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Frequencies of the MEFV Gene Mutations in Azerbaijan

Balkan Journal of Medical Genetics
Volume 24 (2021): Issue 2 (November 2021)
By:
Open Access
|Jun 2022

Figures & Tables

Figure 1

The MEFV gene mutations in 2.0% agarose gel electrophoresis: M-100 pb DNA ladder; 1-Normal; 2-M694V heterozygous mutations in exon 10 (212bp); 3-Normal; 4-M680I heterozygous mutations in exon 10 (220bp); 5-Normal; 6-M694I heterozygous mutations in exon 10 (184bp); 7-Normal; 8-R761H heterozygous mutations in exon 10 (247bp); 9-R761H homeozygous mutations in exon 10 (247bp); 10-mutant bands (184–247 bp)
The MEFV gene mutations in 2.0% agarose gel electrophoresis: M-100 pb DNA ladder; 1-Normal; 2-M694V heterozygous mutations in exon 10 (212bp); 3-Normal; 4-M680I heterozygous mutations in exon 10 (220bp); 5-Normal; 6-M694I heterozygous mutations in exon 10 (184bp); 7-Normal; 8-R761H heterozygous mutations in exon 10 (247bp); 9-R761H homeozygous mutations in exon 10 (247bp); 10-mutant bands (184–247 bp)

Figure 2

Electropherogram of changes in the nucleotide sequence of the heterozygous form of the mutation M694V (2080 (A> G)) found in the 10th exon of the MEFV gene.
Electropherogram of changes in the nucleotide sequence of the heterozygous form of the mutation M694V (2080 (A> G)) found in the 10th exon of the MEFV gene.

Gene frequencies of the studied mutations of the MEFV gene in the population of Azerbaijan in 2016–2021

№MutationLocationPatientsGene frequency (%)
11E148QExon 237.14%
22M680İExon 1024.78%
33R761HExon 101330.95%
44M694İExon 1037.14%
55M694VExon 101842.85%
66V726AExon 1037.14%
DOI: https://doi.org/10.2478/bjmg-2021-0017 | Journal eISSN: 2199-5761
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Language: English
Page range: 33 - 38
Published on: Jun 5, 2022
Published by: Macedonian Academy of Sciences and Arts
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Keywords:
Exon,
Familial Mediterranean fever (FMF),
Gene,
Inherited diseases,
Protein
Related subjects:
Medicine,
Basic medical science,
Basic medical science, other

© 2022 LS Huseynova, SN Mammadova, KAA Aliyeva, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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