Have a personal or library account? Click to login
Pathophysiology of Depression and Novel Sources of Phytochemicals for its Treatment – A Systematic Review Cover

Pathophysiology of Depression and Novel Sources of Phytochemicals for its Treatment – A Systematic Review

Open Access
|Nov 2020

References

  1. 1. Demyttenaere K, Bruffaerts R, Posada-Villa J, et al. Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys. JAMA. 2004; 291:2581-2590.10.1001/jama.291.21.258115173149
  2. 2. WHO, Fact Sheet – Mental Health 2019, Accessed 04.03.2019 at: http://www.euro.who.int/en/health-topics/noncommunicable-diseases/mental-health/data-and-resources/fact-sheet-mental-health-2019.
  3. 3. Hinkov H, Dimitrov P, Zarkov Z et al. National Representative Epidemiological Study Of Common Mental Disorders In Bulgaria Epibul 2, 2016-2017: Tool, Methodology, Process Evaluation. Soc Med. 2017; 1: 21-23.
  4. 4. Katz MM, Koslow SH, Berman N et al. A multi-vantaged approach to measurement of behavioral and affect states for clinical and psychobiological research. Psychol Rep. 1984; 55:619-671.10.2466/pr0.1984.55.2.6196514929
  5. 5. Katz MM, Maas JW. Psychopharmacology and the etiology of psychopathological states: are we looking in the right way? Neuropsychopharmacology. 1994; 10:139-144.
  6. 6. Mimura M. Comorbidity of Depression and Other Diseases. JMAJ 2001; 44(5): 225-229.
  7. 7. Kendler KS, Neale M, Kessler R et al. A twin study of recent life events and difficulties. Arch Gen Psychiatry. 1993; 50:789-796.10.1001/archpsyc.1993.018202200410058215803
  8. 8. Kendler KS, Gardner CO, Prescott CA. Toward a comprehensive developmental model for major depression in women. Am J Psychiatry. 2002; 159:1133-1145.10.1176/appi.ajp.159.7.113312091191
  9. 9. Kendler KS, Thornton LM, Gardner CO. Genetic risk, number of previous depressive episodes, and stressful life events in predicting onset of major depression. Am J Psychiatry. 2001; 158:582-156.10.1176/appi.ajp.158.4.58211282692
  10. 10. Goodwin GM. Depression and associated physical diseases and symptoms. Dialogues Clin Neurosci. 2006; 8(2):259-265.10.31887/DCNS.2006.8.2/mgoodwin
  11. 11. Schildkraut JJ. The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am J Psychiatry. 1965; 122(5):509-22.10.1176/ajp.122.5.5095319766
  12. 12. Bunney WE Jr, Davis JM. Norepinephrine in depressive reactions. A review. Arch Gen Psychiatry. 1965; 13(6):483-94.10.1001/archpsyc.1965.017300600010015320621
  13. 13. Hirschfeld RM. History and evolution of the monoamine hypothesis of depression. J Clin Psychiatry. 2000; 61 S6:4-6.
  14. 14. Delgado PL. Depression: the case for a monoamine deficiency. J Clin Psychiatry. 2000; 61 S6:7-11.
  15. 15. Muller JC, Pryor WW, Gibbons JE, Orgain ES. Depression and anxiety occurring during Rauwolfia therapy. J Am Med Assoc. 1955; 29; 159(9):836-9.10.1001/jama.1955.0296026000600213263127
  16. 16. Shore PA, Silver SL, Brodie BB.Interaction of reserpine, serotonin, and lysergic acid diethylamide in brain. Science. 1955; 122(3163):284-5.10.1126/science.122.3163.284.b
  17. 17. Shore PA, Pletscher A, Tomich EG et al. Role of brain serotonin in reserpine action. Ann N Y Acad Sci. 1957; 66(3):609-15; discussion, 615-7.
  18. 18. Weiner N, Cloutier G, Bjur R, Pfeffer RI. Modification of norepinephrine synthesis in intact tissue by drugs and during short-term adrenergic nerve stimulation. Pharmacol Rev. 1972; 24(2): 203-221.
  19. 19. Mann JJ. Loss of antidepressant effect with long-term monoamine oxidase inhibitor treatment without loss of monoamine oxidase inhibition. J Clin Psychopharmacol. 1983; 3:363-366.10.1097/00004714-198312000-00007
  20. 20. Fava M, Rappe SM, Pava JA, et al. Relapse in patients on long-term fluoxetine treatment respond to increased fluoxetine dose. J. Clin Psychiatry. 1995; 56:52-55.
  21. 21. Sharma V. Loss of response to antidepressants and subsequent refractoriness: diagnostic issues in a retrospective case series. J Affect Disord. 2001; 64:99-106.10.1016/S0165-0327(00)00212-3
  22. 22. Drevets WC, Price JL, Simpson JR Jr et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature. 1997; 386:824-827.10.1038/386824a0
  23. 23. Russo SJ, Nestler EJ. The brain reward circuitry in mood disorders. Nat Rev Neurosci. 2013; 14:609-625.10.1038/nrn3381
  24. 24. Rajkowska G, Miguel-Hidalgo JJ, Wei J et al. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biol Psychiatry. 1999; 45:1085-1098.10.1016/S0006-3223(99)00041-4
  25. 25. Kang HJ, Kim JM, Lee JY et al. BDNF promoter methylation and suicidal behavior in depressive patients. J Affect Disord. 2013; 151:679-685.10.1016/j.jad.2013.08.00123992681
  26. 26. Duric V, Banasr M, Stockmeier CA et al. Altered expression of synapse and glutamate related genes in postmortem hippocampus of depressed subjects. Int J Neuropsychopharmacol. 2013; 16:69-82.10.1017/S1461145712000016341464722339950
  27. 27. 2Morales-Medina JC, Juarez I, Venancio-Garcia E et al. Impaired structural hippocampal plasticity is associated with emotional and memory deficits in the olfactory bulbectomized rat. Neuroscience. 2013; 236:233-243.10.1016/j.neuroscience.2013.01.03723357118
  28. 28. Willner P, Scheel-Krüger J. The neurobiology of depression and antidepressant action. Neuroscience and Biobehavioral Reviews 2013; 37: 2331-2371.10.1016/j.neubiorev.2012.12.00723261405
  29. 29. Bremner JD, Randall P, Scott TM et al. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am J Psychiatry. 1995; 152: 973-981.10.1176/ajp.152.7.97332337677793467
  30. 30. Lee T, Jarome T, Li SJ, Kim JJ, Helmstetter FJ. Chronic stress selectively reduces hippocampal volume in rats: a longitudinal magnetic resonance imaging study. Neuroreport. 2009; 20: 1554-1558.10.1097/WNR.0b013e328332bb09
  31. 31. Conrad CD, LeDoux JE, Magarinos AM, McEwen BS. Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behav Neurosci. 1999; 113: 902-913.10.1037/0735-7044.113.5.902
  32. 32. Schoenfeld TJ, Gould E. Stress, stress hormones, and adult neurogenesis. Exp Neurol. 2012; 233:12-21.10.1016/j.expneurol.2011.01.008
  33. 33. Grønli J, Bramham C, Murison R et al. Chronic mild stress inhibits BDNF protein expression and CREB activation in thedentate gyrus but not in the hippocampus proper. Pharm Bio Behav. 2006; 85(4):842-9.10.1016/j.pbb.2006.11.021
  34. 34. Duman RS, Heninger GR, Nestler EJ. A molecular and cellular theory of depression. Arch. Gen. Psychiatry. 1997; 54(7):597-606.
  35. 35. Duman RS, Monteggia LM. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry. 2006; 59(12):1116-1127.
  36. 36. Björkholm C, Monteggia LM. BDNF – a key transducer of antidepressant effects. Neuropharmacology. 2016; 102:72–79. doi:10.1016/j.neuropharm.2015.10.03410.1016/j.neuropharm.2015.10.034
  37. 37. Levinson, D. The genetics of depression: a review. Biological Psychiatry. 2006; 60 (2): 84-92.10.1016/j.biopsych.2005.08.024
  38. 38. Maurice, DH, Ke, H, Ahmad, F et al. Advances in targeting cyclic nucleotide phosphodiesterases. Nat. Rev. Drug Discov. 2014; 13, 290-314.
  39. 39. Rose, GM, Hopper, A, De Vivo, M, Tehim, A. Phosphodiesterase inhibitors for cognitive enhancement. Curr. Pharm. Des. 2005; 11:3329-3334.
  40. 40. García-Osta, A, Cuadrado-Tejedor, M, Garcia-Barroso, C et al. Phosphodiesterases as therapeutic targets for Alzheimer’s disease. ACS Chem. Neurosci. 2012; 3:832-844.
  41. 41. Pearse, DD, Hughes, ZA. PDE4B as a microglia target to reduce neuroinflammation. Glia. 2016; 64:1698-1709.10.1002/glia.22986
  42. 42. Zou, ZQ, Chen, JJ, Feng, HF et al. Novel phosphodiesterase 4 inhibitor FCPR03 alleviates lipopolysaccharide-induced neuroinflammation by regulation of the cAMP/PKA/CREB signaling pathway and NF-kappaB Inhibition. J. Pharmacol. Exp. Ther. 2017; 362, 67-77.
  43. 43. Yu, H, Zou, Z, Zhang, X et al. Inhibition of phosphodiesterase 4 by FCPR03 alleviates lipopolysaccharide-induced depressive-like behaviors in mice: involvement of p38 and JNK signaling pathways. Int. J. Mol. Sci. 2018; 19: E513.10.3390/ijms19020513
  44. 44. Kuo DC, Tran M, Shah AA, et al. Depression and the suicidal patient. Emerg Med Clin North Am 2015; 33:765-78.10.1016/j.emc.2015.07.005
  45. 45. Riede, HL. Fourth-generation fluoroquinolones in tuberculosis. Lancet. 2009; 373 (9670): 1148-1149.10.1016/S0140-6736(09)60559-6
  46. 46. Fox H, Gibas T. Synthetic tuberculostats. V. Alkylidene derivatives of isonicotinyhydrazineJ. Org. Chem. 1953; 18(8): 983-989
  47. 47. Loomer, HP, Saunders, JC, Kline, NS. A clinical and pharmacodynamic evaluation of iproniazid as a psychic energizer. Psychiatric Research Reports. 1957; 8:129-141.
  48. 48. Chockalingam R, Gott BM, Conway CR. Tricyclic Antidepressants and Monoamine Oxidase Inhibitors: Are They Too Old for a New Look? Handbook of Experimental Pharmacology. 2019;250:37-48.
  49. 49. Walker FG. A critical review of the mechanism of action for the selective serotonin reuptake inhibitors: Do these drugs possess anti-inflammatory properties and how relevant is this in the treatment of depression? Neuropharmacology, 2013; 67: 304-317.
  50. 50. Lu Y, Mak KK, Van Bever HP, et al Prevalence of anxiety and depressive symptoms in adolescents with asthma: a meta-analysis and meta-regression. Pediatr Allergy Immunol. 2012; 23:707-715.10.1111/pai.1200022957535
  51. 51. Lim VZ, Ho RC, Tee SI, et al. Anxiety and depression in patients with atopic dermatitis in a Southeast Asian tertiary dermatological center. Ann Acad Med Singapore 2016.10.47102/annals-acadmedsg.V45N10p451
  52. 52. Zhang MW, Ho RC, Cheung MW, et al. Prevalence of depressive symptoms in patients with chronic obstructive pulmonary disease: a systematic review, meta-analysis and meta-regression. Gen Hosp Psychiatry 2011; 33:217-23.10.1016/j.genhosppsych.2011.03.00921601717
  53. 53. Mak A, Tang CS, Chan MF, et al. Damage accrual, cumulative glucocorticoid dose and depression predict anxiety in patients with systemic lupus erythematosus. Clin Rheumatol 2011.10.1007/s10067-010-1651-821221690
  54. 54. Ho RC, Fu EH, Chua AN, et al. Clinical and psychosocial factors associated with depression and anxiety in Singaporean patients with rheumatoid arthritis. Int J Rheum Dis 2011; 14:37-47.10.1111/j.1756-185X.2010.01591.x21303480
  55. 55. Mak KK, Kong WY, Mak A, et al. Polymorphisms of the serotonin transporter gene and post-stroke depression: a meta-analysis. J Neurol Neurosurg Psychiatry 2013.10.1136/jnnp-2012-30379123236014
  56. 56. Liddell, Henry and Robert Scott (1980). A Greek-English Lexicon (Abridged Edition). United Kingdom: Oxford University Press. ISBN 0-19-910207-4.
  57. 57. Kessler, RC, Soukup, J, Davis, RB et al. The use of complementary and alternative therapies to treat anxiety and depression in the United States. Am. J. Psychiatry. 2001; 158:289-294.
  58. 58. Harvey, AL, Young, LC, Viljoen, AM, Gericke, NP. Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids. Journal of Ethnopharmacology. 2011; 137(3):1124-1129.10.1016/j.jep.2011.07.03521798331
  59. 59. Hanks, GR. (ed.). Narcissus and daffodil: The genus Narcissus. CRC Press, Boca Raton, FL, 2003.10.1201/9780203219355
  60. 60. Heinrich, M, Barnes, J, Gibbons, S, Williamson, E. Fundamentals of Pharmacognosy and Phytotherapy. Churchill Livingstone, London, 2004.
  61. 61. Kumar, V. Potential medicinal plants for CNS disorders: an overview. Phytother. Res. 2006; 20(12):1023-1035.
  62. 62. Spinella, M. The Psychopharmacology of Herbal Medicine: Plant Drugs That Alter Mind, Brain and Behavior (Paperback). MIT Press, Cambridge, 2001.
  63. 63. Rahimi, R, Nikfar, S, Abdollahi, M. Efficacy and tolerability of Hypericum perforatumin major depressive disorder in comparison with selective serotonin reuptake inhibitors: a meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry. 2009; 33:118-127.10.1016/j.pnpbp.2008.10.01819028540
  64. 64. Buket B, Ahmet E, Gulen K et al. Somer. Alkaloid Profiling of Galan-thus woronowii Losinsk. by GC-MS and evaluation of its biological activity. Marmara Pharmaceutical Journal. 2017; 21 (4):915-920.10.12991/mpj.2017.12
  65. 65. Berkov, S, Osorio E, Viladomat F, Bastida J. Chapter Two – Chemodiversity, chemotaxonomy and chemoecology of Amaryllidaceae alkaloids. The Alkaloids: Chemistry and Biology. 2020; 83: 113-185.
  66. 66. Artyushenko, ZT. Amaryllidaceae of USSR, morphology, taxonomy and use. Nauka, Leningrad, Russia, 1970.
  67. 67. Khamidkhodzhaev, SA. Biology, resources and introduction of medicinal plants of Ungernia Bunge and Ficus L. in Middle Asia. Main Botanical Garden, Moscow, Russia, Dr. Sci. Diss. Abstr, 1984.
  68. 68. Pigni, NB, Berkov, S, Elamrani, A, et al. Two New Alkaloids from Narcissus serotinus L.. Molecules, 2010; 15: 7083-7089.10.3390/molecules15107083625924920948496
  69. 69. Birks, J Birks, Jacqueline S. Cholinesterase inhibitors for Alzheimer’s disease. The Cochrane Database of Systematic Reviews. 2006; 1: CD005593.10.1002/14651858.CD005593
  70. 70. Bodendorf, K, Krieger, W. Alkaloids of Mesembryanthemum tortuosum. Arch. Pharm. 1957; 290:441.
  71. 71. Smith, MT, Crouch, NR, Gericke, N, Hirst, M. Psychoactive Constituents of the Genus Sceletium N.E.Br. and other Mesembryanthemaceae: A Review. Journal of Ethnopharmacology. 1996; 50(3):119-130.10.1016/0378-8741(95)01342-3
  72. 72. Gericke, N, Van Wyk, B. In African Natural Health CC(Ed.), Pharmaceutical compositions containing mesembrine, 2001.
  73. 73. Harvey, A. In Gericke N. (Ed.), Personal communication to Nigel Gericke, 2008.
  74. 74. Napoletano M, Norcini G, Pellacini F et al. Phthalazine PDE4 inhibitors. Part 2: the synthesis and biological evaluation of 6-methoxy-1,4-disubstituted derivatives. Bioorg Med Chem Lett. 2001;11(1):33-7.10.1016/S0960-894X(00)00587-4
  75. 75. Houslay, M, Schafer, P, Zhang, K. Keynote review: Phosphodiesterase-4 as a therapeutic target. Drug Discovery Today. 2005; 15:11503.10.1016/S1359-6446(05)03622-6
  76. 76. Fujimaki, K, Morinobu, S, Duman, R. Administration of a cAMP Phosphodiesterase 4 Inhibitor Enhances Antidepressant-Induction of BDNF mRNA in Rat Hippocampus. Neuropsychopharmacol, 2000; 22: 42-51.10.1016/S0893-133X(99)00084-6
DOI: https://doi.org/10.2478/amb-2020-0049 | Journal eISSN: 2719-5384 | Journal ISSN: 0324-1750
Language: English
Page range: 69 - 74
Submitted on: Apr 25, 2020
Accepted on: Jun 7, 2020
Published on: Nov 24, 2020
Published by: Sofia Medical University
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 D. Bakalov, R. Hadjiolova, D. Pechlivanova, published by Sofia Medical University
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.