[1]. Kemzuraite, A.; Venskutonis, P.R.; Baranauskiene, R.; Navikiene, D., Optimization of supercritical CO2 extraction of different anatomical parts of lovage (Levisticum officinale Koch.) using response surface methodology and evaluation of extracts composition, Journal of Supercritical Fluids, 2014, 87, 93-103.
[2]. Khodashenas, M.; Keramat, B.; Emamipoor, Y., Germination response of endangered medicinal plant, Levisticum officinale, to stratification and some plant growth regulators, Journal of Biodiversity and Environmental Science, 2015, 7(3), 228-235.
[4] El-Din, A.A.E.; Hendawy, S.F., Comparative efficiency of organic and chemical fertilizers on herb production and essential oil of lovage plants grown in Egypt, American-Eurasian Journal of Agricultural and Environmental Sciences, 2010, 8, 60-66.
[6]. Dobrinas, S.; Stanciu, G.; Lupsor, S., Total phenolic content and HPLC characterization of some culinary herbs, Journal of Science and Arts, 2017, 2, 321-330.
[8]. Justesen, U.; Knuthsen, P., Composition of flavonoids in fresh herbs and calculation of flavonoid intake by use of herbs in traditional Danish dishes, Food Chemistry, 2001, 73(2), 245-250.
[12]. Papuc, C.; Predescu, N.C.; Goran, G.; Petrescu, C., Total phenolic content and antioxidant activity of some aromatic herbs used in traditional Romanian cuisine, Annals of the Academy of Romanian Scientists Series on Agriculture, Silviculture and Veterinary Medicine Sciences, 2020, 9(1), 17-24.
[14]. Tajner-Czopek, A.; Gertchen, M.; Rytel, E.; Kita, A.; Kucharska, A.Z.; Sokol-Letowska, A., Study of antioxidant activity of some medicinal plants having high content of caffeic acid derivatives, Antioxidants, 2020, 9(5), 412.
[15]. Mohamadi, N.; Rajaei, P.; Moradalizadeh, M.; Amiri, M.S., Essential oil composition and antioxidant activity of Levisticum officinale Koch. at various phenological stages, Journal of Medicinal Plants, 2017, 16(61), 45-55.
[18]. Castañeda-Ovando, A.; de Lourdes Pacheco-Hernández, M.; Páez-Hernández, E.; Rodríguez, J.A.; Galán-Vidal, C.A., Chemical studies of anthocyanins: A review, Food Chemistry, 2009, 113(4), 859-871.
[20]. Ferk, F.; Chakraborty, A.; Jäger, W.; Kundi, M.; Bichler, J.; Mišík, M.; Wagner, K.H.; Grasl-Kraupp, B.; Sagmeister, S.; Haidinger, G.; Hoelzl, C.; Nersesyan, A.; Dušinská, M.; Simić, T.; Knasmüller, S., Potent protection of gallic acid against DNA oxidation: Results of human and animal experiments, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2011, 715(1-2), 61-71.
[25]. Jabbari, S.; Bananej, M.; Zarei, M.; Komaki, A.; Hajikhani, R., Effects of intrathecal and intracerebroventricular microinjection of kaempferol on pain: possible mechanisms of action, Research in Pharmaceutical Sciences, 2021, 16(2), 203-216.
[26]. Selloum, L.; Bouriche, H.; Tigrine, C.; Boudoukh, C., Anti-inflammatory effect of rutin on rat paw oedema, and on neutrophils chemotaxis and degranulation, Experimental and Toxicologic Pathology, 2003, 54(4), 313-318.
[28]. Fallah, A.A.; Sarmast, E.; Fatehi, P.; Jafari, T., Impact of dietary anthocyanins on systemic and vascular inflammation: Systematic review and meta-analysis on randomised clinical trials. Food and Chemical Toxicology, 2020, 135, 110922.
[29]. Naveed, M.; Hejazi, V.; Abbas, M.; Kamboh, A.A.; Khan, G.J.; Shumzaid, M.; Ahmad, F.; Babazadeh, D.; Fang Fang, X.; Modarresi-Ghazani, F.; WenHua, L.; XiaoHui, Z., Chlorogenic acid (CGA): A pharmacological review and call for further research, Biomedicine and Pharmacotherapy, 2018, 97, 67-74.
[30]. Nile, S.H.; Ko, E.Y.; Kim, D.H.; Keum, Y.S., Screening of ferulic acid related compounds as inhibitors of xanthine oxidase and cyclooxygenase-2 with anti-inflammatory activity, Revista Brasileira de Farmacognosia, 2016, 26, 50-55.
[31]. Rahimi, V.B.; Ghadiri, M.; Ramezani, M.; Askari, V.R., Antiinflammatory and anti-cancer activities of pomegranate and its constituent, ellagic acid: Evidence from cellular, animal, and clinical studies, Phytotherapy Research, 2020, 34(4), 685-720.
[35]. Mansouri, M.T.; Naghizadeh, B.; Ghorbanzadeh, B.; Farbood, Y., Central and peripheral antinociceptive effects of ellagic acid in different animal models of pain, European Journal of Pharmacology, 2013, 707(1-3), 46-53.
[36]. Sargazi, M.L.; Saravani, R.; Shahraki, A., Hydroalcoholic extract of Levisticum officinale increases cGMP signaling pathway by down-regulating PDE5 expression and induction of apoptosis in MCF-7 and MDA-MB-468 breast cancer cell lines, Iranian Biomedical Journal, 2019, 23(4), 280-286.
[39]. Bogucka-Kocka, A.; Smolarz, H.D.; Kocki, J., Apoptotic activities of ethanol extracts from some Apiaceae on human leukaemia cell lines, Fitoterapia, 2008, 79(7-8), 487-497.
[40]. Sertel, S.; Eichhorn, T.; Plinkert, P.K.; Efferth, T., Chemical composition and antiproliferative activity of essential oil from the leaves of a medicinal herb, Levisticum officinale, against UMSCC1 head and neck squamous carcinoma cells, Anticancer Research, 2011, 31(1), 185-191.
[45]. Li, D.; Wang, P.; Luo, Y.; Zhao, M.; Chen, F., Health benefits of anthocyanins and molecular mechanisms: Update from recent decade, Critical Reviews in Food Science and Nutrition, 2017, 57(8), 1729-1741.
[49]. Gholamhoseinian, A.; Moradi, M.N.; Sharifi-far, F., Screening the methanol extracts of some Iranian plants for acetylcholinesterase inhibitory activity, Research in Pharmaceutical Sciences, 2009, 4(2), 105-112.
[51]. Raafat, K., Identification of phytochemicals from North African plants for treating Alzheimer’s diseases and of their molecular targets by in silico network pharmacology approach, Journal of Traditional and Complementary Medicine, 2021, 11(3), 268-278.
[53]. Bhutada, P.; Mundhada, Y.; Bansod, K.; Ubgade, A.; Quazi, M.; Umathe, S.; Mundhada, D., Reversal by quercetin of corticotrophin releasing factor induced anxiety- and depression-like effect in mice, Progress in Neuro-Psychopharmacology and Biologycal Psychiatry, 2010, 34, 955-960.
[56]. dos Santos, J.S.; Cirino, J.P.G.; Carvalho, P.O.; Ortega, M.M., The pharmacological action of kaempferol in central nervous system diseases: A review, Frontiers in Pharmacology, 2021, 11, 565700.
[59]. Bouayed, J.; Rammal, H.; Dicko, A.; Younos, C.; Soulimani, R., Chlorogenic acid, a polyphenol from Prunus domestica (Mirabelle), with coupled anxiolytic and antioxidant effects, Journal of the Neurological Sciences, 2007, 262(1-2), 77-84.
[61]. Thapliyal, S.; Singh, T.; Handu, S.; Bisht, M.; Kumari, P.; Arya, P.; Srivastava, P.; Gandham, R., A review on potential footprints of ferulic acid for treatment of neurological disorders, Neurochemical Research, 2021, 46, 1043-1057.
[62]. Shabani, S.; Rabiei, Z.; Amini-Khoei, H., Exploring the multifaceted neuroprotective actions of gallic acid: a review, International Journal of Food Properties, 2020, 23(1), 736-752.
[63]. Alfei, S.; Turrini, F.; Catena, S.; Zunin, P.; Grilli, M.; Pittaluga, A.M.; Boggia, R., Ellagic acid a multi-target bioactive compound for drug discovery in CNS? A narrative review, European Journal of Medicinal Chemistry, 2019, 183, 111724.
[69]. Ghaedi, N.; Pouraboli, I.; Askari, N., Antidiabetic properties of hydroalcoholic leaf and stem extract of Levisticum officinale: an implication for α-amylase inhibitory activity of extract ingredients through molecular docking, Iranian Journal of Pharmaceutical Research, 2020, 19(1), 231-250.
[70]. Gholamhoseinian, A.; Fallah, H.; Sharifi-far, F.; Mirtajaddini, M., The inhibitory effect of some Iranian plant extracts on the alpha glucosidase, Iranian Journal of Basic Medical Sciences, 2008, 11(1), 1-9.
[71]. Gholamhoseinian, A.; Shahouzehi, B.; Sharifi-far, F., Inhibitory effect of some plant extracts on pancreatic lipase, International Journal of Pharmacology, 2010, 6(1), 18-24.
[74]. Nabavi, S.F.; Russo, G.L.; Daglia, M.; Nabavi, S.M., Role of quercetin as an alternative for obesity treatment: You are what you eat! Food Chemistry, 2015, 179, 305-310.
[76]. Shi, G.J.; Li, Y.; Cao, Q.H.; Wu, H.X.; Tang, X.Y.; Gao, X.H.; Yu, J.Q.; Chen, Z.; Yang, Y., In vitro and in vivo evidence that quercetin protects against diabetes and its complications: A systematic review of the literature, Biomedicine and Pharmacotherapy, 2019, 109, 1085-1099.
[77]. Zang, Y.; Zhang, L.; Igarashi, K.; Yu, C., The anti-obesity and anti-diabetic effects of kaempferol glycosides from unripe soybean leaves in high-fat-diet mice, Food and Function, 2015, 6(3), 834-841.
[82]. Ahangarpour, A.; Sayahi, M.; Sayahi, M., The antidiabetic and antioxidant properties of some phenolic phytochemicals: A review study, Diabetes and Metabolic Syndrome, 2019, 13(1), 854-857.
[83]. Singh, A.K.; Rana, H.K.; Singh, V.; Yadav, T.C.; Varadwaj, P.; Pandey, A.K., Evaluation of antidiabetic activity of dietary phenolic compound chlorogenic acid in streptozotocin induced diabetic rats: molecular docking, molecular dynamics, in silico toxicity, in vitro and in vivo studies, Computers in Biology and Medicine, 2021, 104462.
[84]. Narasimhan, A.; Chinnaiyan, M.; Karundevi, B., Ferulic acid exerts its antidiabetic effect by modulating insulin-signalling molecules in the liver of high-fat diet and fructose-induced type-2 diabetic adult male rat, Applied Physiology, Nutrition and Metabolism, 2015, 40(8), 769-781.
[87]. Seo, C.R.; Yi, B.R.; Oh, S.; Kwon, S.M.; Kim, S.; Song, N.J.; Cho, J.Y.; Park, K.M.; Ahn, J.Y.; Hong, J.W.; Kim, M.J.; Lee, J.H.; Park K.W., Aqueous extracts of hulled barley containing coumaric acid and ferulic acid inhibit adipogenesis in vitro and obesity in vivo, Journal of Functional Foods, 2015, 12, 208-218.
[90]. Kang, I.; Buckner, T.; Shay, N.F.; Gu, L.; Chung, S., Improvements in metabolic health with consumption of ellagic acid and subsequent conversion into urolithins: Evidence and mechanisms, Advances in Nutrition, 2016, 7(5), 961-972.
[94]. Ebrahimi, A.; Eshragh, A.; Mahzoonieh, M.R.; Lotfalian, S., Antibacterial and antibiotic-potentiation activities of Levisticum officinale L. extracts on pathogenic bacteria, International Journal of Infection, 2017, 4(2), e38768.
[98]. Escandón, R.A.; del Campo, M.; López-Solis, R.; Obreque-Slier, E.; Toledo, H., Antibacterial effect of kaempferol and (−)-epicatechin on Helicobacter pylori, European Food Research and Technology, 2016, 242, 1495-1502.
[100]. Jin, Y.S., Recent advances in natural antifungal flavonoids and their derivatives, Bioorganic and Medicinal Chemistry Letters, 2019, 29(19), 126589.
[101]. Patel, K.; Patel, D.K., Chapter 26 - The beneficial role of rutin, a naturally occurring flavonoid in health promotion and disease prevention: A systematic review and update, In: Watson RR, Preedy VR (editors), Bioactive food as dietary interventions for arthritis and related inflammatory diseases (2nd Ed), Academic Press, London, 2019, pp. 457-479.
[102]. Ragunathan, A.; Ravi, L., Potential antibacterial drug targets for quercetin and rutin: An in silico study using AutoDock, Der Pharmacia Lettre, 2015, 7(11), 68-72.
[104]. Rocha, M.F.G.; Sales, J.A.; da Rocha, M.G.; Galdino, L.M.; de Aguiar, L.; Pereira-Neto, W.A.; Cordeiro, R.A.; Castelo-Branco, D.S.C.M.; Sidrim, J.J.C.; Brilhante, R.S.N., Antifungal effects of the flavonoids kaempferol and quercetin: a possible alternative for the control of fungal biofilms, Biofouling, 2019, 35(3), 320-328.
[107]. Zhang, Z.; Pan, T., HPLC determination of chlorogenic acid in Verbena officinalis L. extract and its in-vitro antibacterial activity, Biomedical Research, 2017, 28(9), 3996-4001.
[108]. Ding, Y.; Cao, Z.; Cao, L.; Ding, G.; Wang, Z.; Xiao, W., Antiviral activity of chlorogenic acid against influenza A (H1N1/H3N2) virus and its inhibition of neuraminidase, Scientific Reports, 2017, 7, 45723.
[110]. Sung, W.S.; Lee, D.G., Antifungal action of chlorogenic acid against pathogenic fungi, mediated by membrane disruption, Pure and Applied Chemistry, 2010, 82(1), 219-226.
[111]. Borges, A.; Ferreira, C.; Saavedra, M.J.; Simões, M., Antibacterial activity and mode of action of ferulic and gallic acids against pathogenic bacteria, Microbial Drug Resistance, 2013, 19(4), 256-265.
[114]. De, R.; Sarkar, A.; Ghosh, P.; Ganguly, M.; Karmakar, B.C.; Saha, D.R.; Halder, A.; Chowdhury, A.; Mukhopadhyay, A.K., Antimicrobial activity of ellagic acid against Helicobacter pylori isolates from India and during infections in mice, Journal of Antimicrobial Chemotherapy; 2018, 73(6), 1595-1603.
[116]. Ani, V.; Varadaraj, M.C.; Naidu, K.A., Antioxidant and antibacterial activities of polyphenolic compounds from bitter cumin (Cuminum nigrum L.), European Food Research and Technology, 2006, 224, 109-115.
[119]. Miltonprabu, S.; Tomczyk, M.; Skalicka-Woźniak, K.; Rastrelli, L.; Daglia, M.; Nabavi, S.F.; Alavian, S.M.; Nabavi, S.M., Hepatoprotective effect of quercetin: From chemistry to medicine, Food and Chemical Toxicology, 2017, 108(Pt B), 365-374.
[120]. Wang, M.; Sun, J.; Jiang, Z.; Xie, W.; Zhang, Z., Hepatoprotective effect of kaempferol against alcoholic liver injury in mice, The American Journal of Chinese Medicine, 2015, 43(2), 241-254.
[122]. Danielewski, M.; Matuszewska, A.; Nowak, B.; Kucharska, A.Z.; Sozański, T., The effects of natural iridoids and anthocyanins on selected parameters of liver and cardiovascular system functions, Oxidative Medicine and Cellular Longevity, 2020, 2735790.
[130]. Girish, C.; Pradhan, S.C., Hepatoprotective activities of picroliv, curcumin, and ellagic acid compared to silymarin on carbon-tetrachloride-induced liver toxicity in mice, Journal of Pharmacology and Pharmacotherapeutics, 2012, 3(2), 149-155.
[132]. Tvrda, E.; Varga, A.; Slavik, M.; Arvay, J., Levisticum officinale and its effects on bovine spermatozoa activity, Journal of Microbiology, Biotechnology and Food Sciences, 2019, 8(5), 1212-1216.
[133]. Yuksel, Y.; Yuksel, R.; Yagmurca, M.; Haltas, H.; Erdamar, H.; Toktas, M.; Ozcan, O., Effects of quercetin on methotrexate-induced nephrotoxicity in rats, Human and Experimental Toxicology, 2017, 36(1), 51-61.
[140]. Ahmadvand, H.; Nouryazdan, N.; Nasri, M.; Adibhesami, G.; Babaeenezhad, E., Renoprotective effects of gallic acid against gentamicin nephrotoxicity through amelioration of oxidative stress in rats, Brazilian Archives of Biology and Technology, 2020, 63, e20200131.
[142]. Ibrahim, A.F.M.; Hafez, L.M.; Yousif, A.B., Protective role of polyphenols (anthocyanin, gallic acid) and blackberry juice against acrylamide reproductive toxicity in male rats, International Journal of Progressive Sciences and Technologies, 2020, 23(2), 292-300.
[145]. Izquierdo-Vega, J.A.; Madrigal-Santillán, E.O.; Chávez-Pagola, J.T.; Vega, M.C.V.; Sánchez-Gutiérrez, M., The activity of ellagic acid in male reproduction: A mini-review, International Journal of Medical Reviews, 2019, 6(4), 135-139.
[147]. Rolnik, A.; Żuchowski, J.; Stochmal, A.; Olas, B., Quercetin and kaempferol derivatives isolated from aerial parts of Lens culinaris Medik as modulators of blood platelet functions, Industrial Crops and Products, 2020, 152, 112536.
[152]. Oršolić, N.; Jeleč, Z.; Nemrava, J.; Balta, V.; Gregorovic, G.; Jelec, D., Effect of quercetin on bone mineral status and markers of bone turnover in retinoic acid-induced osteoporosis, Polish Journal of Food and Nutrition Sciences, 2018, 68(2), 149-162.
[153]. Wong, S.K.; Chin, K.Y.; Ima-Nirwana, S., The osteoprotective effects of kaempferol: The evidence from in vivo and in vitro studies, Drug Design, Development and Therapy, 2019, 13, 3497-3514. [154]. Sharma, A.R.; Nam, J.S., Kaempferol stimulates WNT/β-catenin signaling pathway to induce differentiation of osteoblasts, The Journal of Nutritional Biochemistry, 2019, 74, 108228.
[160]. Hou, T.; Zhang, L.; Yang, X., Ferulic acid, a natural polyphenol, protects against osteoporosis by activating SIRT1 and NF-κB in neonatal rats with glucocorticoid-induced osteoporosis, Biomedicine and Pharmacotherapy, 2019, 120, 109205.
[163]. Zhao, L.; Wang, H.; Du, X., The therapeutic use of quercetin in ophthalmology: recent applications, Biomedicine and Pharmacotherapy, 2021, 137, 111371.
[164]. Molitorisova, M.; Sutovska, M.; Kazimierova, I.; Barborikova, J.; Joskova, M.; Novakova, E.; Franova, S., The anti-asthmatic potential of flavonol kaempferol in an experimental model of allergic airway inflammation, European Journal of Pharmacology, 2021, 891, 173698.