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LC-MS Method for Determining Amiodarone and Desethylaminodarone in Rat Plasma Used in Endogenous Overdosing Conditions Following Lipolysis Cover

LC-MS Method for Determining Amiodarone and Desethylaminodarone in Rat Plasma Used in Endogenous Overdosing Conditions Following Lipolysis

Open Access
|Sep 2018

References

  1. 1. Schleifer JW, Sorajja D, Shen WK - Advances in the pharmacologic treatment of ventricular arrhythmias. Expert Opin Pharmacother. 2015;16(17):2637-51.10.1517/14656566.2015.110017026513538
  2. 2. Lu JT, Cai Y, Chen F, Jia WW, Hu ZY, Zhao YS - A Physiologically Based Pharmacokinetic Model of Amiodarone and its Metabolite Desethylamiodarone in Rats: Pooled Analysis of Published Data. Eur J Drug Metab Pharmacokinet. 2016 Dec;41(6):689-703.10.1007/s13318-015-0295-026254911
  3. 3. Roden AC, Camus P - Iatrogenic pulmonary lesions. Semin Diagn Pathol. 2018 Jul;35(4):260-271.10.1053/j.semdp.2018.03.00229631763
  4. 4. Schumacher JD, Guo GL - Mechanistic review of drug-induced steatohepatitis. Toxicol Appl Pharmacol. 2015 Nov 15;289(1):40-7.10.1016/j.taap.2015.08.022462885526344000
  5. 5. Santangeli P, Di Biase L, Burkhardt JD, Bai R, Mohanty P, Pump A, Natale A - Examining the safety of amiodarone. Expert Opin Drug Saf. 2012 Mar;11(2):191-214.10.1517/14740338.2012.66091522324910
  6. 6. Lafuente-Lafuente C, Alvarez JC, Leenhardt A, Mouly S, Extramiana F, Caulin C, Funck-Brentano C, Bergmann JF - Amiodarone concentrations in plasma and fat tissue during chronic treatment and related toxicity. Br J Clin Pharmacol. 2009 May;67(5):511-9.10.1111/j.1365-2125.2009.03381.x268606719552745
  7. 7. Shayeganpour A, Somayaji V, Brocks DR - A liquid chromatographymass spectrometry assay method for simultaneous determination of amiodarone and desethylamiodarone in rat specimens. Biomed Chromatogr. 2007 Mar; 21(3):284-90.10.1002/bmc.75417221913
  8. 8. Najjar TA - Disposition of amiodarone in rats after single and multiple intraperitoneal doses.Eur J Drug Metab Pharmacokinet. 2001 Jan- Jun;26(1-2):65-9.10.1007/BF0319037811554436
  9. 9. Binkhathlan Z, Somayaji V, Brocks DR, Lavasanifar A - Development of a liquid chromatography-mass spectrometry (LC/MS) assay method for the quantification of PSC 833 (Valspodar) in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Jun 15;869(1-2):31-7.10.1016/j.jchromb.2008.05.00318514043
  10. 10. Elsherbiny ME, El-Kadi AO, Brocks DR - The effect of betanaphthoflavone on the metabolism of amiodarone by hepatic and extrahepatic microsomes. Toxicol Lett. 2010 Jun 2;195(2-3):147-54.10.1016/j.toxlet.2010.03.01920362646
  11. 11. Najjar TA - Disposition of amiodarone in rats after single and multiple intraperitoneal doses. Eur J Drug Metab Pharmacokinet. 2001 Jan- Jun;26(1-2):65-9.10.1007/BF0319037811554436
  12. 12. Pathak RK, Mahajan R, Lau DH, Sanders P - The implications of obesity for cardiac arrhythmia mechanisms and management. Can J Cardiol. 2015 Feb;31(2):203-10.10.1016/j.cjca.2014.10.02725661555
  13. 13. Haley MJ, Mullard G, Hollywood KA, Cooper GJ, Dunn WB, Lawrence CB - Adipose tissue and metabolic and inflammatory responses to stroke are altered in obese mice. Disease Models & Mechanisms. 2017;10(10):1229-1243.10.1242/dmm.030411
DOI: https://doi.org/10.2478/amma-2018-0016 | Journal eISSN: 2668-7763 | Journal ISSN: 2668-7755
Language: English
Page range: 111 - 115
Submitted on: Jun 28, 2018
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Accepted on: Aug 16, 2018
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Published on: Sep 25, 2018
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2018 George Jîtcă, Bianca-Eugenia Ősz, Szende Vancea, Amalia Miklos, Amelia Tero-Vescan, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.