Figure 1
Methylation status of RANKL and FSHR genes in pre- and postmenopausal women_
| Genes | Postmenopause | Premenopause | Positive Hot Flashes History | Negative Hot Flashes History |
|---|---|---|---|---|
| RANKL (M) n | 16 (45.7%) | 10 (33.3%) | 12 (75.0%) | 4 (25.0%) |
| RANKL (U) n | 19 (54.3%) | 20 (66.7%) | 7 (36.8%) | 12 (63.2%) |
| FSHR(M) n | 18 (51.4%) | 20 (66.7%) | 13 (72.2%) | 5 (27.8%) |
| FSHR (U) n | 17 (48.6%) | 10 (33.3%) | 6 (35.3%) | 11 (64.7%) |
Methylation status of RANKL and FSHR genes and postmenopausal women who have hot flashes_
| Genes | Positive Hot Flashes History | Negative Hot Flashes History | p Value |
|---|---|---|---|
| RANKL (M) n | 12 (75.0%) | 4 (25.0%) | 0.024 |
| RANKL (U) n | 7 (36.8%) | 12 (63.2%) | |
| FSHR(M) n | 13 (72.2%) | 5 (27.8%) | 0.028 |
| FSHR (U) n | 6 (35.3%) | 11 (64.7%) |