Skip to main content
Have a personal or library account? Click to login
Transcriptomic profiling of peripheral blood nucleated cells in dogs with and without clinical signs of chronic mitral valve disease Cover

Transcriptomic profiling of peripheral blood nucleated cells in dogs with and without clinical signs of chronic mitral valve disease

Journal of Veterinary Research
Volume 58 (2014): Issue 1 (March 2014)
By: ,  ,  ,   and    
Open Access
|Mar 2014
References

References

  1. 1. Atkins C., Bonagura J., Ettinger S., Fox P., Gordon S., Haggstrom J., Hamlin R., Keene B., Luis-Fuentes V., Stepien R.: ACVIM consensus statement, guidelines for the diagnosis and treatment of canine chronic valvular heart disease. J Vet Intern Med 2009, 23, 1142-1150.
    Open DOISearch in Google Scholar
  2. 2. Aupperle H., Thielebein J., Kiefer B., Marz I., Dinges G., Schoon H.A.: An immunohistchemical study of the role of matrix metalloproteinases and their tissue inhibitor in chronic mitral valvular diease (valvular endocardiosis) in dogs. Vet J 2009, 180, 88-94.
    Open DOISearch in Google Scholar
  3. 3. Aupperle H., Thielebein J., Kiefer B., Marz I., Dinges G., Schoon H.A., Schubert A.: Expression of genes encoding matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in normal and diseased canine mitral valves. J Comp Pathol 2009, 140, 271-277.
    Open DOISearch in Google Scholar
  4. 4. Disatian S., Ehrhart E.J., Zimmerman S., Orton E.C.: Interstitial cells from dogs with naturally occurring myxomatous mitral valve disease undergo phenotype transformation. J Heart Valve Dis 2008, 17, 402-412.
    Search in Google Scholar
  5. 5. Garncarz M., Jank M., Łój M., Parzeniecka-Jaworska M.: A retrospective study of clinical signs and epidemiology of chronic valve disease in a group of 207 Dachshunds in Poland. Acta Vet Scand 2013, 2013, 55, 52, doi:10.1186/1751-0147-55-52.
    Open DOISearch in Google Scholar
  6. 6. Garncarz M., Parzeniecka-Jaworska M., Łój M., Jank M. The use of peripheral blood nucleated cells for the transcriptomic characterization of heart disease in dogs. In: BSAVA Congress Proceedings. Gloucester 2013, 580.
    Search in Google Scholar
  7. 7. Hautala N., Tokola H., Luodonpää M., Puhakka J., Romppanen H., Vuolteenaho O., Ruskoaho H.: Pressure overload increases GATA4 binding activity via endothelin-1. Circulation 2001, 103, 730-735.
    Open DOISearch in Google Scholar
  8. 8. Kiczak L., Tomaszek A., Bania J., Pasławska U., Zacharski M., Noszczyk-Nowak A., Janiszewski A., Skrzypczak P., Ardehali H., Jankowska E.A., Ponikowski P.: Expression and complex formation of MMP9, MMP2, NGAL, and TIMP1 in porcine myocardium but not in skeletal muscles in male pigs with tachycardia-induced systolic heart failure. BioMed Res Int, vol. 2013, Article ID 283856, doi: 10.1155/2013/283856.
    Open DOISearch in Google Scholar
  9. 9. Lee J.S., Pak S.I., Hyun C.: Calcium reuptake related genes as a cardiac biomarker in dogs with chronic mitral valvular insufficiency. J Vet Intern Med 2009, 23, 832-839.
    Open DOISearch in Google Scholar
  10. 10. Lemon D.D., Horn T.R., Cavasin M.A., Jeong M.Y., Haubold K.R., Long Carlin S.L., Irwin D.C., McCune S.A., Chung E., Leinwand L.A., McKinsey T.A.: Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. J Mol Cell Cardiol 2011, 51, 41-50.
    Open DOISearch in Google Scholar
  11. 11. Liu P.Y., Death A.K., Handelsman D.J.: Androgens and cardiovascular disease. Endocr Rev 2003, 24, 313-340.
    Open DOISearch in Google Scholar
  12. 12. Łój M., Garncarz M., Jank M.: Genomic and genetic aspects of heart failure in dogs - a review. Acta Vet Hung 2012, 60, 17-26.
    Open DOISearch in Google Scholar
  13. 13. Moon H.S., Choi E., Hyun C.: The cardiac sodium-calcium exchanger gene (NCX-1) is a potential canine cardiac biomarker of chronic mitral valvular insufficiency. J Vet Intern Med 2008, 22, 1360-1365.
    Open DOISearch in Google Scholar
  14. 14. Musunuru K.: Cell-specific RNA-binding proteins in human disease. Trends Cardiovasc Med 2003, 13, 188-195.
    Open DOISearch in Google Scholar
  15. 15. Na S.J., Han S.H., Kim H.W., Hyun C.: The cardiac biomarker sodium-calcium Exchange (NCX-1) can differentiate between heart failure and renal failure: a comparative study of NCX-1 expression in dogs with chronic mitral valvular insufficiency and azotemia. J Vet Intern Med 2010, 24, 1383-1387.
    Open DOISearch in Google Scholar
  16. 16. Obayashi K., Miyagawa-Tomita S., Matsumoto H., Koyama H., Nakanishi T., Hirose H., Effects of transforming growth factor- ß3 and matrix metalloproteinase-3 on the pathogenesis of chronic mitral valvular disease in dogs. Am J Vet Res 2011, 72, 194-202.
    Open DOISearch in Google Scholar
  17. 17. Olsen L.H., Fredholm M., Pdersen H.D.: Epidemiology and inheritance of mitral valve prolapsed in Dachshunds. J Vet Intern Med 1999, 13, 448-456.
    Open DOISearch in Google Scholar
  18. 18. Oyama M.A., Chittur S.V.: Genomic expression patterns of mitral valve tissues from dogs with degenerative mitral valve disease. Am J Vet Res 2006, 67, 1307-1318.
    Open DOISearch in Google Scholar
  19. 19. Parker H.G., Kilroy-Glynn P.: Myxomatous mitral valve disease in dogs: does size matter? J Vet Cardiol 2012, 14, 19-29.
    Open DOISearch in Google Scholar
  20. 20. Pasławska U., Noszczyk-Nowak A., Nicpoń J.: An assessment of left ventricular systoli function with the use of a continuous Doppler imaging in dogs with spontaneous mitral regurgitation. A preliminary study. Bull Vet Inst Pulawy 2012, 56, 399-402.
    Open DOISearch in Google Scholar
  21. 21. Rush J.E. Canine chronic valvular heart disease: pathology and pathogenesis. In: Proceedings of the American College of Veterinary Internal Medicine - Cardiology Forum, 2004, 58.
    Search in Google Scholar
  22. 22. Stanley W.C., Recchia F.A., Lopaschuk G.D.: Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 2005, 85, 1093-1129.
    Open DOISearch in Google Scholar
  23. 23. Van Hemelrijck M., Garmo H., Holmberg L., Ingelsson E., Bratt O., Bill-Axelson A., Lambe M., Stattin P., Adolfsson J.: Absolute and relative risk of cardiovascular disease in men with prostate cancer: results from the population-based PCBaSe Sweden. J Clin Oncol 2010, 28, 3448-3456.
    Open DOISearch in Google Scholar
  24. 24. Van Loon J.E., Leebeek F.W.G., Deckers J.W., Dippel D.W.J., Poldermans D., Strachan D.P., Tang W., O’Donnell C.J., Smith N.L., De Maat M.P.M.: Effect of genetic variations in syntaxin-binding protein-5 and syntaxin-2 on von Willebrand factor concentration and cardiovascular risk. Circ Cardiovasc Genet 2010, 3, 507-512.
    Open DOISearch in Google Scholar
  25. 25. Zheng J., Chen Y., Pat B., Dell’italia L.A., Tillson M., Dillon A.R., Powell P.C., Shi K., Shah N., Denney T., Husain A., Dell’Italia L.J.: Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog. Circulation 2009, 119, 2086-2095.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/bvip-2014-0021 | Journal eISSN: 2450-8608 (formerly 2300-3235)
Journal RSS Feed
Language: English
Page range: 135 - 140
Published on: Mar 25, 2014
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Keywords:
dog,
transcriptomic profiling,
gene expression,
valve disease.
Related subjects:
Life sciences,
Molecular biology,
Microbiology and virology,
Life sciences, other,
Medicine,
Veterinary medicine

© 2014 Magdalena Garncarz, Magdalena Hulanicka, Marta Parzeniecka-Jaworska, Jacek Garncarz, Michał Jank, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 58 (2014): Issue 1 (March 2014)
Previous article
Next article