Have a personal or library account? Click to login
High-risk morphological features are less prevalent among small (<5mm) papillary thyroid microcarcinomas compared to larger (≥5mm) tumors: a study of 206 cases Cover

High-risk morphological features are less prevalent among small (<5mm) papillary thyroid microcarcinomas compared to larger (≥5mm) tumors: a study of 206 cases

Open Access
|Jul 2021

References

  1. 1. Ahn HS, Kim HJ, Welch HG. Korea’s thyroid-cancer “epidemic”-screening and overdiagnosis. N Engl J Med. 2014;371:1765-1767.10.1056/NEJMp140984125372084
  2. 2. Cramer JD, Fu PF, Harth KC et al. Analysis of the rising incidence of thyroid cancer using the Surveillance, Epidemiology and End Results national cancer data registry. Surgery. 2010;148: 1147-1152.10.1016/j.surg.2010.10.01621134545
  3. 3. Davies L,Welch HG. Current thyroid cancer trends in the United States. JAMA Otolaryngol Head Neck Surg. 2014;140:317-322.10.1001/jamaoto.2014.124557566
  4. 4. Pusztaszeri MP, Tamilia M, Payne RJ. Active surveillance for low-risk small papillary thyroid cancer in North American countries: past, present and future (bridging the gap between North American and Asian practices). Gland Surg. 2020;9:1685-1697.10.21037/gs-20-389766705233224846
  5. 5. Yan L, Blanco J, Reddy V et al. Clinicopathological features of papillary thyroid microcarcinoma with a diameter less than or equal to 5mm. Am J Otolaryngol. 2019;40:560-563.10.1016/j.amjoto.2019.05.00331103218
  6. 6. Zahan AE, Nechifor-Boilă AC, Paşcanu I, et al. Papillary Thyroid Microcarcinomas: a 25 Years Retrospective, Institutional Study of 255 Cases. Acta Marisiensis - Seria Medica. 2016;62:41-46.10.1515/amma-2015-0108
  7. 7. Welch HG. Cancer Screening, Overdiagnosis, and Regulatory Capture. JAMA Intern Med. 2017;177:915-916.10.1001/jamainternmed.2017.119828492850
  8. 8. Vaccarella S, Franceschi S, Bray F et al., Worldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis. N Engl J Med. 2016;375:614-617.10.1056/NEJMp160441227532827
  9. 9. Wang M, Wu WD, Chen GM, et al., Could Tumor Size Be A Predictor for Papillary Thyroid Microcarcinoma: a Retrospective Cohort Study. Asian Pac J Cancer Prev. 2015;16:8625-8628.10.7314/APJCP.2015.16.18.862526745127
  10. 10. Haugen BR, Alexander EK, Bible KC et al., 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016;26:1-133.10.1089/thy.2015.0020473913226462967
  11. 11. Gong Y, Li G, Lei J et al. A favorable tumor size to define papillary thyroid microcarcinoma: an analysis of 1176 consecutive cases. Cancer Manag Res. 2018;10:899-906.10.2147/CMAR.S154135593119929740219
  12. 12. Lim H, Devesa SS, Sosa JA, et al. Trends in Thyroid Cancer Incidence and Mortality in the United States, 1974-2013. JAMA. 2017;317:1338-1348.10.1001/jama.2017.2719821677228362912
  13. 13. Kaliszewski K, Diakowska D, Wojtczak B et al. Which papillary thyroid microcarcinoma should be treated as “true cancer” and which as “precancer”? World J Surg Oncol. 2019;17:91.
  14. 14. Liu C, Wang S, Zeng W et al. Total tumour diameter is superior to unifocal diameter as a predictor of papillary thyroid microcarcinoma prognosis. Sci Rep. 2017;7:1846.10.1038/s41598-017-02165-6543197228500312
  15. 15. Xu D, Lv X, Wang S et al. Risk factors for predicting central lymph node metastasis in papillary thyroid microcarcinoma. Int J Clin Exp Pathol. 2014;7:6199-205.
  16. 16. Virk RK, Van Dyke AL, Finkelstein A et al. BRAFV600E mutation in papillary thyroid microcarcinoma: a genotype-phenotype correlation. Mod Pathol. 2013;26:62-70.10.1038/modpathol.2012.15222918165
  17. 17. Jiang J, Lu H. Immediate Surgery Might Be a Better Option for Subcapsular Thyroid Microcarcinomas. Int J Endocrinol. 2019;2019:3619864.10.1155/2019/3619864647043531073306
  18. 18. Rosai J, Albores Saavedra J, Asioli S et al. Papillary thyroid carcinoma in Lloyd RV, Osamura RY, Klöppel G et al. (eds): WHO classification of tumours of endocrine organs. 4th edition. International Agency for Research on Cancer (IARC), Lyon, France, 2017, 81-91.
  19. 19. Sobin LH, Gospodarowicz MK, Wittekind C. UICC/TNM Classification of Malignant Tumors. 7th edition. John Wiley & Sons. Oxford, UK, 2009, 58-62.10.1002/9780471420194.tnmc08.pub2
  20. 20. Brierley JD, Gospodarowicz MK, Wittekind C. UICC/TNM Classification of Malignant Tumors. 8th edition. John Wiley & Sons. Oxford, UK, 2017, 51-55.10.1002/9780471420194.tnmc09.pub3
  21. 21. Niemeier LA, Akatsu HK, Song Chi et al. A combined molecular-pathologic score improves risk stratification of thyroid papillary microcarcinoma. Cancer. 2012;118:2069-2077.10.1002/cncr.26425322964921882177
  22. 22. Finkelstein A, Levy GH, Hui P et al. Papillary thyroid carcinomas with and without BRAF V600E mutations are morphologically distinct. Histopathology. 2012;60:1052-1059.10.1111/j.1365-2559.2011.04149.x22335197
  23. 23. Rossi ED, Bizzarro T, Martini M et al., Morphological parameters able to predict BRAF(V600E) -mutated malignancies on thyroid fine-needle aspiration cytology: Our institutional experience. Cancer Cytopathol. 2014;122:883-8891.10.1002/cncy.2147525156883
  24. 24. Wada N, Duh QY, Sugino K et al. Lymph node metastasis from 259 papillary thyroid microcarcinomas: frequency, pattern of occurrence and recurrence, and optimal strategy for neck dissection. Ann Surg. 2003;237:399-407.10.1097/01.SLA.0000055273.58908.19151431212616125
  25. 25. Shi C, Guo Y, Lv Y et al. Clinicopathological Features and Prognosis of Papillary Thyroid Microcarcinoma for Surgery and Relationships with the BRAFV600E Mutational Status and Expression of Angiogenic Factors. PLoS One. 2016;11:e0167414.10.1371/journal.pone.0167414514786927936049
  26. 26. Qian K, Guo K, Zheng X et al. Contrastive study of two screening criteria for active surveillance in patients with low-risk papillary thyroid microcarcinoma: a retrospective analysis of 1001 patients. Oncotarget. 2017;8:65836-65846.10.18632/oncotarget.19503563037629029476
  27. 27. Miyauchi A. Clinical Trials of Active Surveillance of Papillary Microcarcinoma of the Thyroid. World J Surg. 2016;40:516-522.10.1007/s00268-015-3392-y474621326744340
  28. 28. Zheng X, Peng C, Gao M et al. Risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: a study of 1,587 patients. Cancer Biol Med. 2019;16:121-130.10.20892/j.issn.2095-3941.2018.0125652846131119052
  29. 29. Lim YC, Choi EC, Yoon YH et al. Central lymph node metastases in unilateral papillary thyroid microcarcinoma. Br J Surg. 2009;96:253-257.10.1002/bjs.648419224514
  30. 30. Zhang L, Wei WJ, Ji QH et al. Risk factors for neck nodal metastasis in papillary thyroid microcarcinoma: a study of 1066 patients. J Clin Endocrinol Metab. 2012;97:1250-1257.10.1210/jc.2011-154622319042
  31. 31. Chang YW, Kim HS, Kim HY et al. Should central lymph node dissection be considered for all papillary thyroid microcarcinoma? Asian J Surg. 2016;39:197-201.
  32. 32. Lombardi CP, Bellantone R, De Crea C et al. Papillary thyroid microcarcinoma: extrathyroidal extension, lymph node metastases, and risk factors for recurrence in a high prevalence of goiter area. World J Surg. 2010;34:1214-1221.10.1007/s00268-009-0375-x20052467
  33. 33. Pelizzo MR, Boschin IM, Toniato A et al. Natural history, diagnosis, treatment and outcome of papillary thyroid microcarcinoma (PTMC): a mono-institutional 12-year experience. Nucl Med Commun. 2004;25:547-552.10.1097/01.mnm.0000126625.17166.3615167512
  34. 34. Song J, Yan T, Qiu W et al. Clinical Analysis of Risk Factors for Cervical Lymph Node Metastasis in Papillary Thyroid Microcarcinoma: A Retrospective Study of 3686 Patients. Cancer Manag Res. 2020;12:2523-2530.10.2147/CMAR.S250163715399832308489
  35. 35. Tallini G, De Leo A, Repaci A et al. Does the Site of Origin of the Microcarcinoma with Respect to the Thyroid Surface Matter? A Multicenter Pathologic and Clinical Study for Risk Stratification. Cancers (Basel). 2020;12:246.10.3390/cancers12010246701674331963890
  36. 36. Ryder M, Ghossein RA, Ricarte-Filho CM J et al. Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer. Endocr Relat Cancer. 2008;15:1069-1074.10.1677/ERC-08-0036264861418719091
  37. 37. Qing W, Fang WY, Ye L et al. Density of tumor-associated macrophages correlates with lymph node metastasis in papillary thyroid carcinoma. Thyroid. 2012;22:905-910.10.1089/thy.2011.0452342927322870901
  38. 38. Tao Y. Wang C, Li L et al. Clinicopathological features for predicting central and lateral lymph node metastasis in papillary thyroid microcarcinoma: Analysis of 66 cases that underwent central and lateral lymph node dissection. Mol Clin Oncol. 2017;6:49-55.10.3892/mco.2016.1085524485928123728
  39. 39. Brito JP, Ito Y, Miyauchi A et al. A Clinical Framework to Facilitate Risk Stratification When Considering an Active Surveillance Alternative to Immediate Biopsy and Surgery in Papillary Microcarcinoma. Thyroid. 2016;26:144-149.10.1089/thy.2015.0178484294426414743
  40. 40. Luo Y, Zhao Y, Chen K et al. Clinical analysis of cervical lymph node metastasis risk factors in patients with papillary thyroid microcarcinoma. J Endocrinol Invest. 2019;42:227-236.10.1007/s40618-018-0908-y639476629876836
DOI: https://doi.org/10.2478/amma-2021-0016 | Journal eISSN: 2668-7763 | Journal ISSN: 2668-7755
Language: English
Page range: 108 - 114
Submitted on: Mar 23, 2021
Accepted on: Apr 21, 2021
Published on: Jul 12, 2021
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year

© 2021 Emőke-Andrea Szász, Adela Nechifor-Boilă, Ancuța Zahan, Angela Borda, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.