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Association of Relative Telomere Length and Risk of High Human Papillomavirus Load in Cervical Epithelial Cells Cover

Association of Relative Telomere Length and Risk of High Human Papillomavirus Load in Cervical Epithelial Cells

By: A H Albosale and  E V Mashkina  
Open Access
|Jun 2022

Figures & Tables

Figure 1

The prevalence of high-risk HPV types in HPV-positive women.
The prevalence of high-risk HPV types in HPV-positive women.

Figure 2

Relative telomere length in control and HPV-positive women. Data are shown as box plots which represent a five-number summary of the data (the minimum, lower quartile, median, upper quartile, and maximum). A small circle indicates an outlier sample.
Relative telomere length in control and HPV-positive women. Data are shown as box plots which represent a five-number summary of the data (the minimum, lower quartile, median, upper quartile, and maximum). A small circle indicates an outlier sample.

The relative telomere lengths among the studied groups_

HPV groupControl group2−ΔΔCtp-value
NumberMean of T/S ± SDENumberMean of T/S ± SDE
501144.06 ± 64.085501571.21 ± 111.552.5925 ×10−1290.0014
HPV load 4-5lg
211035.12 ± 65.9264.1809 × 10−1620.0001
HPV load >5lg
291222.93 ± 98.0521.4454 × 10−1050.0217

The sequence of primers used in real-time PCR_

Primer/oligomerSequence
Primer Telo F5′- cgg-ttt-gtt-tgg-gtt-tgg-gtt-tgg-gtt-tgg-gtt-tgg-gtt-3′
Primer Telo R5′- ggc-ttg-cct-tac-cct-tac-cct-tac-cct-tac-cct-tac-cct-3′
Primer 36B4 F5′- cag-caa-gtg-gga-agg-tgt-aat-cc-3′
Primer 36B4 R5′-ccc-att-cta-tca-tca-acg-ggt-aca-a-3′
Language: English
Page range: 65 - 70
Published on: Jun 5, 2022
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2022 A H Albosale, E V Mashkina, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.