiabetic activities because of glycosylated flavonols, gallotannins, and gallic acid.Rocha et al., 2019
Antiinflammatory activityIts extracts inhibited cytokine, leukocyte migration and chemokine production which makes it suitable for the treatment of inflammatory diseases.
  • Fedel-Miyasato et al., 2014

  • Rosas et al., 2015

  • Feriani et al., 2021

Antihypertensive activityIt has shown antihypertensive activity due to its phenolic components.Gloria et al., 2017
Antioxidant activityIt has shown high antioxidant potential due to its high tannins, anthocyanins, flavonoids, and phenolic acids.
  • Sassi et al., 2020

  • Barreira et al., 2023

Its fruit can be considered as a natural food additive due to its high antioxidant activity.
  • Tlili et al., 2018

  • De Oliveira et al., 2020a,b

  • Oliveira et al., 2020b

It is recommended as an alternative to replace synthetic antioxidants in processed food.Vieira et al., 2023
Its essential oil reduced contents of primary and secondary ingredients of lipoxidation, and the essential oil of ripe fruits showed anti- oxidant activity in cheese.Dannenberg et al., 2016
Insecticidal activityIts seed flour is toxic to the cowpea weevil (Callosobruchus maculatus (F.), larval development, as the seeds are rich in proteins such as chitinases, lipoxygenase, glycinin, 7S globulins, and others.Oliveira et al., 2022
Its essential oil shows high insecticidal activity against Phthorimaea operculella and Spodoptera littoralis.Ennigrou et al., 2017
Its fruit essential oil can be used for control of castor bean white-fly (Trialeurodes ricini Misra), and sweet potato whitefly (Bemisia tabaci Gennadius).Hussein et al., 2017
The essential oil of its fruits showed insecitidal activity against Trialeurodes ricini, Bemisia tabaci, Culex pipiens, and Rhyzopertha dominica.
  • Manrique et al., 2008

  • Camaroti et al., 2018

  • Bernardi et al., 2024

Its essential oil can be used against cowpea weevil (Callosobruchus maculatus Fabricius).Torre et al., 2024

Some of the most important health benefits of Uncaria tomentosa_

Pharmacological benefitsKeypointReference
Anticancer activityIt contains different types of pentacyclic oxindole alkaloids which have shown anticancer activities against breast cancer, cervical, thyroid, and bladder cells.
  • Riva et al., 2001

  • Rinner et al., 2009

  • Pilarski et al., 2010

Its extracts decrease the infiltration of T cells into the tumours, and reduced angiogenic markers in cancer cells.Zari et al., 2021
It has shown antiproliferative effect against different cell lines, such as neuroblastoma, leukaemia, acute lymphoblastic, breast cancer, promyelocytic leukaemia, and glioma.
  • Akesson et al., 2003a,b

  • Cheng et al., 2007


Antineoplastic activityIt has immunostimulatory and antitumor activity due to its oxindole alkaloids content.Piscoya et al., 2001

Antioxidant activityIt has antioxidant activity, and it can be used for treatment of chronic inflammatory diseases.
  • Sandoval et al., 2000

  • Piscoya et al., 2001

  • Araya-Sibaja et al., 2022

It was discovered to protect against oxidative stress in human erythrocytes.Sandoval et al., 2002
It has also the significant cytoprotective effect due to its ability to interact with the injurious oxidant.Sandoval et al., 2000

Antiinflammatory activityIt has antiinflammatory activity due to its NF-kB inhibition.Allen-Hall et al., 2010

Antimicrobial activityIt shows antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis.Ccahuana-Vasquez et al., 2007

Antiviral activityIt has been examined as a binding factor for the ACE2 receptor at the site where Covid-19 spike protein binds.Yepes-Perez et al., 2020
Its extracted alkaloid is useful against dengue virus-2 (DENV) in vitro.
  • Reis et al., 2008

  • Lima-Junior et al., 2013


Skin health and wound dressing materialAlginate films with its extract could be applied as wound dressings materials.Elgegren et al., 2021
DOI: https://doi.org/10.2478/cag-2025-0009 | Journal eISSN: 3071-740X | Journal ISSN: 2081-2787
Language: English
Page range: 106 - 117
Submitted on: Jun 30, 2025
Accepted on: Aug 28, 2025
Published on: Sep 16, 2025
Published by: Institute of Soil Science and Plant Cultivation
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Mohamad Hesam Shahrajabian, published by Institute of Soil Science and Plant Cultivation
This work is licensed under the Creative Commons Attribution 4.0 License.