High Colchicine Doses Are Really Silver Bullets Against COVID-19

V. Mitev

doi:10.2478/amb-2024-0085

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High Colchicine Doses Are Really Silver Bullets Against COVID-19

Acta Medica Bulgarica

Volume 51 (2024): Issue 4 (December 2024)

By: V. Mitev

Open Access

|Nov 2024

Abstract

The numerous attempts to prove a therapeutic effect of low-dose colchicine for the treatment of Coronavirus disease-2019 (COVID-19) have been discouraging. Increase of doses, however, leads to accumulation in leukocytes and inhibition of the cytokine storm thus preventing COVID-19 complications and hospitalizations. Hospital mortality drops up to 7-fold, while outpatients practically do not reach hospitalization.

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