Ultrasound assisted synthesis and pharmacological evaluation of some (E)-1,2,3-triphenylprop-2-en-1-ones

Veerendiran Mala; Inbasekaran Muthuvel; Ganesamoorthy Thirunarayanan; Saravanan Palavanivel Sakthinathan; Ranganathan Arulkumaran; Venkatesan Mani; Rajasekaran Sundararajan; Dakshnamoorthy Kamalakkannan; Ramamurthy Suresh; Veeramalai Usha

doi:10.2478/auoc-2020-0024

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Ultrasound assisted synthesis and pharmacological evaluation of some (E)-1,2,3-triphenylprop-2-en-1-ones

Ovidius University Annals of Chemistry

Volume 31 (2020): Issue 2 (July 2020)

By: Veerendiran Mala, Inbasekaran Muthuvel, Ganesamoorthy Thirunarayanan, Saravanan Palavanivel Sakthinathan, Ranganathan Arulkumaran, Venkatesan Mani, Rajasekaran Sundararajan, Dakshnamoorthy Kamalakkannan, Ramamurthy Suresh and Veeramalai Usha

Open Access

|Dec 2020

Abstract

More than 85% yield of (E)-1,2,3-triphenylprop-2-en-1-ones were synthesized using disodium hydrogen phosphate (Na₂HPO₄) catalyzed ultrasound assisted aldol condensation of 1,2-diphenylethanone and various substituted benzaldehydes. Synthesized (E)-1,2,3-triphenylprop-2-en-1-ones were examined by their spectroscopic data, yield, micro analysis and physical constants. The effect of solvent on the yield was investigated. The pharmacological effects such as antibacterial and antifungal activities of synthesized enones were evaluated with Bauer-Kirby disc diffusion method.

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Articles in this issue

DOI: https://doi.org/10.2478/auoc-2020-0024 | Journal eISSN: 2286-038X | Journal ISSN: 1583-2430

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Language: English

Page range: 152 - 157

Submitted on: Jul 8, 2020

Accepted on: Nov 21, 2020

Published on: Dec 21, 2020

Published by: Ovidius University of Constanta

In partnership with: Paradigm Publishing Services

Publication frequency: 2 issues per year

Keywords:

triphenyl enones,

ultrasonication,

disodium hydrogen phosphate,

aldol condensation,

solvent effect,

antimicrobial activity

Related subjects:

Chemistry,

Chemistry, other

© 2020 Veerendiran Mala, Inbasekaran Muthuvel, Ganesamoorthy Thirunarayanan, Saravanan Palavanivel Sakthinathan, Ranganathan Arulkumaran, Venkatesan Mani, Rajasekaran Sundararajan, Dakshnamoorthy Kamalakkannan, Ramamurthy Suresh, Veeramalai Usha, published by Ovidius University of Constanta
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 31 (2020): Issue 2 (July 2020)