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A Polarized Light Microscopy Study in a Case of Morphea Cover

A Polarized Light Microscopy Study in a Case of Morphea

Open Access
|Apr 2021

Abstract

We report a case of plaque type of scleroderma with specific clinical features and conventional histopathology, with sclerosis and hipocellularity of fibroblasts and preservation of elastic tissue. We describe polarized light microscopy findings, on conventional stained slides and on picro sirius red stained slides. We appreciate that picro sirius red stain allows a better characterization of collagen fibres composition in papillary and reticular dermis, that is severely disturbed in morphea, with an inverse distribution of collagen fibres type I and III comparative with normal dermis.

DOI: https://doi.org/10.2478/arsm-2020-0001 | Journal eISSN: 1841-4036 | Journal ISSN: 1223-9666
Language: English
Page range: 1 - 4
Published on: Apr 22, 2021
Published by: Ovidius University of Constanta
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2021 Mocanu Liliana, Deacu Sorin, Roman Polimaru, Aschie Mariana, published by Ovidius University of Constanta
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.