Expression of p16 (INK4a), cytokeratin 19, and Ki-67 in canine laryngeal squamous cell carcinoma

Małgorzata Kandefer-Gola; Rafał Ciaputa; Marcin Nowak; Janusz A. Madej

doi:10.2478/bvip-2013-0069

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Expression of p16 (INK4a), cytokeratin 19, and Ki-67 in canine laryngeal squamous cell carcinoma

Journal of Veterinary Research

Volume 57 (2013): Issue 3 (September 2013)

By: Małgorzata Kandefer-Gola, Rafał Ciaputa, Marcin Nowak and Janusz A. Madej

Open Access

|Sep 2013

Abstract

The study aimed at morphological and immunohistochemical characteristics of laryngeal squamous cell carcinomas and their metastases in canine lymph nodes and lungs. Tissue sections were stained using classical technique with haematoxylin and eosin. In addition, immunohistochemical studies were performed with p16, cytokeratin, and Ki-67 antibodies. An expression of all examined antigens was detected in laryngeal tumours, while in tumour metastases only expression of p16 protein and cytokeratin was demonstrated. The results pointed to higher proliferative potential of the primary tumour than of their metastases.

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Articles in this issue

DOI: https://doi.org/10.2478/bvip-2013-0069 | Journal eISSN: 2450-8608

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Language: English

Page range: 399 - 405

Published on: Sep 27, 2013

Published by: National Veterinary Research Institute in Pulawy

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

dog,

laryngeal squamous cell carcinoma,

Related subjects:

Microbiology and virology,

Life sciences, other,

Medicine,

Veterinary medicine

© 2013 Małgorzata Kandefer-Gola, Rafał Ciaputa, Marcin Nowak, Janusz A. Madej, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons License.

Volume 57 (2013): Issue 3 (September 2013)