Figure 1.
Plasma samples that showed the presence of the T790M mutant allele variant
| SAMPLE NUMBER | NUMBER OF DROPLETS | WILD TYPE/MUTANT T790M | T790M MUTANT ALLELE FREQUENCY (%) | MUTANT CONC (COPIES/ML) |
|---|---|---|---|---|
| 3 | 6538 | 61/3 | 5 | 0.9 |
| 4 | 10038 | 7671/1634 | 12.3 | 209 |
| 6 | 8924 | 1534/8 | 0.5 | 0.8 |
| 8 | 12111 | 725/5 | 0.7 | 0.49 |
| 15 | 10891 | 480/4 | 0.8 | 0.43 |
| 18 | 8670 | 77/3 | 3.8 | 3 |
| 19 | 8015 | 210/7 | 3.3 | 1 |
| 20 | 12711 | 1428/2 | 0.1 | 0.28 |
| 34 | 7284 | 494/6 | 1.2 | 1 |
| 35 | 5775 | 577/25 | 4.1 | 5.1 |
| 36 | 14326 | 770/7 | 0.9 | 0.57 |
| 43 | 12788 | 632/16 | 2.5 | 1.5 |
| 44 | 12668 | 612/7 | 1.1 | 0.65 |
| 45 | 12789 | 536/18 | 3.3 | 1.7 |