Effect of Diet Supplemented with Dennettia tripetala Fruits on Serum Antioxidants and Biochemical Parameters of Albino Rats

Adebiyi H. Yetunde; Dauda Muhammed; Babatunde O. Richard; Odey O. Bernard; Aderemi C. Omolaiye; Suleiman I. Onoruoiza

doi:10.2478/arls-2020-0013

Abstract

This study was carried out to determine the effect of dietary supplementation of Dennettia tripetala on some biochemical parameters of rats. Twenty-five rats were used and were divided in to five groups of 5 rats. Group 1 served as control while group 2-5 were fed dietary inclusion of Dennettia tripetala fruits for 28 days. After the feeding trials, the rats were sacrificed and blood was collected for biochemical analyses. The serum concentration triglyceride and glucose were significantly lowered (p<0.05) while total protein, catalase and high-density lipoprotein were significantly higher (p<0.05) in rats fed with the formulated diet. There was no significant difference (p<0.05) in the serum level of superoxide dismutase, albumin, cholesterol and low-density lipoprotein of rats fed with the formulated diet. In conclusion, the study has shown that dietary inclusion of Dennettia tripetala fruits has hypoglycaemic, antioxidant and hypolipidemic effect. Therefore, it may help in the prevention of coronary heart disease, diabetes mellitus and cancer.

References

1. Okwu, D. E. & Morah, F. N. I. (2005). Isolation and Characterization of Phenanthrenic Alkaloid Uvariopsine from Dennettia tripetala Fruits. Journal of medicinal and aromatic plant science, 27, 496 – 498.
Search in Google Scholar Back to article
2. Achinewhu, S. C., Ogbonna, C. C. & Hart, A. D. (1995). Chemical Composition of Indigenous Wild Herbs, Spices, Fruits, Nuts and Leafy Vegetables used as Food. Plant Foods for Human Nutrition, 48(4), 341–348.
Search in Google Scholar Back to article
3. Ejechi, B.O. & Akpomedaye, D. (2005). Activity of Essential Oil and Phenolic Extract of Pepper Fruits, DennettiatripetalaG. Baker Against Some Food-born Microorganisms. African Journal of Biotechnology, 3, 258-261.
Search in Google Scholar Back to article
4. Okwu, D. E. & Morah, F. N. I. (2004). Mineral and Nutritive Value of DennettiatripetalaFruits. Fruits, 59, 437-442.
Search in Google Scholar Back to article
5. Iwu, M. (1989). Food for medicine, in Dietary Plants And Masticastors as Sources of Biologically Active Substances. University of Ife Press, Ife, Nigeria, pp. 303–310.
Search in Google Scholar Back to article
6. Bright, E., Mfem, C., Ugumanim, A. & Ukpong, M. (2017). The Effect of Ethanol Extract of Dennettia tripetala (Pepper fruit) on Gastric Acid Secretion in Wistar Rats. Journal of Medical and Health Sciences, 6(3), 21-26.
Search in Google Scholar Back to article
7. Ikpi, D. E. & Nku, O. (2008). Effect of Ethanolic Extract of Dennettia tripetala Fruit on Haematological Parameters in Albino Wistar Rats. Nigerian Journal of Physiological Sciences, 23, 13–17.
Search in Google Scholar Back to article
8. Achinewhu, S. G., Ogbonna, C. & Hard, A. D. (1995). Chemical Composition of Indigenous Wild Herbs, Spices, Fruits, Nuts and Leafy Vegetables used as Food. Plants Food for Human Nutrition, 48, 341–348.
Search in Google Scholar Back to article
9. Dike, M.C. (2010). Proximate, Phytochemical and Nutrient Compositions of Some Fruits, Seeds and Leaves of Some Plant Species at Umudike, Nigeria. Journal of Agricultural and Biological Science, 5(1), 7-16.
Search in Google Scholar Back to article
10. Chipurara, B. (2010). Nutritional Content, Phenolic Compounds Composition and Antioxidant Activities of Selected Indigenous Vegetables of Zimbabwe. A Thesis Submitted to the Institute of Food, Nutrition and Family Sciences, Faculty of Science, University of Zimbabwe. pp 25-31.
Search in Google Scholar Back to article
11. Udeme, J.O., Kpobari, W.N., Joyce, O.A. & Augustine, A.U. (2013). Proximate, Phytochemical and Mineral Composition of Some Edible Fruits Grown in Oil Producing Community of River State, Nigeria. IOSR Journal of Environmental Science, Toxicology and Food Technology, 5(2), 38-46.
Search in Google Scholar Back to article
12. Pugalenthi, M., Vadivel, V., Gurumoorthi, P. & Janardhanan, K. (2004). Comparative Nutritional Evaluation of Little Known Legumes, Tamarindus indica, Erythrina indica and Sesbania bispinosa. Tropical and Subtropical Agroecosystem, 4, 107-123.
Search in Google Scholar Back to article
13. Egharevba, H. O. & Idah, E. A. (2015). Major Compounds from the Essential Oil of the Fruit and Comparative Phytochemical Studies of the Fruits and Leaves of Dennettia tripetala Barker F. Found in North Central Nigeria. International Journal of Pharmacognosy and Phytochemical Research, 7(6), 1262-1266.
Search in Google Scholar Back to article
14. Perkins-Veazie, P.M., Collins, J.K. & Robert, W. (2005). Screening Carotenoid Content in Seeded and Seedless Watermelon Fruit. Journal of Horticultural Science, 39, 830.
Search in Google Scholar Back to article
15. Amusa, N.A., Ashaye, O.E. & Oladapo, M.O. (2003). Biodeterioration of Proximate Composition of African Star Apple in Storage and Effects on its Food Value. African Journal of Biotechnology, 2(3), 56-59.
Search in Google Scholar Back to article
16. Olesen, M. & Gudman, H.E. (2000). Efficacy, Safety and Tolerability of Fructooligosaccharides in the Treatment of Irritable Bowel Syndrome. American Journal of Clinical Nutrition, 72,1570-1575.
Search in Google Scholar Back to article

Effect of Diet Supplemented with Dennettia tripetala Fruits on Serum Antioxidants and Biochemical Parameters of Albino Rats

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