Figure 1
The cycle threshold (Ct) values obtained for miR-124_
| Tumor Tissues Tumor group. | Healthy Surrounding Tissues Control group. | |
|---|---|---|
| ΔCT | 9.30±2.24 | 6.73±1.95 |
| ΔΔCT | 2.72 | |
| 2–ΔΔCT | 0.356 | |
| p Value | <0.001 | |
The correlation of miR-124 expression according to tumor stage with patient parameters_
| Stage | T1 | T2 | T3 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | 2–ΔCT (tumor) | 2–ΔCT (control) | 2–ΔCT (tumor) | 2–ΔCT (control) | 2–ΔCT (tumor) | 2–ΔCT (control) | ||||||
| r Value | p Value | r Value | p Value | r Value | p Value | r Value | p Value | r Value | p Value | r Value | p Value | |
| BMI (kg/m2) | –0.3 | 0.212 | 0.23 | 0.34 | –0.54 | 0.27 | –0.43 | 0.4 | –0.9 | 0.037 | –0.9 | 0.037 |
| Tumor dia (cm) | –0.45 | 0.055 | 0.07 | 0.78 | 0.81 | 0.05 | –0.058 | 0.91 | –0.6 | 0.28 | 0.1 | 0.87 |
| TC (mg/dL) | –0.56 | 0.012 | –0.056 | 0.82 | –0.48 | 0.33 | 0.54 | 0.26 | –0.5 | 0.39 | –0.9 | 0.037 |
| NP (cells/mm3) | –0.47 | 0.04 | –0.21 | 0.4 | 0.26 | 0.62 | 0.03 | 0.96 | –0.1 | 0.87 | 0.4 | 0.505 |
The clinical parameters of patients_
| Parameters | Mean ± SD | Minimum | Maximum |
|---|---|---|---|
| Age (years) | 58.70±10.26 | 39 | 83 |
| Height (cm) | 172.17±5.62 | 163 | 185 |
| Weight (kg) | 81.03±7.69 | 60 | 100 |
| BMI (kg/m2) | 27.52±2.97 | 20.8 | 36.7 |
| Waist circumference (cm) | 104.50±6.29 | 95 | 117 |
| Total cholesterol (mg/dL) | 196.10±35.35 | 139 | 257 |
| Triglycerides (mg/dL) | 159.07±36.20 | 98 | 225 |
| HDL (mg/dL) | 43.40±3.14 | 36 | 49 |
| LDL (mg/dL) | 125.10±25.98 | 68 | 172 |
| Neutrophils (cells/mm3) | 5.07±1.05 | 3.14 | 6.82 |
| Lymphocytes (cells/mm3) | 1.64±0.18 | 1.32 | 1.99 |
The comparison of miR-124 expression in tumor and control groups with patient parameters_
| Group | 2–ΔCT (tumor group) | 2–ΔCT (control group) | ||
|---|---|---|---|---|
| r Value | p Value | r Value | p Value | |
| Age | –0.14 | 0.47 | –0.09 | 0.63 |
| Height | 0.89 | 0.32 | 0.002 | 0.99 |
| Weight | –0.081 | 0.67 | –0.067 | 0.72 |
| Body mass index | –0.41 | 0.023 | –0.06 | 0.75 |
| Waist circumference | –0.088 | 0.64 | 0.23 | 0.23 |
| Total cholesterol | –0.33 | 0.07 | –0.085 | 0.65 |
| Triglycerides | –0.17 | 0.37 | 0.09 | 0.64 |
| High density lipoprotein | –0.05 | 0.79 | –0.21 | 0.26 |
| Low density lipoprotein | –0.25 | 0.18 | –0.08 | 0.68 |
| Tumor stage | –0.42 | 0.022 | 0.16 | 0.39 |
| Tumor diameter | –0.47 | 0.009 | 0.16 | 0.4 |
| Neutrophil | –0.415 | 0.023 | 0.71 | 0.71 |
| Lymphocyte | 0.24 | 0.21 | 0.23 | 0.22 |
| Visceral adiposity index | –0.17 | 0.365 | 0.1 | 0.56 |