Abstract
Breast cancer is a pathology associated with high morbidity and mortality among women of all nations worldwide. The low efficiency or total absence of national screening programs, the presence of comorbid mental illnesses or dementia, general lack of information and underestimation of the problem among patients are factors that often lead to late diagnosis of breast cancer and, as a result, to high mortality. The article presents 2 clinical cases of advanced breast cancer in women who underwent surgical treatment in our clinic, which demonstrate the necessity of emergency reconstruction of Bulgarian national screening program. A brief statistical analysis of morbidity, mortality and effectiveness of screening in different countries is conducted.