Abstract
A discrepancy between the production of reactive oxygen species [ROS] and the body’s capacity to cleanse or repair the resulting damage is known as oxidative stress. Antioxidants shield cells against ROS and free radicals, which are extremely reactive because of their unpaired electrons, by preventing other molecules from oxidizing. Antioxidants from the Zingiberaceae family, which is well-known for its culinary and therapeutic applications, scavenge free radicals, chelate metal ions, alter enzyme function, and control gene expression. The antioxidant capacity of Zingiberaceae plant extracts and compounds is assessed using in vitro tests such as DPPH, FRAP, and ABTS. Animal research conducted in vivo clarifies these plants’ bioavailability, metabolism, and impacts on diseases linked to oxidative stress. Lipid peroxidation, protein oxidation, DNA damage, and endogenous antioxidant defenses are examples of biomarkers of oxidative stress that shed light on the mechanisms behind Zingiberaceae antioxidant treatments and highlight their potential as a treatment for oxidative stress.