Figure 1.
Figure 2.
Figure 3.
Figure 4.
Figure 5.
Summary of all aligner brands_
| Brand | Company | Country | Year Established | Official website | Clinicians | Patients | |
|---|---|---|---|---|---|---|---|
| 1 | 32 Watts Clear Aligners | India | 2018 | https://www.32watts.com/ | Y | ||
| 2 | 360美牙隐形矫正 | China | 2019 | http://www.360meiya.cn/ | Y | ||
| 3 | ACE Aligners | U.S. | N/A | acealigners.com | Y | ||
| 4 | AIRNIVOL | Italy | 2004 | https://www.airnivol.com/en | Y | ||
| 5 | Aligner Studio | U.S. | N/A | https://www.alignerstudio.com/ | Y | ||
| 6 | AlignerCo | U.S. | 2019 | https://www.alignerco.com/ | Y | ||
| 7 | Angelalign 时代天使隐形矫正 | Angelalign | China | 2003 | http://www.angelalign.com/ | Y | |
| 8 | Argen | U.S. | 2018 | https://argen.com/clear-aligners#/ | Y | ||
| 9 | byte | U.S. | 2018 | https://www.byteme.com/ | Y | ||
| 10 | CA Clear Aligner | Scheu-Dental | German | N/A | http://ca-clear-aligner.com/en/b2c/index.html | Y | |
| 11 | Candid CO | U.S. | 2017 | https://www.candidco.com/ | Y | ||
| 12 | Clarity Aligners | 3M | U.S. | 2018 | https://www.3m.com/3M/en_US/types-of-braces-and-treatment-us/clear-aligners/ | Y | |
| 13 | Clarus Clear Aligners | Egypt | N/A | http://www.clarusaligners.com/ | Y | ||
| 14 | Clear correct | Straumann | Switzerland | 2006 | https://www.straumann.com/clearcorrect/en/home.html | Y | |
| 15 | Insignia Clearguide System | Ormco | U.S. | 2012 | https://ormco.com/products/insignia-clearguide/ | Y | |
| 16 | Clearline Aligners | Canada | N/A | https://www.clearlinesmile.ca/ | Y | ||
| 17 | Clearlyaligners | U.S. | N/A | https://clearlyaligners.com/ | Y | ||
| 18 | ClearPath | U.S. | 2008 | https://www.clearpathdental.com/ | Y | ||
| 10 | ClearPath Orthodontics | Pakistan | 2007 | https://www.clearpathortho.com/ | Y | ||
| 20 | ClearSmile | IAS Orthodontics | UK | N/A | https://www.clearsmilealigner.com/ | Y | |
| 21 | ClearX | K Line Europe | German | N/A | https://www.clearxaligners.com/ | Y | |
| 22 | Coast Clear Aligners | Coast Dental & Orthodontics | U.S. | N/A | https://www.coastdental.com/aligners | Y | |
| 23 | ddhaim clear 디디하임 클리어 | Korea | N/A | http://ddhaim.com/ | Y | ||
| 24 | Dr. Clear aligner | Singapore | N/A | https://www.drclearaligners.com/ | Y | ||
| 25 | Easysmile | Easysmile | China | N/A | https://www.easysmile.com/ | Y | |
| 26 | ecligner 이클라이너 | Ecligner international | Korea | 1998 | http://www.ecligner.com/ | Y | |
| 27 | eon Aligners | U.S. | N/A | https://eonaligner.com/index.html | Y | ||
| 28 | EZ Smile Clear Aligners | Australia | N/A | https://www.ezsmile.com.au/ | Y | ||
| 29 | f22 Aligners | Italy | 2012 | https://www.f22aligner.com/ | Y | ||
| 30 | FrankSmile | UK | N/A | https://www.franksmile.co.uk/ | Y | ||
| 31 | Hibeauty 隐秀隐形矫正 | Hibeauty | China | 2012 | http://www.hibeauty.com/pt/index.htm | Y | |
| 32 | Inman Aligner | U.S. | 2001 | https://www.inmanaligner.com/ | Y | ||
| 33 | Invisalign | Align Technology | U.S. | 1998 | https://www.invisalign.com/ | Y | |
| 34 | iROK | iROK | China | 2009 | https://5ismile.com/ | Y | |
| 35 | JoyAligner | Singapore | N/A | http://joyaligner.com/ | Y | ||
| 36 | K Clear | K Line Europe GmbH | German | N/A | https://kline-europe.com/en/home | Y | |
| 37 | magicalign 正丽科技隐形矫正 | Magicalign | China | 2014 | http://www.magicalign.com/pc/index.html | Y | |
| 38 | MegaNeer 美加易齐隐形矫正 | Mega Neer | China | 2010 | http://www.mega-teeth.com/Products/yxzj/ | Y | |
| 39 | Noviclear | N/A | http://noviclear.com/ | Y | |||
| 40 | Nuvola | GEO Orthodontic | UK | N/A | http://www.geoorthodontic.com/ | Y | |
| 41 | ODS Aligners | India | N/A | https://odsaligners.com/ | Y | ||
| 42 | Orthocaps TwinAligner System | Ortho Caps GmbH | Germany | 2006 | https://www.orthocaps.com/ | Y | |
| 43 | OrthoClear | UK | 2005 | https://www.orthoclear.nl/en/ | Y | ||
| 44 | OrthoFX | U.S. | 2019 | https://www.orthofx.com/ | Y | ||
| 45 | OrthoSnap | U.S. | N/A | https://www.orthosnap.com/ | Y | ||
| 46 | Pure Smiles Online | Canada | N/A | https://www.puresmilesonline.com/ | Y | ||
| 47 | Refine Complete Aligner System | TP Orthodontics | U.S | 2017 | https://www.tportho.com/wp-content/uploads/2017/04/996-385ENG-Refine-B2B_2017_0W.pdf | Y | |
| 48 | reveal Clear Aligners | Henry Schein | U.S. | 2019 | https://www.henryschein.com/us-en/dental/supplies/reveal.aspx | Y | |
| 49 | RxAligners | UK | 2011 | http://rxaligners.com/ | Y | ||
| 50 | See-Through Aligner 시스루 얼라이너 | 시스루테그 | Korea | 2014 | http://www.saligner.com/ | Y | |
| 51 | simpli 5 | Ormco | U.S. | 2006 | https://ormco.com/products/simpli-5/ | Y | |
| 52 | Sino Dental Lab | Sino Dental Lab | China | N/A | http://www.sino-dental.com/cn/product-details-69.html | Y | |
| 53 | SLX Clear Aligners | Henry Schein | U.S. | 2018 | https://slxclearaligners.com/ | Y | |
| 54 | Smartee 正雅隐形矫正 | Smartee | China | 2004 | http://www.smartee.cn/ | Y | |
| 55 | Smile Direct Club | U.S. | 2014 | https://smiledirectclub.co.nz/en-nz/ | Y | ||
| 56 | Smile Love | U.S. | N/A | https://smilelove.com/ | Y | ||
| 57 | Smile Styler | Australia | N/A | https://www.smilestyler.com.au/ | Y | ||
| 58 | Smilealign 适乐美 | Smilealign | China | N/A | https://www.smilalign.cn/ | Y | |
| 59 | Smilelign | UK | 2012 | https://smilelign.com/ | Y | ||
| 60 | SmileTRU | U.S. | N/A | https://www.smiletru.com/ | Y | ||
| 61 | smilii | NZ | 2019 | https://www.smilii.co.nz/ | Y | ||
| 62 | SnapCorrect | U.S. | 2012 | https://snapcorrect.com/ | Y | ||
| 63 | Spark Clear Aligner System | Ormco | U.S. | 2019 | https://mysparksmile.com/ | Y | |
| 64 | Straight My Teeth | UK/Ireland | 2018 | https://www.straightmyteeth.com/ | Y | ||
| 65 | Straight Teeth Direct | UK | 2009 | https://www.straightteethdirect.com/ | Y | ||
| 66 | Straight28 Clear Aligners | U.S. | N/A | http://straight-28.com/ | Y | ||
| 67 | Strayt Clear aligners | U.S. | N/A | https://www.straytteeth.com/ | Y | ||
| 68 | SureSmile | Dentsply Sirona | U.S. | 1999 | https://www.suresmile.com/ | Y | |
| 69 | Trioclear | Hong Kong | 2020 | https://www.trioclear.com/ | Y | ||
| 70 | Uniform Teeth | U.S. | 2016 | https://www.uniformteeth.com/ | Y | ||
| 71 | V-Clear Aligners | India | N/A | http://www.vclearaligners.com/ | Y | ||
| 72 | Vincialign 达芬奇隐形矫正 | Vincialign | China | N/A | https://cn.vincialign.com/index/index | Y | |
| 73 | Whitesmile Clear | Malaysia | N/A | https://whitesmileclear.com/ | Y | ||
| 74 | Wonder Smile | Australia | 2016 | http://wondersmile.co.nz | Y | ||
| 75 | Zenyum | Singapore | N/A | https://www.zenyum.com/sg-en/ | Y |
Marketing claims found the official websites of the clear aligners companies included in the study_
| Marketing claim theme | Number of companies | Number of claims with evidence cited |
|---|---|---|
| Improved material | 42 | 4* |
| Better comfort | 50 | 1 |
| Shorter treatment time | 44 | Not Applicable |
| Enhanced aesthetics | 53 | 2 |
| Lower cost | 37 | Not Applicable |
| Others | 54 | 2 |