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Association of Relative Telomere Length and Risk of High Human Papillomavirus Load in Cervical Epithelial Cells

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Open Access
|Jun 2022

Figures & Tables

Figure 1

The prevalence of high-risk HPV types in HPV-positive women.
The prevalence of high-risk HPV types in HPV-positive women.

Figure 2

Relative telomere length in control and HPV-positive women. Data are shown as box plots which represent a five-number summary of the data (the minimum, lower quartile, median, upper quartile, and maximum). A small circle indicates an outlier sample.
Relative telomere length in control and HPV-positive women. Data are shown as box plots which represent a five-number summary of the data (the minimum, lower quartile, median, upper quartile, and maximum). A small circle indicates an outlier sample.

The relative telomere lengths among the studied groups_

HPV groupControl group2−ΔΔCtp-value
NumberMean of T/S ± SDENumberMean of T/S ± SDE
501144.06 ± 64.085501571.21 ± 111.552.5925 ×10−1290.0014
HPV load 4-5lg
211035.12 ± 65.9264.1809 × 10−1620.0001
HPV load >5lg
291222.93 ± 98.0521.4454 × 10−1050.0217

The sequence of primers used in real-time PCR_

Primer/oligomerSequence
Primer Telo F5′- cgg-ttt-gtt-tgg-gtt-tgg-gtt-tgg-gtt-tgg-gtt-tgg-gtt-3′
Primer Telo R5′- ggc-ttg-cct-tac-cct-tac-cct-tac-cct-tac-cct-tac-cct-3′
Primer 36B4 F5′- cag-caa-gtg-gga-agg-tgt-aat-cc-3′
Primer 36B4 R5′-ccc-att-cta-tca-tca-acg-ggt-aca-a-3′
Language: English
Page range: 65 - 70
Published on: Jun 5, 2022
Published by: Macedonian Academy of Sciences and Arts
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2022 A H Albosale, E V Mashkina, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.