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Evaluation of microRNA-124 expression in renal cell carcinoma Cover

Evaluation of microRNA-124 expression in renal cell carcinoma

Open Access
|Mar 2021

Figures & Tables

Table 1

The clinical parameters of patients.

ParametersMean ± SDMinimumMaximum
Age (years)58.70±10.263983
Height (cm)172.17±5.62163185
Weight (kg)81.03±7.6960100
BMI (kg/m2)27.52±2.9720.836.7
Waist circumference (cm)104.50±6.2995117
Total cholesterol (mg/dL)196.10±35.35139257
Triglycerides (mg/dL)159.07±36.2098225
HDL (mg/dL)43.40±3.143649
LDL (mg/dL)125.10±25.9868172
Neutrophils (cells/mm3)5.07±1.053.146.82
Lymphocytes (cells/mm3)1.64±0.181.321.99

[i] BMI: body mass index; HDL: high density lipoprotein;

LDL: low density lipoprotein.

Figure 1

The expression levels of miR-124 in tumor and control groups.

Table 2

The cycle threshold (Ct) values obtained for miR-124.

Tumor TissuesaHealthy Surrounding Tissuesb
ΔCT9.30±2.246.73±1.95
ΔΔCT2.72
2–ΔΔCT0.356
p Value<0.001

a Tumor group.

b Control group.

Table 3

The comparison of miR-124 expression in tumor and control groups with patient parameters.

Group2ΔCT (tumor group)2ΔCT (control group)
r Valuep Valuer Valuep Value
Age–0.140.47–0.090.63
Height0.890.320.0020.99
Weight–0.0810.67–0.0670.72
Body mass index–0.410.023–0.060.75
Waist circumference–0.0880.640.230.23
Total cholesterol–0.330.07–0.0850.65
Triglycerides–0.170.370.090.64
High density lipoprotein–0.050.79–0.210.26
Low density lipoprotein–0.250.18–0.080.68
Tumor stage–0.420.0220.160.39
Tumor diameter–0.470.0090.160.4
Neutrophil–0.4150.0230.710.71
Lymphocyte0.240.210.230.22
Visceral adiposity index–0.170.3650.10.56
Table 4

The correlation of miR-124 expression according to tumor stage with patient parameters.

StageT1T2T3
Group2ΔCT (tumor)2ΔCT (control)2ΔCT (tumor)2ΔCT (control)2ΔCT (tumor)2ΔCT (control)
r Valuep Valuer Valuep Valuer Valuep Valuer Valuep Valuer Valuep Valuer Valuep Value
BMI (kg/m2)–0.30.2120.230.34–0.540.27–0.430.4–0.90.037–0.90.037
Tumor dia (cm)–0.450.0550.070.780.810.05–0.0580.91–0.60.280.10.87
TC (mg/dL)–0.560.012–0.0560.82–0.480.330.540.26–0.50.39–0.90.037
NP (cells/mm3)–0.470.04–0.210.40.260.620.030.96–0.10.870.40.505

[i] BMI: body mass index; Tumor dia: tumor diameter; TC: total cholesterol; NP: neutrophil.

DOI: https://doi.org/10.2478/bjmg-2020-0029 | Journal eISSN: 2199-5761 (formerly 1311-0160) | Journal ISSN: 1311-0160
Language: English
Page range: 73 - 78
Published on: Mar 23, 2021
Published by: Macedonian Academy of Sciences and Arts
In partnership with: Paradigm Publishing Services

© 2021 B Çaykara, G Öztürk, H Alsaadoni, A Ötünçtemur, S Pençe, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.