Pituitary adenylate cyclase activating peptide-27 – like immunoreactive nerve fibers in the mucosal layer of canine gastrointestinal tract in physiology and during inflammatory bowel disease

Sławomir Gonkowski; Andrzej Rychlik; Jarosław Całka

doi:10.2478/bvip-2013-0065

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Pituitary adenylate cyclase activating peptide-27 – like immunoreactive nerve fibers in the mucosal layer of canine gastrointestinal tract in physiology and during inflammatory bowel disease

Journal of Veterinary Research

Volume 57 (2013): Issue 3 (September 2013)

By: Sławomir Gonkowski, Andrzej Rychlik and Jarosław Całka

Open Access

|Sep 2013

Abstract

Changes in the density of mucosal pituitary adenylate cyclase activating peptide-27 -like immunoreactive (PACAP-27 - LI) nerve fibers within various parts of the canine gastrointestinal (GI) tract during inflammatory bowel disease (IBD) were investigated. The distribution of nerves were studied, using a single-labelling immunofluorescence technique, in the mucosal layer of canine stomach, duodenum, jejunum, and descending colon. Canine IBD caused an increase in the density of PACAP- 27-LI mucosal nerves in all studied parts of GI tract. The results suggest that PACAP in the nervous system may be involved in pathological processes during IBD.

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Articles in this issue

DOI: https://doi.org/10.2478/bvip-2013-0065 | Journal eISSN: 2450-8608

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Language: English

Page range: 375 - 380

Published on: Sep 27, 2013

Published by: National Veterinary Research Institute in Pulawy

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

dogs,

pituitary adenylate cyclase activating peptide-27,

Related subjects:

Microbiology and virology,

Life sciences, other,

Medicine,

Veterinary medicine

© 2013 Sławomir Gonkowski, Andrzej Rychlik, Jarosław Całka, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons License.

Volume 57 (2013): Issue 3 (September 2013)