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Melolabial Advancement Flap for High-Risk BCC Near the Medial Eye Angle: Phototoxicity/ Photocarcinogenicity Triggered by Nitrosamines in the Polymedication as the Main Cause of Keratinocyte Cancer Development and Progression
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Tchernev G, Ivanov L. Mustarde rotation flap as adequate option for high-risk bcc near the lower eye lid: the additional intake of n-nitroso-folic-acid and n-nitroso-rivoroxaban as co- factors/triggers of the metabolic reprogramming of the future cancer cell. Georgian Med News. 2024 Jun;(351):131-137.
Tchernev G. Nitrosogenesis lessons from dermatologists- nitrosamines/ndsris contamination of the polimedication in polimorbid patients as the most powerful skin cancer inductor: double hatchet flap for scc of the scalp occurring during treatment with valsartan/hydrochlorothiazide and lercanidipine. Georgian Med News. 2023 Sep;(342):74-79.
Tchernev G. Nitrosogenesis of skin cancer: the nitrosamine contamination in the calcium channel blockers (amlodipine), beta blockers (bisoprolol), sartans (valsartan/losartan), ace inhibitors (perindopril/enalapril), tricyclic antidepressants (melitracen), ssris (paroxetine), snris (venlafaxine) and metformin: the most probable explanation for the rising skin cancer incidence. Georgian Med News. 2023 Jun;(339):24-32.
Tchernev G. The nitrosamine contamination in beta blockers (bisoprolol/metoprolol), ace inhibitors (lisinopril/perindopril), thiazides diuretics (hct), calcium channel blockers (amlodipine/felodipine), sartans (candesartan) and the subsequent skin cancer development and progression: apocalypse now. Georgian Med News. 2023 Apr;(337):138-145.
Tchernev G, Kordeva S, Lozev I. Metatypical bccs of the nose treated successfully via bilobed transposition flap: nitrosamines in aces (enalapril), arbs (losartan) as possible skin cancer key triggering factor. Georgian Med News. 2023 Feb;(335):22-25.
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Hou A, Li Y, Shadyab AH, et al. Photosensitizing antihypertensive medication and risk of skin cancer among postmenopausal women. J Dtsch Dermatol Ges. 2024 Feb;22(2):186-194. doi: 10.1111/ddg.15281.
Tchernev G. (N-nitroso) propafenone induced advanced nodular melanoma-first reported case in the world literature: the inextricable links between the photocarcinogenesis, drug related nitrosogenesis and pharmaco-oncogenesis. Georgian Med News. 2024 Feb;(347):34-37.
Tchernev G, Ivanov L, Broshtilova V. Multiple keratinocytic cancers after intake of antihypertensives (lisinopril/bisopro- lol/hct) and antiarrhytmics (propafenone): the important new links to the nitroso-contamination and the metabolic reprogramming of the future cancer cell. Georgian Med News. 2024 Jun;(351):65-71.
Tchernev G. Nitrosamine contamination within cardiac multimedication – sartans (valsartan), calcium channel blockers (amlodipine and nifedipine), and antiarrhythmics (propafenone) as a significant factor in the development and progression of multiple keratinocytic cancers: advancement rotation flap for keratoacanthoma of the upper lip and undermining surgery for bcc of the shoulder as an optimal dermatosurgical approach. Georgian Med News. 2023 Sep;(342):152-155.
Tchernev G, Naydekova N. Melanoma and dysplastic nevi development after ranitidine/rilmenidine/moxonidine, lercanidipine, rosuvastatin and verapamil/trandolapril – new data/case series. The potential role of nitrosamine/ndsris contamination in polymedication as substantial skin cancer triggering factor. Georgian Med News. 2023 Nov;(344):152-158.
Kordeva S, Ivanov L, Alexandrov A, et al. Keratinocyte cancers, dysplastic nevi and cutaneous melanoma development after intake of potentially nitrosamine/NDSRIs contaminated drugs: new data. Important links to photo-(nitroso-) carcinogenesis and pharmaco-oncogenesis. Medical Review (Med. pregled) 2024; 60(5): 62-72.
Tchernev G, Dimova D. Education from dermatologists: the simultaneously development of 16 keratinocytic cancers after use of metformin in combination with losartan/hydrochlorothiazide, metoprolol and nifedipine- important links to drug related (photo)-nitroso-carcinogenesis and oncopharmacogenesis. Georgian Med News. 2024 Feb;(347):136-141.
Tchernev G, Lozev I, Ivanov L. Morpheaform bcc of ala nasi: a successful dermatosurgical approach by transposition flap from the adjacent area. contamination of venlafaxine, bisoprolol and olanzapine with nitrosamines/ndsris: the most likely cause of skin cancer development and progression. Georgian Med News. 2023 Sep;(342):26-29.
Tchernev G, Kordeva S. Nitrosogenesis of skin (human) cancer- the hidden truth of a neverending story: nitrosamine contamination in olmesartan, valsartan and hct as main risk factor for the development of keratinocyte cancer. Georgian Med News. 2023 Apr;(337):63-67.