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A Literature Review on the Global Burden and Impact of Substandard and Falsified Medicine Cover

A Literature Review on the Global Burden and Impact of Substandard and Falsified Medicine

Annals of Public Health Issues
Volume 2 (2022): Issue 1 (January 2022)
By: Olanrewaju Olamide Popoola,  Gulshan Madhur,  Mariam Medhat Mehrim,  Mark Odhiambo Omondi,  Priscilla Owusu-Mensah,  Saurabh Ashok Mamtani and  Alison Ubong Etukakpan  
Open Access
|Mar 2022

References

  1. [1] World Health Organization. A Study on the Public Health and Socioeconomic Impact of Substandard and Falsified Medical Products. Geneva, Switzerland: World Health Organization; 2017.
    Search in Google ScholarBack to article
  2. [2] World Health Organization. WHO Global Surveillance and Monitoring System for Substandard and Falsified Medical Products. Geneva, Switzerland: World Health Organization; 2017.
    Search in Google ScholarBack to article
  3. [3] Almuzaini T, Choonara I, Sammons H. Substandard and counterfeit medicines: a systematic review of the literature. BMJ Open. 2013;3:e002923.10.1136/bmjopen-2013-002923
    Search in Google ScholarBack to article
  4. [4] Medical Product Alert N°4/2020. Falsified Chloroquine circulating in the WHO region of Africa. World Health Organization (WHO). https://www.who.int/news-room/detail/09-04-2020-medical-product-alert-n4-2020.
    Search in Google ScholarBack to article
  5. [5] Substandard and falsified medical products. World Health Organization (WHO). https://www.who.int/news-room/fact-sheets/detail/substandard-and-falsified-medical-products. Published Jan. 2018. Accessed 20 May 2020.
    Search in Google ScholarBack to article
  6. [6] Newton PN, Tabernero P, Dwivedi P, Culzoni MJ, Monge ME, et al. Falsified medicines in Africa: all talk, no action. Lancet. 2014;2:e509-510. https://www.thelancet.com/action/showPdf?pii=S2214-109X%2814%2970279-7. Published Sep 2014. Accessed 25 May 2020.10.1016/S2214-109X(14)70279-7
    Search in Google ScholarBack to article
  7. [7] Bate R, Jensen P, Hess K, Mooney L, Milligan J. Substandard and falsified anti-tuberculosis drugs: a preliminary field analysis. Int J Tuberc Lung Dis. 2013;17(3):308-311.10.5588/ijtld.12.035523321423
    Search in Google ScholarBack to article
  8. [8] Blackstone EA, Fuhr JP, Pociask MA. The Health and Economic Effects of Counterfeit Drugs. Am Health Drug Benefits. 2014;7(4):216-224.
    Search in Google ScholarBack to article
  9. [9] Bekoe SO, Ahiabu M, Orman E, Tersbøl BP, Adosraku RK, et al. Exposure of consumers to substandard antibiotics from selected authorized and unauthorized medicine sales outlets in Ghana. Trop Med Int Health. 2020;25(8):962-975.10.1111/tmi.1344232418294
    Search in Google ScholarBack to article
  10. [10] Schiavetti B, Wynendaele E, De Spiegeleer B, Mbinze GJ, Kalenda N, et al. The Quality of Medicines Used in Children and Supplied by Private Pharmaceutical Wholesalers in Kinshasa, Democratic Republic of Congo: A Prospective Survey. Am J Trop Med Hyg. 2018;98(3):894-903.10.4269/ajtmh.17-0732593090929313479
    Search in Google ScholarBack to article
  11. [11] Antignac M, Diop BI, Macquart de Terline D, Bernard M, Do B, Ikama SM, et al. Fighting fake medicines: First quality evaluation of cardiac drugs in Africa. Int J Cardiol. 2017;243:523-528.10.1016/j.ijcard.2017.04.09928641892
    Search in Google ScholarBack to article
  12. [12] Schäfermann S, Hauk C, Wemakor E, Neci R, Mutombo G, et al. Substandard and Falsified Antibiotics and Medicines against Noncommunicable Diseases in Western Cameroon and North-eastern Democratic Republic of Congo. Am J Trop Med Hyg. 2020;103(2):894-908.10.4269/ajtmh.20-0184741042732394884
    Search in Google ScholarBack to article
  13. [13] Khurelbat D, Dorj G, Sunderland B, Sanjjav T, Bayarsaikhan E, et al. A cross-sectional analysis of falsified, counterfeit and substandard medicines in a low-middle income country. BMC Public Health. 2020;20:743.10.1186/s12889-020-08897-x724093432434489
    Search in Google ScholarBack to article
  14. [14] Sammons MH, Choonara I. Substandard medicines: a greater problem than counterfeit medicines? BMJ Paediatrics Open. 2017;1:e000007.10.1136/bmjpo-2017-000007584298729637090
    Search in Google ScholarBack to article
  15. [15] Smith RM, Schaefer MK, Kainer MA, et al. Fungal infections associated with contaminated methylprednisolone injections. N Engl J Med. 2013;368:1598–609.10.1056/NEJMoa121397823252499
    Search in Google ScholarBack to article
  16. [16] Abril JL, Holt DW, Wilson RR. Falsified Medicines in the European Union and North America: What are we doing to Protect Public Health? J Pharmacovigil. 2016;4:213.10.4172/2329-6887.1000213
    Search in Google ScholarBack to article
  17. [17] Loewenberg S. Combating counterfeit drugs. Lancet. 2008;371(9624):1551.10.1016/S0140-6736(08)60663-7
    Search in Google ScholarBack to article
  18. [18] Beargie SM, Higgins CR, Evans DR, Laing SK, Erim D, Ozawa S. The economic impact of substandard and falsified antimalarial medications in Nigeria. PLoS One. 2019;14(8):e0217910.10.1371/journal.pone.0217910669514831415560
    Search in Google ScholarBack to article
  19. [19] Wertheimer A, Chaney N, Santella T. Counterfeit Pharmaceuticals: Current Status and Future Projections. J Am Pharm Assoc. 2003;43(6):710-718.10.1331/15443450332264264214717268
    Search in Google ScholarBack to article
  20. [20] Schep LJ, Slaughter RJ, Temple WA, Beasley G. Diethylene glycol poisoning. Clin Toxicol. 2009;47(6):525-535.10.1080/1556365090308644419586352
    Search in Google ScholarBack to article
  21. [21] Rahman M, Yoshida N, Tsuboi H, Tomizu N, Endo J, Miyu O, Akimoto Y, Kimura K. The health consequences of falsified medicines-A study of the published literature. Trop Med Int Health. 2018;23(12):1294-1303.10.1111/tmi.1316130291683
    Search in Google ScholarBack to article
  22. [22] World Health Organisation. Growing threat from counterfeit medicines. Geneva, Switzerland: World Health Organization. 2010;88:245–246. doi:10.2471/BLT.10.010410.10.2471/BLT.10.010410
    Search in Google ScholarBack to article
  23. [23] Kelesidis T. Falagas M. Substandard/Counterfeit Antimicrobial Drugs. Clin Microbiol Rev. 2015;28(2):443-464.10.1128/CMR.00072-14440295825788516
    Search in Google ScholarBack to article
  24. [24] Lubell Y, Dondorp A, Guérin P, Drake T, Meek S, et al. Artemisinin resistance – modelling the potential human and economic costs. Malar J. 2014;13(1):452.10.1186/1475-2875-13-452425418725418416
    Search in Google ScholarBack to article
  25. [25] Wheelock A, Miraldo M, Parand A, Vincent C, Sevdalis N. Journey to vaccination: a protocol for a multinational qualitative study. BMJ Open. 2014;4(1):004279.10.1136/bmjopen-2013-004279391320524486678
    Search in Google ScholarBack to article
  26. [26] Gostin L, Buckley G, Kelley P. Stemming the Global Trade in Falsified and Substandard Medicines. JAMA. 2013;309(16):1693.10.1001/jama.2013.3048
    Search in Google ScholarBack to article
  27. [27] Ozawa S, Evans DR, Bessias S, Haynie DG, YemekeTT, et al. Prevalence and Estimated Economic Burden of Substandard and Falsified Medicines in Low-and Middle-Income Countries. A Systematic Review and Meta-analysis. JAMA Network Open. 2018;1(4):6-10.10.1001/jamanetworkopen.2018.1662
    Search in Google ScholarBack to article
  28. [28] Przyswa E. Counterfeit Medicnes and Criminal Organisations. IRACM. 2013:14.
    Search in Google ScholarBack to article
  29. [29] World Economic Forum. Global Risks 2011, Sixth Edition, An Initiative of the Risk Response Network. Geneva, Switzerland: World Economic Forum; 2011:111.
    Search in Google ScholarBack to article
  30. [30] Acri, Kristina ML. Pharmaceutical Counterfeiting: Endagering Public Health, Society, and the Economy. Fraser Institute. 2018:20-36.
    Search in Google ScholarBack to article
  31. [31] Aminu N, Sha’aban A, Abubakar A, Gwarzo M. Unveiling the peril of substandard and falsified medicines to public health and safety in Africa: Need for all-out war to end the menace. Med Access Point Care. 2017;1(1): e145-e154.10.5301/maapoc.0000023
    Search in Google ScholarBack to article
  32. [32] Findlay B. Counterfeit drugs and national security. Washington (DC): The Stimson Center. 2011.
    Search in Google ScholarBack to article
  33. [33] Pisani E. Antimicrobial resistance: What does medicine quality have to do with it? AMR Review. 2015. URL: https://amr-review.org/sites/default/files/ElizabethPisaniMedicinesQualitypaper.pdf. Published Sep. 2015. Accessed 19 May 2020.
    Search in Google ScholarBack to article
  34. [34] Buckley GJ, Gostin LO, eds. Counterfeiting the Problem of Falsified and Substandard Drugs. Washington (DC): National Academy Press (US); 2013.10.17226/18272
    Search in Google ScholarBack to article
  35. [35] Ghanem N. Substandard and Falsified Medicines: Global and Local Efforts to Address a Growing Problem. Pharm J. 2019. URL: https://www.pharmaceutical-journal.com/research/perspective-article/substandard-and-falsified-medicines-global-and-local-efforts-to-address-a-growing-problem/20206309.article?firstPass=false. Published May 2019. Accessed 23 May 2020.
    Search in Google ScholarBack to article
  36. [36] Bumpass J, Bestch E. Exploratory study on active pharmaceutical ingredient manufacturing for essential medicines (English). Health, Nutrition and Population (HNP) discussion paper. Washington, DC: World Bank. 2009. URL: http://documents.worldbank.org/curated/en/848191468149087035/Exploratory-study-on-active-pharmaceutical-ingredient-manufacturing-for-essential-medicines. Accessed 26 May 2020.
    Search in Google ScholarBack to article
  37. [37] Glass B. Counterfeit Drugs and Medical Devices in Developing Countries. Res Rep Trop Med. 2014;5:11-22.10.2147/RRTM.S39354
    Search in Google ScholarBack to article
  38. [38] Funestrand H, Liu R, Lundin S, Troein M. Substandard and falsified medical products are a global public health threat. A pilot survey of awareness among physicians in Sweden. Int J Public Health. 2018;41(1):e95-e102.10.1093/pubmed/fdy092
    Search in Google ScholarBack to article
  39. [39] Wiegard A, Heuermann M. The Role of the German Official Drug Investigation Bodies in Combating Counterfeit Medicines. Bundesgesundheitsbl. 2017;60:1214-1220.10.1007/s00103-017-2624-8
    Search in Google ScholarBack to article
  40. [40] Smith G, Smith JA, Brindley DA. The Falsified Medicines Directive: How to secure your supply chain. J Generic Med. 2015;11(3–4):169–172.10.1177/1741134315588986
    Search in Google ScholarBack to article
  41. [41] United States Pharmacopeia (USP) Global Public Policy Position: Combatting Substandard and Falsified Medicines. Rocksville, United States of America; 2017. URL: https://www.google.com/url?sa=t&source=web&rct=j&url=https://www.usp.org/sites/default/files/usp/document/about/public-policy/combatting-substandard-and-falsified-medicines-policy-position.pdf&ved=2ahUKEwjestH53uPpAhUGDmMBHSIcB6MQFjAAegQICRAB&usg=AOvVaw0P4L6CkEgJ7JL963jONWp1. Published July 2017. Accessed 25 May, 2020.
    Search in Google ScholarBack to article
  42. [42] Mackey TK, Liang BA, York P, Kubic T. Counterfeit Drug Penetration into Global Legitimate Medicine Supply Chains: A Global Assessment. Am J Trop Med Hyg. 2015;92(6):59-67. Doi:10.4269/ajtmh.14-0389.10.4269/ajtmh.14-0389
    Search in Google ScholarBack to article
  43. [43] Newton PN, Bond KC. COVID-19 and risks to the supply and quality of tests, drugs, and vaccines. Lancet. 2020;8(6):e754-e755.10.1016/S2214-109X(20)30136-4
    Search in Google ScholarBack to article
DOI: https://doi.org/10.2478/aphi-2022-0003 | Journal eISSN: 2720-1961
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Language: English
Page range: 16 - 31
Submitted on: Sep 29, 2021
Accepted on: Nov 23, 2021
Published on: Mar 22, 2022
Published by: Sciendo
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
Keywords:
Substandard,
counterfeit,
falsified medicines,
strategies
Related subjects:
Medicine,
Clinical medicine,
Public health,
Pharmacy,
Pharmacy, other,
Social sciences,
Sociology,
Sociology, other,
Education,
Education, other

© 2022 Olanrewaju Olamide Popoola, Gulshan Madhur, Mariam Medhat Mehrim, Mark Odhiambo Omondi, Priscilla Owusu-Mensah, Saurabh Ashok Mamtani, Alison Ubong Etukakpan, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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