Figure 1
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Figure 4
The median values (mmol/L) and interquartile range (IQR) of the lipid profile parameters in both time points_
| Median Concentration in T1 (mmol/L) (IQR) | Median Concentration in T2 (mmol/L) (IQR) | p Value (Wilcoxon signed-rank test) | |
|---|---|---|---|
| Total cholesterol | 4.26 (Q1=3.89; Q3=4.73) | 4.11 (Q1=3.82; Q3=4.63) | 0.695 |
| High-density lipoprotein | 1.30 (Q1=1.16; Q3=1.54) | 1.27 (Q1=1.20; Q3=1.41) | 0.658 |
| Low-density lipoprotein | 2.39 (Q1=1.97; Q3=2.85) | 2.27 (Q1=2.04; Q3=2.74) | 0.778 |
| Triglycerides | 0.85 (Q1=0.60; Q3=1.36) | 1.09 (Q1=0.70; Q3=1.46) | 0.235 |
The results of statistical analysis regarding correlations between PPARD gene expression level (median RQ value) and the other studied parameters (Spearman’s rank correlation coefficient)_
| PPARD Gene Expression | ||
|---|---|---|
| RQ Value in T1 | RQ Value in T2 | |
| Total cholesterol (mmol/L) | rho = 0.24; p = 0.289 | rho = 0.43; p = 0.070 |
| High-density lipoprotein (mmol/L) | rho = 0.25; p = 0.257 | rho = 0.45; p = 0.052 |
| Low-density lipoprotein (mmol/L) | rho = –0.35; p = 0.111 | rho = –0.21; p = 0.401 |
| Triglycerides (mmol/L) | rho = 0.12; p = 0.600 | rho = 0.18; p = 0.470 |
| Absolute fat tissue (kg) | rho = 0.24; p = 0.285 | rho = –0.46; p = 0.031 |
| Relative fat tissue (%) | rho = 0.18; p = 0.418 | rho = –0.32; p = 0.147 |