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Digital workflow to fabricate a 3D-printed monobloc mandibular advancement appliance for primary snoring and obstructive sleep apnoea Cover

Digital workflow to fabricate a 3D-printed monobloc mandibular advancement appliance for primary snoring and obstructive sleep apnoea

Open Access
|Jul 2025

References

  1. De Meyer MM, Vanderveken OM, De Weerdt S, Marks LA, Cárcamo BA, Chavez AM, et al. Use of mandibular advancement devices for the treatment of primary snoring with or without obstructive sleep apnoea (OSA): a systematic review. Sleep Medicine Reviews. 2021;56:101407.
  2. Levine M, Cantwell M, Postol K, Schwartz D. Dental sleep medicine standards for screening, treating, and management of sleep-related breathing disorders in adults using oral appliance therapy. J Dent Sleep Med. 2022;9:
  3. Lim J, Lasserson TJ, Fleetham J, Wright JJ. Oral appliances for obstructive sleep apnoea. Cochrane database of systematic reviews. 2006;
  4. Mogell K, Blumenstock N, Mason E, Rohatgi R, Shah S, Schwartz D. Definition of an effective oral appliance for the treatment of obstructive sleep apnoea and snoring: an update for 2019. J Dent. Sleep Med. 2019;6:
  5. Sankri-Tarbichi AG. Obstructive sleep apnoea-hypopnoea syndrome: Etiology and diagnosis. Avicenna J Med. 2012;2:3–8.
  6. Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MS, Morrell MJ, et al. Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. The Lancet respiratory medicine. 2019;7:687–98.
  7. Blumen M, Salva MQ, d’Ortho MP, Leroux K, Audibert P, Fermanian C, et al. Effect of sleeping alone on sleep quality in female bed partners of snorers. European Respiratory Journal. 2009;34:1127–31.
  8. Yu M, Ma Y, Gong XU, Gao X. Dental And Skeletal Changes Of Long-Term Use Of Mandibular Advancement Devices For The Treatment Of Adult Obstructive Sleep Apnoea: A Systematic Review And Meta-Analysis. Journal of Evidence-Based Dental Practice. 2024;24:101991.
  9. Stuck BA, Dreher A, Heiser C, Herzog M, Kühnel T, Maurer JT et al. Diagnosis and treatment of snoring in adults–S2k Guideline of the German Society of Otorhinolaryngology, Head and Neck Surgery. Sleep Breathing. 2015;19:135–48.
  10. Maguire J, Steele JG, Gibson GJ, Wilson JA, Steen N, McCracken GI. Randomised cross‐over study of oral appliances for snoring. Clinical Otolaryngology. 2010;35:204–9.
  11. Sullivan F. Hidden health crisis costing America billions: underdiagnosing and undertreating obstructive sleep apnoea draining healthcare system. Darien (IL): American Academy of Sleep Medicine; 2016. Accessed December 20, from https://aasm. org/resources/pdf/sleep-apnoea-economic-crisis.pdf
  12. Chan AS, Sutherland K, Schwab RJ, Zeng B, Petocz P, Lee RW et al. The effect of mandibular advancement on upper airway structure in obstructive sleep apnoea. Thorax. 2010;65:726–32.
  13. Kyung SH, Park YC, Pae EK. Obstructive sleep apnoea patients with the oral appliance experience pharyngeal size and shape changes in three dimensions. The Angle Orthodontist. 2005;75:15–22.
  14. Ramar K, Dort LC, Katz SG, Lettieri CJ, Harrod CG, Thomas SM, et al. Clinical practice guideline for the treatment of obstructive sleep apnoea and snoring with oral appliance therapy: an update for 2015: an American Academy of Sleep Medicine and American Academy of Dental Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2015;11:773–827.
  15. Sheats RD. Management of side effects of oral appliance therapy for sleep-disordered breathing: summary of American Academy of Dental Sleep Medicine recommendations. J Clin Sleep Med. 2020;16:835-.
  16. NextDent. NextDent OrthoFlex. NextDent;Accessed December 20, 2024. https://nextdent.com/products/nextdent-ortho-flex/
  17. Graf S, Tarraf NE, Vasudavan S. Direct printed removable appliances: A new approach for the Twin-block appliance. Am J Orthod Dentofacial Orthop. 2022;162:103–7.
  18. Meurice JC, Marc I, Carrier G, Sériès F. Effects of mouth opening on upper airway collapsibility in normal sleeping subjects. Am J Resp Critical Care Med. 1996;153:255–9.
  19. Ishiyama H, Hasebe D, Sato K, Sakamoto Y, Furuhashi A, Komori E, et al. The efficacy of device designs (mono-block or bi-block) in oral appliance therapy for obstructive sleep apnoea patients: a systematic review and meta-analysis. Int J Environment Res Public Health. 2019;16:3182.
  20. Bartolucci ML, Bortolotti F, Corazza G, Incerti Parenti S, Paganelli C, Alessandri Bonetti G. Effectiveness of different mandibular advancement device designs in obstructive sleep apnoea therapy: A systematic review of randomised controlled trials with meta‐ analysis. J Oral Rehab. 2021;48:469–86.
  21. Jawahar A, Maragathavalli G. Applications of 3D printing in dentistry–a review. J Pharmaceutical Sci Res. 2019;11:1670–5.
  22. Pillai S, Upadhyay A, Khayambashi P, Farooq I, Sabri H, Tarar M, et al. Dental 3D-printing: transferring art from the laboratories to the clinics. Polymers. 2021;13:157.
  23. Bartolucci ML, Bortolotti F, Raffaelli E, D’Antò V, Michelotti A, Alessandri Bonetti G. The effectiveness of different mandibular advancement amounts in OSA patients: a systematic review and meta-regression analysis. Sleep Breathing. 2016;20:911–9.
  24. Chin MH, Lau MN, Saleh Fayed MM, Govindaraju R, Kulasegarah J. Efficacy of mandibular advancement appliances at different mandibular protrusions for obstructive sleep apnoea: a randomised controlled trial [master’s thesis]. Kuala Lumpur: Universiti Malaya; 2023. Unpublished
  25. Guttridge C, Shannon A, O’Sullivan A, O’Sullivan KJ, O’Sullivan LW. Biocompatible 3D printing resins for medical applications: A review of marketed intended use, biocompatibility certification, and post-processing guidance. Ann 3D Printed Med. 2022;5: 100044.
DOI: https://doi.org/10.2478/aoj-2025-0019 | Journal eISSN: 2207-7480 | Journal ISSN: 2207-7472
Language: English
Page range: 256 - 267
Submitted on: Feb 1, 2025
Accepted on: May 1, 2025
Published on: Jul 7, 2025
Published by: Australian Society of Orthodontists Inc.
In partnership with: Paradigm Publishing Services
Publication frequency: 1 times per year

© 2025 May Nak Lau, Kah Shin Ong, Cheng Lin Chong, Priyantha Lee Yek Pang, published by Australian Society of Orthodontists Inc.
This work is licensed under the Creative Commons Attribution 4.0 License.