![Analgesic activity of newly synthesized 7-chloro–2–methyl-4H–benzo[d] [1,3]–oxazin–4–one and 3–amino-7-chloro-2–methyl-quinazolin-4(3H)–one Cover](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/6470c2b271e4585e08aa4c70/cover-image.jpg)
References
- [1]. D. Wang and F. Gao, Quinazoline derivatives: synthesis and bioactivities, Chemistry Central Journal 7 (2013) 95. Doi: 10.1186/1752-153X-7-95 10.1186/1752-153X-7-95
- [2]. V. Chandregowda, A.K. Kush, G. Chandrasekara Reddy, Synthesis and in vitro antitumor activities of novel 4-anilinoquinazoline derivatives, European Journal of Medicinal Chemistry 44 (2009) 3046 - 3055. Doi: 10.1016/j.ejmech.2008.07.023. 10.1016/j.ejmech.2008.07.023
- [3]. V. Alagarsamy, V.R. Solomon, K. Dhanahal, Synthesis and pharmacological evaluation of some 3-phenyl-2-substituted-3H-quinazolin-4-one as analgesic, anti-inflammatory agents, Bioorganic and Medicinal Chemistry 15 (2007) 235-241. Doi: 10.1016/j.bmc.2006.09.065 10.1016/j.bmc.2006.09.065
- [4]. K. Baba, K. Takeuchi, F. Hamaski, M. Kozawa, Chemical Studies on the Constituents of the Thymelaeaceous Plants. I.: Structures of Two New Flavans from Daphne odora THUNB, Chemical and Pharmaceutical Bulletin 34 (1986) 595-598.
- [5]. R. Rohini, P. Muralidhar Reddy, K. Shanker, A. Hu, V. Ravinder, Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines, European Journal of Medicinal Chemistry 45 (2010) 1200 - 1205. Doi: 10.1016/j.ejmech.2009.11.038 10.1016/j.ejmech.2009.11.038
- [6]. L. Antipenko, A. Karpenko, S. Kovalenko, A. Katsev, E. Komarovska - Porokhnyavets, V. Novikov, A. Chekotilo, Synthesis of new 2-thio-[1,2,4]triazolo[1,5-c]quinazoline derivatives and its antimicrobial activity, Chemical and Pharmaceutical Bulletin 57 (2009) 580-585. Doi: 10.1248/cpb.57.580 10.1248/cpb.57.580
- [7]. V. Jatav, S. Kashau, P. Mishra, Synthesis and antimicrobial activity of some new 3-[5-(4-substituted) phenyl-1,3,4-oxadiazole-2yl]-2-styrylquinazoline-4(3H)-ones, Medicinal Chemistry Research 17 (2008) 205 - 211. Doi: 10.1007/s00044-007-9054-3 10.1007/s00044-007-9054-3
- [8]. A.A. Aly, Synthesis of novel quinazoline derivatives as antimicrobial agents, Chinese Journal of Chemistry 21 (2003) 339 - 346. Doi: 10.1002/cjoc.20030210324
- [9]. P.N. Chandrika, T. Yakaiah, B. Narsalah, V. Sridhar, G. Venugopal, J.V. Rao, K.P. Kumar, U.S.N. Murthy, A.R.R. Rao, Synthesis leading to novel 2,4,6-trisubstituted quinazoline derivatives, their antibacterial and cytotoxic activity against THP-1, HL-60 and A375 cell lines, Indian Journal of Chemistry 48B (2009) 840- 47.
- [10]. P. Paneersalvam, T. Raj, M.P.S. Ishar, B. Singh, V. Sharma, B.A. Rather, Anticonvulsant activity of Schiff bases of 3-amino - 6, 8 -dibromo - 2 - phenyl - quinazolin - 4(3H) - ones, Indian Journal of Pharmaceutical Sciences 72 (2010) 375 - 378. Doi: 10.4103/0250-474X.70488 70488
- [11]. P. Nandy, M.T. Vishalakshi, A.R. Bhat, Synthesis and antitubercular activity of Mannich bases of 2-methyl-3H-quinazolin-4-ones, Indian Journal of Heterocyclic Chemistry 15 (2006) 293 - 294.
- [12]. G. Saravanan, V. Alagarsamy, C.R. Prakash, Synthesis and evaluation of antioxidant activities and evaluation of antioxidant activities of novel quinazoline derivatives, International Journal of Pharmacy and Pharmaceutical Sciences 2 (2010) 83 - 86.
- [13]. S. Sasmal, G. Balaji, H.R. Kanna Reddy, D. Balasubrahmanyam, G. Srinvas, S.K. Kyasa, P.K. Sasmal, I. Khanna, R. Talwar, J. Suresh, V.P. Jadhav, S. Muzeebs, D. Slashikumar, K. Harinder Reddy, V.I. Sebastian, T.M. Frimurer, O. Rist, L. Elster, T. Hogberg, Design and optimization of quinazolin derivatives as elanin concentration hormone receptor I (MCHRI) antagonists. Bioorganic and Medicinal Chemistry Letters 23 (2012) 3157 - 3162. Doi: 10.1016/j.bmcl.2012.03.050 10.1016/j.bmcl.2012.03.050
- [14]. M. Alvarado, M. Barcelo, L. Carro, C.F. Masaguer, E. Ravina, Synthesis and biological evaluation of new quinazoline and cinnoline derivatives as potential atypical antipsychotics, Chemistry and Biodiversity 3 (2006) 106 - 117. Doi: 10.1002/cbdv.200690001 10.1002/cbdv.200690001
- [15]. M. Bhalla, V.K. Srivastava, T.N. Bhalla, K. Shanker, Anti-inflammatory and analgesic activity of indolylquinazolones and their congeners, Arzneimittelforschung 43 (1993) 595 - 600.
- [16]. A. Hitkari, M. Saxena, A.K. Verma, M. Gupta, M.P. Shankar, Substituted quinazolines and their anti-inflammatory activity, Bull. Chem. Farm. 134 (1995) 609 - 615.
- [17]. V. Alagarsamy, V.R. Solomon, G. Vanikavisha, V. Saluchamy, M. Pavichandran, A.A. Sujin, A Thangthirupathy, S. Amuthalakshmi, R. Revathi, Synthesis, analgesic, anti-inflammatory and antibacterial activities of some novel 2- phenyl -3 - substituted quinazolin - 4 (3H) - ones, Biological and Pharmaceutical Bulletin 5 (2002) 1432 - 1435.
- [18]. V. Alagarsamy, V. Muthukumar, N. Pavalarani, P. Vasanthanathan, R. Pevathi, Synthesis, analgesic, anti-inflammatory and antibacterial activities of some novel 2-methyl-3-substituted quinazolin-4-(3H)-ones, Biological and Pharmaceutical Bulletin 26 (2003) 557 - 559.
- [19]. V. Alagarsamy, R. Rajesh, R. Meena, S. Vijaykumar, K.V. Ramseshu, T.D. Anandakumar, Synthesis, analgesic and anti-inflammatory and antibacterial activities of some novel 2-methylthio - 3 - substituted quinazolin - 4 (3H)-ones, Biological and Pharmaceutical Bulletin 27 (2004) 652 - 656.
- [20]. P.O. Osarumwense, O. Iyekowa, Synthesis and antibacterial activity of 7-chloro-2-methyl-4H-benzo[d] [1,3] - oxazin-4-one and 3-amino-7-chloro-2-methyl-quinazolin-4(3H)-one, Tropical Journal of Natural Product Research 1 (2017) 173-175. Doi: 10.26538/tjnpr/v1i4.7
- [21]. R.M. Gene, L. Segura, T. Adzet, E. Marin, J. Inglesias, Heterothecainuloides: Anti-inflammatory and analgesic effect, Journal of Ethnopharmacology 60 (1998) 157-162. Doi: 10.1016/S0378-8741(97)00155-4 10.1016/S0378-8741(97)00155-4
- [22]. R. Koster, M. Anderson, E.J. De Beer, Acetic acid for analgesic screening, Fed. Proc. 18 (1959) 412.
- [23]. H.O.J. Collier, L.G. Dinneen, C.A. Johnson, C. Schneider, The abdominal constriction response and its suppression by analgesic drugs in the mouse, British Journal of Pharmacology 32 (1968) 295-310.
- [24]. G.A. Bentley, S.H. Newton, J. Starr, Evidence for action of morphine and enkephalins on sensory nerve ending in the mouse peritoneum, British Journal of Pharmacology 73 (1981) 325-332.
- [25]. K.W. Bentley, The isoquinolinalkaliods, in Comprehensive Medicinal Chemistry, Pergamon Press, London (1983).
- [26]. R. Derardt, S. Jongney, F. Delvalcee, M. Falhout, Release of prostaglandins E and F in an algogenic reaction and its inhibition, European Journal of Pharmacology 51 (1980) 17-24.
- [27]. J.D. Levini, W. Lau, G. Kwait, E.J. Goetal, Leukotriene B4 produces hyperanalgesia that is dependent on the polymorphonuclear leucocytes, Science 225 (1984) 743-745.
- [28]. A.K. Dhara, V. Suba, T. Sen, S. Pal, A.K. Nag Chaudhuiri, Preliminary studies on the anti-inflammatory and analgesic activity of methanolic fraction of the root of Tragia involucrate Linn, Journal of Ethnopharmacology 72 (2000) 265-268. Doi: 10.1016/S0378-8741(00)00166-510.1016/S0378-8741(00)00166-5