Catalytic Effect of Mo-Al2O3-PTSA on the Synthesis of 4,5-Dihydro-3-(naphthalen-6-yl)-1-phenyl-5-(thiophen-2-yl)-1H-pyrazoline

Subramanian Balasundari; Pandiyan Sudha; Paneerselvam Gayathri; Kalyanasundaram Devika; Inbasekaran Muthuvel; Ganesamoorthy Thirunarayanan

doi:10.2478/auoc-2026-0007

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Catalytic Effect of Mo-Al2O3-PTSA on the Synthesis of 4,5-Dihydro-3-(naphthalen-6-yl)-1-phenyl-5-(thiophen-2-yl)-1H-pyrazoline

Ovidius University Annals of Chemistry

Volume 37 (2026): Issue 1 (January 2026)

By: Subramanian Balasundari, Pandiyan Sudha, Paneerselvam Gayathri, Kalyanasundaram Devika, Inbasekaran Muthuvel and Ganesamoorthy Thirunarayanan

Open Access

|Jun 2026

Abstract

The heterogeneous Mo-Al₂O₃-PTSA catalyst was used for the synthesis of 4,5-dihydro-3-(naphthalen-6-yl)-1-phenyl-5-(thiophen-2-yl)-1H-pyrazoline by one-pot three-component condensation cum cyclization process of 2-acetylnaphthalene, thiophene-2-carbaldehyde and phenyl hydrazine hydrochloride under conventional method. This condensation-cyclization reaction exhibits good yield of product and the solid catalyst was recycled. The newly synthesized 1H-pyrazoline was confirmed by physico-chemical parameters, analytical, and spectral (FT-IR, ¹H,¹³C NMR& mass) analysis. Also, in this synthetic approach, the effect of catalysts and solvents on the reaction yield was examined.

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Articles in this issue

DOI: https://doi.org/10.2478/auoc-2026-0007 | Journal eISSN: 2286-038X | Journal ISSN: 1583-2430

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Language: English

Page range: 61 - 66

Submitted on: Jan 25, 2026

Accepted on: May 30, 2026

Published on: Jun 23, 2026

Published by: Ovidius University of Constanta

In partnership with: Paradigm Publishing Services

Keywords:

Mo-Al₂O₃-PTSA,

1H-pyrazoline,

One-pot three component synthesis,

Related subjects:

© 2026 Subramanian Balasundari, Pandiyan Sudha, Paneerselvam Gayathri, Kalyanasundaram Devika, Inbasekaran Muthuvel, Ganesamoorthy Thirunarayanan, published by Ovidius University of Constanta
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 37 (2026): Issue 1 (January 2026)