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Haematological and Genotoxicity Evaluations of Phytochemical Compounds from n-Hexane Extract of Uvaria chamae Stem on Selected Organs in Mice Cover

Haematological and Genotoxicity Evaluations of Phytochemical Compounds from n-Hexane Extract of Uvaria chamae Stem on Selected Organs in Mice

Open Access
|Aug 2018

References

  1. Adelodun, V.O., Elusiyan, C.A., Olorunmola, F.O., Adewoyin, F.B., Omisore, N.O., Adepiti, A.O., Agbedahunsi, J.M. and Adewunmi, C.O., 2013. Evaluation of antitrypanosomal and anti-inflammatory activities of selected Nigerian medicinal plants in mice. Afr. J. Tradit. Complement. Altern. Med. 10(6), 469-47610.4314/ajtcam.v10i6.13
  2. Auffray, B., 2007. Protection against singlet oxygen, the main actor of sebum squalene peroxidation during sun exposure, using Commiphora myrrha essential oil. Int. J. Cosmet. Sci. 29, 23-2910.1111/j.1467-2494.2007.00360.x
  3. Ayedoun, M.A., Moudachirou, M., Adeoti, B.S., Menut, C., Lamaty, G. and Bessiére, J., 1997. Aromatic Plants of Tropical West Africa. VII. Essential Oil of Leaf and Root Bark of Uvaria chamae P. Beauv. from Benin. J. Essential Oil Res., 11(1), 23-2610.1080/10412905.1999.9701060
  4. Bouic, P.J., Clark, A., Lamprecht, J., Freestone, M., Pool, E.J., Liebenberg, R.W., et al., 1999. The effects of β-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners: inhibition of post marathon immune suppression and inflammation. Int. J. Sports Med. 20(4), 258-26210.1055/s-2007-971127
  5. Brühne, F. and Wright, E., 2007. Benzyl Alcohol, Ullmann’s Encyclopedia of Industrial Chemistry (7), 7
  6. Burns, D.A., 2010, Diseases Caused by Arthropods and Other Noxious Animals, in Tony Burns; et al., Rook’s Textbook of Dermatology, 2 (8), 38-4110.1002/9781444317633.ch38
  7. Charles, D.H., William, L.L., Ken, H. and Jon, C., 1979. Uvarinol: a novel cytotoxic tribenzylated flavanone from Uvaria chamae. J. Org. Chem., 44(25), 4709–471010.1021/jo00393a054
  8. Farnsworth, N.R., Akerele, O.O., Bingel, A.S., Soejarta, D.D. and Eno, Z., 1985. Medicinal plants in therapy. Bull. World Health Org., 63, 965–981
  9. Feki, A., Saad, B.H., Jaballi, I., Magne, C., Boudawara, O., Zeghal, K.M., Hakim, A., Ali, B.Y. and Amara, B.I., 2015. Methyl thiophanateinduced toxicity in liver and kidney of adult rats: a biochemical, molecular and histopathological approach. Cell Mol. Biol. (Noisy le Grand), 63(2), 20-2810.14715/cmb/2017.63.2.4
  10. Gallo, M.B.C., and Sarachine, M.J., 2009. Biological activities of Lupeol. Int. J. Biomed. Pharm. Sci., 3(1), 46–66
  11. Geetha, T., and Varalakshmi, P., 2001. Anti-inflammatory activity of lupeol and lupeol linoleate in rats. J. Ethnopharm., 76(1), 77–8010.1016/S0378-8741(01)00175-1
  12. Gibb, R.K., Taylor, D.D., Wan, T., O’Connor, D.M., Doering, D.L., and
  13. Gerçel-Taylor, C., 1997. Apoptosis as a measure of chemosensitivity to cisplatin and taxol therapy in ovarian cancer cell lines. Gynecol Oncol. 65(1), 13-2210.1006/gyno.1997.46379103385
  14. Kaur, N., Chaudhary, J., Jain, A. and Kishore, L., 2011. Stigmasterol: A Comprehensive Review. Int. J. Pharm. Sci. Res., 2(9), 2259-2265
  15. Kim, T.H., Lim, H.J., Kim, M.S. and Lee, M.S., 2012. Dietary supplements for benign prostatic hyperplasia: An overview of systematic reviews. Maturitas, 73(3), 180–18510.1016/j.maturitas.2012.07.00722883375
  16. Kone, M., Toure, A., Ouattara, K. and Coulibaly, A., 2015. Phytochemical Composition, Antioxidant and Antibacterial Activities of Root of Uvaria chamae P. Beauv. (Annonaceae) used in Treatment of Dysentery in North of Côte d’Ivoire. Int. J. Pharmacog. Phytochem. Res., 7(6), 1047-1053
  17. Moses, O.S., Olowu, R.A., Noura S.D. and William, N.S., 2013. 1-Nitro- 2-phenylethane dominates the chemical composition of the leaf essential oil of Uvaria chamae from Badagry, Nigeria. Am. J. Essential Oils Nat. Prod., 1(1), 48-50
  18. OECD, 2008. Guidelines for the Testing of Chemicals; Test No. 425: Acute Oral Toxicity - Up-and-Down-Procedure (UDP).
  19. Oguntimein, B.O., Ekundayo, O.O., Laakso, I. and Hiltunen, R., 1989. Volatile Constituents of Uvaria chamae Leaves and Root Bark. Planta Medica. 55(3), 312-31310.1055/s-2006-96201617262427
  20. Okwu, D. and Iroabuchi, F., 2009. Phytochemical Composition and Biological Activities of Uvaria chamae and Clerodendoron splendens. E-Journal Chem., 6(2), 553-56010.1155/2009/190346
  21. Okwuosa, O.M., Chukwura, E.I., Chukwuma, G.O., Okwuosa, C.N., Enweani, I.B., Agbakoba, N.R., Chukwuma, C.M., Manafa, P.O., and Umedum, C.U., 2012. Phytochemical and antifungal activities of Uvaria. chamae leaves and roots, Spondias mombin leaves and bark and Combretum racemosum leaves. Afr. J. Med. Sci., 41, 99-103
  22. Oluremi, B.B., Osungunna, M.O., and Omafuma, O.O., 2010. Comparative assessment of antibacterial activity of Uvaria chamae parts. Afr. J. Microbiol. Res. 4(13), 1391-1394
  23. Rudkowska, I., AbuMweis, S.S., Nicolle, C., and Jones, P.J., 2008. Cholesterol-lowering efficacy of plant sterols in low-fat yogurt consumed as a snack or with a meal. J. Am. Coll. Nutr., 27(5), 588–59510.1080/07315724.2008.1071974218845709
  24. Sarkar, D., Sharma, A. and Talukder, G., 2008. Plant extracts as modulators of genotoxic effects. The Botan. Rev., 62(4), 275-300.10.1007/BF02856614
  25. Shaikh, J., 2005. Benzyl Benzoate, in Philip Wexler, Encyclopedia of Toxicology, Elsevier (1), 264–26510.1016/B0-12-369400-0/00122-8
  26. Thierry, A.C., Joachim, D.G., Kpoviessi, S.D.S., Accrombessi, G.C., Moudachirou, M. and Gbeassor, M., 2012.Antihemolytic Properties of Extracts of Six Plants Used in the Traditional Treatment of Sickle Cell Disease in Benin. J. Appl. Pharm. Sci., 2(3), 8-13
  27. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianch, A.,Chiavarini, M., and Impecciatore, M., 2006. Comparative screening of plant essential oils: Phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci., 78, 1419-143210.1016/j.lfs.2005.07.02016274702
  28. Uhl M, Plewa M.J, Majer B.J, Knasmüller S., 2003. Basic principles of genetic toxicology with an emphasis on plant bioassays In: Maluszynska J, Plewa M, editors. Bioassays in Plant Cells for Improvement of Ecosystem and Human Health. Katowice: Wydawnictvo Uniwersytetu Ślaskiego, pp. 11-30
  29. Uwaifo, A.O. and Bababunmi, E.A., 1984. Liver carcinogenesis in tropical Africa. IARC Sci Publ. 63, 59-88
  30. Wilt, T., Ishani, A., MacDonald, R., Stark, G., Mulrow, C. and Lau, J., 2000. Beta-sitosterols for benign prostatic hyperplasia. The Cochrane Libr. 2, CD00104310.1002/14651858.CD002289
Language: English
Page range: 28 - 34
Submitted on: Apr 13, 2018
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Accepted on: Jun 6, 2018
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Published on: Aug 29, 2018
Published by: Sciendo
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2018 Oladipupo R. Akolade, Alaribe S. Chinwe, Balogun T. Olalekan, Akere T. Halima, Ayanda A. Fatima, Toye T. Emuejevoke, Coke A.B. Herbert, published by Sciendo
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