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An investigation of the COMT gene Val158Met polymorphism in patients admitted to the emergency department because of synthetic cannabinoid use Cover

An investigation of the COMT gene Val158Met polymorphism in patients admitted to the emergency department because of synthetic cannabinoid use

Open Access
|Aug 2020

Figures & Tables

Figure 1

Sequence analysis image of the codon 158 region of the COMT gene. a) WT; b) homozygote p.Val158Met exchange; c) heterozygote p.Val158Met exchange.
Sequence analysis image of the codon 158 region of the COMT gene. a) WT; b) homozygote p.Val158Met exchange; c) heterozygote p.Val158Met exchange.

Demographic and genotypic distribution of patient and control groups_

Patients (n=49)Controls (n=50)
GenderMales48 (98.0%)48 (96.0%)
Females1 (2.0%)2 (4.0%)
Age26.7±6.932.4±7.2
GenotypeWild-type1420
Heterozygotes2522
Homozygotes108

Genotypic characteristics of patients with and without hospitalization at the Bursa Treatment and Research Center for Alcohol and Drug Addiction, Bursa, Turkey_

Genotypic Characteristics Total (n)Total (n)
Wild-TypeHomozygotes
Hospitalizationyesn(%)33 (82.2)4 (10.8)37 (100.0)
non(%)6 (50.0)6 (50.0)12 (100.0)
Total (n)n(%)39 (79.6)10 (20.4%)49 (100.0)
Language: English
Page range: 63 - 68
Published on: Aug 26, 2020
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2020 Y Nennicioglu, H Kaya, S Eraybar, S Atmaca, O Gorukmez, E Armagan, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.