References
- Bivalacqua TJ, Usta MF, Champion HC, et al. Endothelial dysfunction in erectile dysfunction: role of the endothelium in erectile physiology and disease. J Androl, 2003; 24:17-37.
- Akomolafe S, Oboh G, Olasehinde T, et al. Modulatory effects of Aqueous extract from Tetracarpidium conophorum leaves on key enzymes linked to erectile dysfunction and oxidative stress-induced lipid peroxidation in penile and testicular tissues. Journal of Applied Pharmaceutical Science, 2017, 7 (01), 051-056.
- Hatzimouratidis K, Amar E, Eardley I, et al. Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. Eur. Urol., 2010, 57:804-814.
- Ayta IA, McKinlay JB, Krane RJ. The likely worldwide in-crease in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int 1999, 84:50-56.
- Oladiji F, Kayode OO, Parakoyi DB. Influence of socio-de-mographic characteristics on prevalence of erectile dysfunction in Nigeria. International journal of impotence research, 2013, 25(1), 18-23.
- Akintunde JK, Akintola TE, Aliu FH, et al. Naringin regulates erectile dysfunction by abolition of apoptosis and inflammation through NOS/cGMP/PKG Signalling pathway on exposure to Bisphenol-A in hypertensive rat model. Reproductive Toxicology, 2020, 95: 123-136.
- Kamenov Z, Fileva S, Kalinov K, Jannini EA. Evaluation of the Efficacy and Safety of Tribulus terrestris in Male Sexual Dysfunction -A Prospective, Randomized, Double-Blind, Placebo-ControlIed Clinical Trial. Maturitas 2017, http://dx.doi.org/10.1016/j.maturitas.2017.01.011
- Hirsch M, Donatucci C, Glina S, et al. Standards for clinical mandatory in male sexual dysfunction: erectile dysfunction and rapid ejaculation. J Sex Med, 2014,1 (1): 87-91.
- Wespes E, Amar E, Hatzichristou D, et al. EUA Guidelines on erectile dysfunction: an update. European Urology, 2006, 49:806-815.
- Ventimiglia E, Capogrosso P, Montorsi F, Salonia A. The safety of Phosphodiesterase type 5 Inhibitors for erectile dysfunction. Expert Opin Drug Saf 2016, 15:141-15.
- Bruzziches R, Francomano D, Gareri P, et al. An update on pharmacological treatment of erectile dysfunction with Phosphodiesterase type 5 Inhibitors. Expert Opin Pharmacother 2013, 14:1333-1344.
- Hardy L W, Malikayil A. The impact of structure-guided drug design on clinical agents. Curr. Drug Discov, 2003, 3, 15-20.
- Fatoki TH, Ibraheem O, Ogunyemi IO, et al. Network Analysis, Sequence and Structure Dynamics of Key Proteins of Coronavirus and Human Host, and Molecular Docking of Selected Phytochemicals of Nine Medicinal Plants. Journal of Biomolecular Structures and Dynamics, 2021, 39(16): 6195-6217.
- Masuku NP, Unuofin JO, Lebelo S. Promising role of medicinal plants in the regulation and management of male erectile dysfunction. Biomedicine & Pharmacotherapy, 2010,130, 110555.
- Ugbogu OC, Akukwe AR. The antimicrobial effect of oils from Pentaclethra macrophylla Bent, Chrysophyllum albidum G. Don and Persea gratissima Gaerth F on some local clinical bacteria isolates. African Journal of Biotechnology, 2010, 8(2), 285-287.
- Alinnor IJ, Oze R. Chemical evaluation of the nutritive value of Pentaclethra macrophylla Benth. (African Oil Bean) Seeds. Pak. J. Nutr. 2011, 10(4):355-359.
- Akindahunsi AA. Physicochemical studies on African oil bean (Pentaclethra macrophylla Benth.) seed. J Food Agric Environ, 2004, 2: 14-17.
- Nwankwo JO. Anticancer potentials of phytochemicals from some indigenous food and medicinal plants of West Africa. Advances in Cancer Prevention 2018;3(1):124.
- Sinda PVK, Ponou BK, Tsafack, et al. Ethnobotany, Pharmacology and Phytochemical Investigations of the Seeds of Pentaclethra macrophylla Benth (Mimosaceae). Advances in Biological Chemistry, 2021,11,126-141. https://doi.org/10.4236/abc.2021.113009
- Oboh G, Ademiluyi AO, Oyeleye SI, et al. Modulation of some markers of erectile dysfunction and malonaldehyde levels in isolated rat penile tissue with unripe and ripe plantain peels: identification of the constituents of the plants using HPLC. Pharmaceutical Biology, 2017, 55(1), 1920-1926.
- Sultana B, Anwar F, Ashraf M. Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules (Basel, Switzerland), 2009,14(6): 2167-2180.
- Harbourne JBC. Phytochemical Methods. Chapman and Hall, London: 279.
- Sofowora, A. 1995. Medicinal Plants and Traditional Medicines in Africa. ChichesterSohn, Willey and Sons, New York, 1973, 256.
- Trease GE, Evans WC. Pharmocology, 11th Edition. Bailliere Tindall Limited, London, 1978, 60-75.
- Edeoga HO, Okwu DE, Mbaebie BO. Phytochemical constituents of some Nigerian medicinal plants. African Journal of Biotechnology, 2005, 4:685-688.
- Waterman PG, Mole S. Analysis of Phenolic Plant Metabolites. Blackwell Scientific Publications. Methods in Ecology. Oxford. 1994.
- Meda A, Lamien CE, Romito Μ, et al. Determination of the total phenolic, flavonoid and proline contents in Burkina Faso honey, as well as their radical scavenging activity. Food Chemistry, 2005, 91, 571-577.
- Brand-Williams W, Cuvelier ME, Berset CLW. Use of a free radical method to evaluate antioxidant activity. LWT-Food Science and Technology, 1995, 28:25-30.
- Gangwar M, Gautam MK, Sharma AK, et al. Antioxidant capacity and radical scavenging effect of polyphenol rich Mallotusphilippenensis fruit extract on human erythrocytes: an in vitro study 2004.
- Daina A, Michielin O, Zoete V. SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules. Scientific Report, 2017, 7(1): 42717.
- Dozio E, Barassi A, Marazzi MG, et al. Plasma myeloperoxidase in patients with erectile dysfunction of arteriogenic- and non-arteriogenic origin_ association with markers of endothelial dysfunction. J Biol Regul Homeost Agents. 2013, 27(3):749-55.
- Stallmann-Jorgensen I, Webb RC. Emerging molecular targets for treatment of erectile dysfunction: vascular and regenerative therapies on the horizon. Current drug targets, 2015, 16(5), 427-441.
- Fatoki T, Chukwuejim S, Ibraheem O, et al. Harmine and 7,8-dihydroxyflavone synergistically suitable for amyotrophic lateral sclerosis management: An insilico study. Research Results in Pharmacology, 2022, 8(3):49-61.
- Morris GM, Huey R, Lindstrom W, et al. AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility. J. Comput Chem 2009, 30(16):2785-2791.
- Trott Ο, Olson AJ. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J Comput Chem. 2010, 31(2):455-461.
- Eberhardt J, Santos-Martins D, Tillack AF, Forli S. AutoDock Vina 1.2.0: New Docking Methods, Expanded Force Field, and Python Bindings, J. Chem. Inf. Model. 2021. https://doi.org/10.1021/acs.jcim.1c00203
- Tao A, Huang Y, Shinohara Y, et al. ezCADD: A Rapid 2D/3D Visualization-Enabled Web Modeling Environment for Democratizing Computer-Aided Drug Design. J. Chem. Inf. Model, 2019, 59, 18-24.
- Bowers KJ, Chow DE, Xu H, et al. Molecular dynamics – Scalable algorithms for molecular dynamics simulations on commodity clusters. In Proceedings of the 2006 ACM/IEEE Conference on Supercomputing – SC'06, Tampa, FL, USA, 2006.11-17.
- Schrödinger release 2023-1. Desmond molecular dynamics system, D.E. Shaw research, New York, NY, 2021. Maestro Desmond Interoperability Tools, Schrödinger, New York, NY, 2021.
- Fatoki T, Ajiboye BO, Aremu AO. In silico Evaluation of the Antioxidant, Anti-lnflammatory, and Dermatocosmetic Activities of Phytoconstituents in Licorice (Glycyrrhiza glabra L.). Cosmetics 2023, 10.
- Schrödinger (2019). What do ali the Prime MM-GBSA energy properties mean? http://www.schrodinger.com/kb/1875".
- Kiyohara H, Matsumoto T, Yamada H. Combination effects of herbs in a multi-herbal formula: Expression of Juzen-taiho-to's immuno-modulatory activity on the intestinal immune system. Evidence-based Complementary and Alternative Medicine 2004, 1(1): 83-91.
- Miyata Y, Matsuo T, Nakamura Y, et al. Pathological Significance of Macrophages in Erectile Dysfunction Including Peyronie's Disease. Biomedicines 2021, 9, 1658. https://doi.org/10.3390/biomedicines9111658
- Aladekoyi G, Orungbemi OO, Karim OA, Aladejimokun AO. Comparative studies of the nutritional and phytochemical constituents of African oil bean (Pentaclethra macrophylla benth) and African bean (Anthonotha macrophylla) for human consumption. Chem. Res. J., 2017, 2(3), 16-21.
- Okhale SE, Amuzie N, Imoisi C, Ibrahim JA. Phytochemical and HPLCUV-DAD chromatographic characterization of stem bark extracts of Pentaclethra macrophylla Benth used for management of diabetes mellitus in Nigeria. Ν Y Sci J 2022;15(3):41-49. https://10.0.29.113/marsnys150322.05".
- Okorie CC, Oparaocha ENT, Adewunmi CO. et al. Antinociceptive, Anti-Inflammatory and Cytotoxic Activities of Pentaclethra macrophylla Aqueous Extracts in Mice. African Journal of Traditional, Complementary and Alternative Medicines, 2006, 3,44-53.
- Oyinloye AM, Enujiugha VN. Antioxidant Properties of African Oil Bean (Pentaclethra macrophylla Benth) Seed Phenolics as Influenced by Extraction Solvents and Heat Treatments. Applied Tropical Agriculture, 2019, 24, 42-48.
- Saini G, Dalal V, Gupta DN, et al. A molecular docking and dynamic approach to screen inhibitors against ZnuA1 of Candidatus Liberibacter asiaticus. Mol. Simul. 2021, 47, 510-525.
- Fatoki TH Human adenovirus DNA Polymerase is evolutionarily and functionally associated with human telomerase reverse transcriptase based on in silico molecular characterization that implicate abacavir and zidovudine. Front. Bioinform. 2023, 3:1123307. doi: 10.3389/fbinf.2023.1123307
