The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma

V. Racheva; I. Dekova; Z. Gorcheva; T. Semova; D. Dimitrov; E. Petkova

doi:10.2478/amb-2025-0006

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The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma

Acta Medica Bulgarica

Volume 52 (2025): Issue 1 (March 2025)

By: V. Racheva, I. Dekova, Z. Gorcheva, T. Semova, D. Dimitrov and E. Petkova

Open Access

|Mar 2025

Abstract

Ovarian carcinoma (OC) has the highest mortality among gynecological carcinomas in developed countries. Many authors have drawn attention to fibrinogen-to-pre-albumin (FPR) and albumin-to-fibrinogen (AFR) ratios and demonstrated that low AFR values and high FPR values correlate with an increased risk of mortality and recurrence of carcinoma and may be promising prognostic markers for malignant diseases. As emerging biomarkers, FPR and AFR have significant advantages due to their availability, costeffectiveness, and reliability.

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