Unicompartmental Knee Arthroplasty: Current Surgical Approaches, Indications, Outcomes, and Future Perspectives
By: D. Buonsante and G. P. Georgiev
References
- Stoddart JC, Dandridge O, Garner A, et al. The compartmental distribution of knee osteoarthritis - a systematic review and meta-analysis. Osteoarthritis Cartilage, 2021, 29(4):445-455.
- D’Gasper D, Bains BS, Sadeghi H, et al. Comparing exercise prescription methods in knee osteoarthritis patients in Malaysia. Acta Medica Bulg, 2018, 45(1): 26-31.
- Vassileva D, Nedelcheva I, Mindova S, et al. The influence of gait patterns with aids on the patient’s recovery in the early period following total knee replacement. Acta Medica Bulg, 2019, 46(2):36-40.
- Liddle AD, Pandit H, Judge A, et al. Patient-reported outcomes after total and unicompartmental knee arthroplasty: a study of 14,076 matched patients from the National Joint Registry for England and Wales. Bone Joint J, 2015, 97-B(6):793-801.
- Kinov P, Stoyanov V, Hadziev D, et al. Results after unicondylar knee joint replacement. Bulg J Orthop Traumatol, 2017, 54(1):26-30.
- Georgiev GP, Maznov P, Belitova M, et al. Unicondylar knee arthroplasty and reconstruction of the anterior cruciate ligament. Bulg J Orthop Traumatol, 2019, 56(2):71-75.
- Kim TK, Mittal A, Meshram P, et al. Evidence-based surgical technique for medial unicompartmental knee arthroplasty. Knee Surg Relat Res, 2021,33(1):2.
- Berend KR, Lombardi AV Jr, Mallory TH, et al. Early failure of minimally invasive unicompartmental knee arthroplasty is associated with obesity. Clin Orthop Relat Res, 2005, 440:60-6.
- Kozinn SC, Scott R. Unicondylar knee arthroplasty. J Bone Joint Surg Am, 1989, 71(1):145-50.
- Kim KT, Lee S, Lee JS, et al. Long-term clinical results of unicompartmental knee arthroplasty in patients younger than 60 years of age: minimum 10-year follow-up. Knee Surg Relat Res, 2018, 30(1):28-33.
- Campi S, Tibrewal S, Cuthbert R, et al. Unicompartmental knee replacement - Current perspectives. J Clin Orthop Trauma, 2018, 9(1):17-23.
- Rajani AM, Shyam A. Modern perspectives on unicompartmental knee arthroplasty: an editorial review. J Orthop Case Rep, 2025,15(9):1-6.
- Bell SW, Anthony I, Jones B, et al. Improved accuracy of component positioning with robotic-assisted unicompartmental knee arthroplasty: data from a prospective, randomised controlled study. J Bone Joint Surg Am, 2016, 98(8):627-635.
- Batailler C, White N, Ranaldi FM, et al. Improved implant position and lower revision rate with robotic-assisted unicompartmental knee arthroplasty. Knee Surg Sports Traumatol Arthrosc, 2019, 27(4):1232-1240.
- Jeschke E, Gehrke T, Gunster C, et al. Five-year survival of 20,946 unicondylar knee replacements and patient risk factors for failure: an analysis of German Insurance Data. J Bone Joint Surg Am, 2016, 98(20): 1691-1698.
- Kandil A, Werner BC, Gwathmey WF, et al. Obesity, morbid obesity, and their related medical comorbidities are associated with increased complications and revision rates after unicompartmental knee arthroplasty. J Arthroplasty, 2015, 30(3):456-60.
- Pandit H, Jenkins C, Gill HS, et al. Minimally invasive Oxford phase 3 unicompartmental knee replacement: results of 1000 cases. J Bone Joint Surg Br, 2011,93(2):198-204.
- Vasso M, Antoniadis A, Helmy N. Update on unicompartmental knee arthroplasty: Current indications and failure modes. EFORT Open Rev, 2018, 3(8):442-448.
- Rajan S, Bretcanu O, Deehan DJ, et al. Comparative retrieval analysis of contemporary mobile and fixed unicompartmental knee bearing designs. J Mech Behav Biomed Mater, 2022, 127:105076.
- Liu P, Lu FF, Liu GJ, et al. Robotic-assisted unicompartmental knee arthroplasty: a review. Arthroplasty. 2021 May 2;3(1):15. doi: 10.1186/s42836-021-00071-x.
- Kayani B, Konan S, Pietrzak JRT, et al. The learning curve associated with robotic-arm assisted unicompartmental knee arthroplasty: a prospective cohort study. Bone Joint J, 2018, 100-B(8): 1033-1042.
- Lim MH, Tallay A, Bartlett J. Comparative study of the use of computer-assisted navigation system for axial correction in medial unicompartmental knee arthroplasty. Knee Surg Sports Traumatol Arthrosc, 2009,17(4):341-6.
- Zhang X, Han Y, Bai Q, et al. Clinical efficacy of unicompartmental knee arthroplasty on limb swelling, pain, and functional rehabilitation in knee osteoarthritis patients. J Orthop Surg Res, 2025, 20(1):616.
- Liddle AD, Judge A, Pandit H, et al. Adverse outcomes after total and unicompartmental knee replacement in 101,330 matched patients: a study of data from the National Joint Registry for England and Wales. Lancet, 2014, 384(9952): 1437-45.
- Liddle AD, Pandit H, Judge A, et al. Effect of surgical caseload on revision rate following total and unicompartmental knee replacement. J Bone Joint Surg Am, 2016, 98(1):1-8.
- Van der List JP, McDonald LS, Pearle AD. Systematic review of medial versus lateral survivorship in unicompartmental knee arthroplasty. Knee, 2015, 22(6):454-60.
- Hauer G, Sadoghi P, Bernhardt GA, et al. Greater activity, better range of motion, and higher quality of life following unicompartmental knee arthroplasty: a comparative case-control study. Arch Orthop Trauma Surg, 2020, 140(2):231-237.
- Naal FD, Fischer M, Preuss A, et al. Return to sports and recreational activity after unicompartmental knee arthroplasty. Am J Sports Med, 2007, 35(10):1688-95.
- Radhakrishnan GT, Magan A, Kayani B, et al. Return to sport after unicompartmental knee arthroplasty: a systematic review and meta-analysis. Orthop J Sports Med, 2022, 10(3):23259671221079285.
- Walker T, Streit J, Gotterbarm T, et al. Sports, physical activity and patient-reported outcomes after medial unicompartmental knee arthroplasty in young patients. J Arthroplasty, 2015, 30(11): 1911-G.
- Pasqualini I, Emara AK, Rullan PJ, et al. Return to sports and return to work after total knee arthroplasty: a systematic review and meta-analysis. JBJS Rev, 2023,11(7).
- Yang KY, Wang MC, Yeo SJ, et al. Minimally invasive unicondylar versus total condylar knee arthroplasty-early results of a matched-pair comparison. Singapore Med J, 2003, 44(11):559-62.
- Li Q, Zhai S, Mu Z, Zhang X. Comparison of early outcomes between unicompartmental and total knee arthroplasty in patients with anteromedial compartment knee osteoarthritis and class II obesity: a retrospective case analysis. Front Surg, 2025, 12:1616382.
- Suggs JF, Li G, Park SE, et al. Function of the anterior cruciate ligament after unicompartmental knee arthroplasty: an in vitro robotic study. J Arthroplasty, 2004, 19(2):224-9.
- Szymski D, Straub J, Walter N, et al. Revision of unicondylar knee arthroplasty: an analysis of failure rates and contributing factors. Knee Surg Relat Res, 2025, 37(1):25.
- Wu L, Zhang FI, Zhang Y, et al. Influence of patellofemoral joint degeneration on clinical outcomes and revision rates after medial unicompartmental knee arthroplasty: a systematic review and meta-analysis. J Orthop Surg Res, 2022, 17(1):1—9.
- Bonasia DE, Governale G, Spolaore S, et al. High tibial osteotomy. Curr Rev Musculoskelet Med, 2014, 7(4):292-301.
- Dettoni F, Bonasia DE, Castoldi F, et al. High tibial osteotomy versus unicompartmental knee arthroplasty for medial compartment arthrosis of the knee: a review of the literature. Iowa Orthop J, 2010, 30:131-40.
- Strickland LF-I, Rahman A, Jenkinson C, et al. Early recovery following total and unicompartmental knee arthroplasty assessed using novel patient-reported measures. J Arthroplasty, 2021,36(10):3413-3420.
- Ping FI, Wen J, Liu Y, et al. Unicompartmental knee arthroplasty is associated with lower pain levels but inferior range of motion, compared with high tibial osteotomy: a systematic overview of meta-analyses. J Orthop Surg Res, 2022, 17(1):425.
- Li P, Qiao Y, Zhou Y, et al. Comparative outcomes of revision total knee arthroplasty: a systematic review and meta-analysis of high tibial osteotomy vs. unicompartmental knee arthroplasty. BMC Musculoskelet Disord, 2025, 26(1):780.
- Kazarian GS, Lonner JFI, Maltenfort MG, et al. Cost-effectiveness of surgical and nonsurgical treatments for unicompartmental knee arthritis: a Markov model. J Bone Joint Surg Am, 2018, 100(19):1653-1660.
- Mohebbi S, Khani Y, Amiri A, et al. Economic evaluation of robotic-assisted versus manual unicompartmental knee arthroplasty: a systematic review of Markov models and clinical studies. J Orthop Surg Res, 2025, 20(1):623.
- Mohammad FIR, Judge A, Murray DW. The effect of age on the relative outcomes of cemented and cementless mobile- bearing unicompartmental knee arthroplasty, based on data from national databases. J Arthroplasty, 2023, 38(1):30-36. e1.
- lacono F, Raspugli GF, Akkawi I, et al. Unicompartmental knee arthroplasty in patients over 75 years: a definitive solution? Arch Orthop Trauma Surg, 2016,136(1):117-23.
- Leggieri F, Martin Cocilova FN, Civinini A, et al. Robotic- assisted joint line preserving unicompartmental knee arthroplasty positioning among octogenarians. J Pers Med, 2025, 15(8):362.
- Vasso M, Corona K, D’Apolito R, et al. Unicompartmental knee arthroplasty: modes of failure and conversion to total knee arthroplasty. Joints, 2017, 5(1):44-50.
- Pandit FI, Jenkins C, Gill FIS, et al. Unnecessary contraindications for mobile-bearing unicompartmental knee replacement. J Bone Joint Surg Br, 2011,93(5):622-8.
- Sun X, Liu P, Lu F, et al. Bearing dislocation of mobile bearing unicompartmental knee arthroplasty in East Asian countries: a systematic review with meta-analysis. J Orthop Surg Res, 2021, 16(1 ):28.
- Barbera JP, Xiao RC, Williams CS, et al. Treatment patterns and failure rates associated with prosthetic joint infection in unicompartmental knee arthroplasty: A systematic review. J Orthop, 2022, 34:288-294.
- Vasso M, Schiavone Panni A. Low-grade periprosthetic knee infection: diagnosis and management. J Orthop Traumatol, 2015, 16(1): 1-7.
- Tay ML, Young SW, Frampton CM, et al. The lifetime revision risk of unicompartmental knee arthroplasty. Bone Joint J, 2022, 104-B(6):672-679.
- Cobb J, Flenckel J, Gomes P, et al. Flands-on robotic uni-compartmental knee replacement: a prospective, randomised controlled study of the acrobot system. J Bone Joint Surg Br, 2006, 88(2): 188-97.
- Batailler C, Shatrov J, Sappey-Marinier E, et al. Artificial intelligence in knee arthroplasty: current concept of the available clinical applications. Arthroplasty, 2022, 4(1):17.
- Za P, Papalia GF, Cardile U, et al. Cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow-up of 4.2 years: A systematic review. J Exp Orthop, 2025,12(2):e70253.
- Abbas MJ, Market DC, Flallstrom BR, et al. The impact of surgeon volume on unicompartmental knee arthroplasty survivorship: a Michigan Arthroplasty Registry Collaborative Quality Initiative Database Analysis. J Arthroplasty, 2025, 40(1):15-21.
- Koch KA, Thapa M, Weishom J, et al. Cemented mobile- bearing medial unicompartmental knee arthroplasty provides long-term implant survival and sustained functional performance in young and active patients aged 60 or below. Knee Surg Sports Traumatol Arthrosc, 2025, 33(9):3324-3332.
Language: English
Page range: 90 - 99
Submitted on: Oct 13, 2025
Accepted on: Nov 20, 2025
Published on: Jun 16, 2026
Published by: Medical University - Sofia
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
Related subjects:
© 2026 D. Buonsante, G. P. Georgiev, published by Medical University - Sofia
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.