Skip to main content
Have a personal or library account? Click to login
Alphafold Modeling and Molecular Docking of Pseudomonas fluorescens Cutinase with Agrochemicals Cover

Alphafold Modeling and Molecular Docking of Pseudomonas fluorescens Cutinase with Agrochemicals

Open Access
|Apr 2026

References

  1. de Oliveira, M. V. D., Calandrini, G., da Costa, C. H. S., da Silva de Souza, C. G., Alves, C. N., Silva, J. R. A., Lima, A. H., Lameira, J. (2025). Evaluating cutinase from Fusarium oxysporum as a biocatalyst for the degradation of nine synthetic polymer. Scientific Reports, 15(1), 2887. DOI: 10.1038/s41598-024-84718-0
  2. Arya, G. C., Sarkar, S., Manasherova, E., Aharoni, A., & Cohen, H. (2021). The plant cuticle: an ancient guardian barrier set against long-standing rivals. Frontiers in plant science, 12, 663165. DOI: 10.3389/fpls.2021.663165
  3. Martínez, A., & Maicas, S. (2021). Cutinases: Characteristics and Insights in Industrial Production. Catalysts, 11(10), 1194. DOI: 10.3390/catal11101194
  4. Sahu, S., Kaur, A., Khatri, M., Singh, G., & Arya, S. K. (2023). A review on cutinases enzyme in degradation of microplastics. Journal of Environmental Management, 347, 119193. DOI: 10.1016/j.jenvman.2023.119193
  5. Fett, W., Wijey, C., Moreau, R., & Osman, S. (2000). Production of cutinolytic esterase by filamentous bacteria. Letters in applied microbiology, 31(1), 25-29. DOI: 10.1046/j.1472-765x.2000.00752.x
  6. Dutta,K., Krishnamoorthy, H., & Dasu, V. V. (2013). Novel cutinase from Pseudomonas cepacia NRRL B 2320: Purification, characterization and identification of cutinase encoding genes. The Journal of General and Applied Microbiology, 59(3), 171-184. DOI: 10.2323/jgam.59.171
  7. Rhee, H.-K., Nam, I.-S., & Park, J. M. (2006). New Developments and Application in Chemical Reaction Engineering: Proceedings of the 4th Asia-Pacific Chemical Reaction Engineering Symposium (APCRE ’ 05), Gyeongju, Korea, June 12-15 2005: Elsevier.
  8. Olowe, O. M., Akanmu, A. O., & Asemoloye, M. D. (2020). Exploration of microbial stimulants for induction of systemic resistance in plant disease management. Annals of Applied Biology, 177(3), 282-293. DOI: 10.1111/aab.12631
  9. Bakli, M., & Zenasni, A. (2019). Isolation of fluorescent Pseudomonas Spp. Strains From rhizosphere agricultural soils and assessment of their role in plant growth and phytopathogen biocontrol. Research Journal of Agricultural Science, 51(1), 20-29. https://rjas.ro/issue_detail/48
  10. Pio, T. F., & Macedo, G. A. (2009). Cutinases:: Properties and Industrial Applications. Advances in applied microbiology, 66, 77-95. DOI: 10.1016/S0065-2164(08)00804-6
  11. de Oliveira, C. T., de Assis, M. A., Mazutti, M. A., Pereira, G. A. G., & de Oliveira, D. (2023). Production of recombinant cutinases and their potential applications in polymer hydrolysis: The current status. Process biochemistry, 134, 30-46. DOI: 10.1016/j.procbio.2023.10.020
  12. Bakli, M., Pascalau, R., & Smuleac, L. (2020). Rare codon analysis in Rickettsia affecting recombinant protein expression in Escherichia coli. Adv Res Life Sci, 4, 30-35. DOI: 10.2478/arls-2020-0015
  13. Bakli, M., Karim, L., Mokhtari-Soulimane, N., Merzouk, H., & Vincent, F. (2020). Biochemical characterization of a glycosyltransferase Gtf3 from Mycobacterium smegmatis: a case study of improved protein solubilization. 3 Biotech, 10(10), 1-13. DOI: 10.1007/s13205-020-02431-x
  14. Jumper, J., Evans, R., Pritzel, A., Green, T., Figurnov, M., Ronneberger, O., Tunyasuvunakool, K., Bates, R., Žídek, A., Potapenko, A. (2021). Highly accurate protein structure prediction with AlphaFold. nature, 596(7873), 583-589. DOI: 10.1038/s41586-021-03819-2
  15. Heo, L., Park, H., & Seok, C. J. N. a. r. (2013). GalaxyRefine: Protein structure refinement driven by side-chain repacking. 41(W1), W384-W388. DOI: 10.1093/nar/gkt458
  16. Laskowski, R. A., MacArthur, M. W., Moss, D. S., & Thornton, J. M. J. J. o. a. c. (1993). PROCHECK: a program to check the stereochemical quality of protein structures. 26(2), 283-291. DOI: 10.1107/S0021889892009944
  17. Liu, Y., Yang, X., Gan, J., Chen, S., Xiao, Z.-X., & Cao, Y. J. N. a. r. (2022). CB-Dock2: Improved protein– ligand blind docking by integrating cavity detection, docking and homologous template fitting. 50(W1), W159-W164. DOI: 10.1093/nar/gkac394
  18. Bakli, M., Paşcalău, R., Bouras, N., & Smuleac, L. (2021). In silico characterization of a cutinase from Pseudomonas fluorescens. Research Journal of Agricultural Science, 53(3), 11-20. https://rjas.ro/paper_detail/3473
  19. Cao, Y., & Li, L. (2014). Improved protein–ligand binding affinity prediction by using a curvature-dependent surface-area model. Bioinformatics, 30(12), 1674-1680. DOI: 10.1093/bioinformatics/btu104
  20. Walz, I., & Schwack, W. (2007). Cutinase inhibition by means of insecticidal organophosphates and carbamates. 3. Oxidation of phosphorothionates by chloroperoxidase from Caldariomyces fumago. Journal of agricultural and food chemistry, 55(20), 8177-8186. DOI: 10.1021/jf071598y.
Language: English
Page range: 48 - 53
Submitted on: May 1, 2025
Accepted on: Dec 1, 2025
Published on: Apr 2, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: Volume open

© 2026 Mahfoud Bakli, Rayene Amini, Raul Paşcalău, Laura Șmuleac, Monica Dragomirescu, published by University of Life Sciences “King Mihai I“ from Timisoara
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.