Sebaceous Carcinoma – Unexpected Tumor of the Nasal Ala Dorsum

Vlaykov, At.; Stefanov, At.; Velev, V.; Gulubova, M.; Ananiev, J.

doi:10.2478/amb-2019-0032

Abstract

Today, the extraocular variant of sebaceous carcinoma is still being poorly recognized. This type of carcinoma is rarely diagnosed correctly, which, together with its aggressive behavior, contributes to its poor prognosis. We present a case of an 84-year-old man with a history of left nasal ala tumor formation, diagnosed morphologically and immunohistochemically as sebaceous carcinoma.

References

1. Nelson BR, Hamlet KR, Gillard M et al. Sebaceous carcinoma. J Am Acad Dermatol. 1995;33:1-15.10.1016/0190-9622(95)90001-2
Search in Google Scholar Back to article
2. Bongu A, Lee ES, Peters SR, Chokshi RJ. Locally aggressive and multicentric recurrent extraocular sebaceous carcinoma: case report and literature review. Eplasty. 2013;21;13:e44.
Search in Google Scholar Back to article
3. Cieza-Díaz DE, Cano-Martínez N, Barchino-Ortiz L, Longo-Imedio I. Extraocular sebaceous carcinoma: a report of 2 cases. Actas Dermosifiliogr. 2012;103(10):919-22.10.1016/j.ad.2011.05.02222265011
Search in Google Scholar Back to article
4. Shalin SC, Lyle S, Calonje E, Lazar AJ. Sebaceous neoplasia and the Muir-Torre syndrome: important connections with clinical implications. Histopathology. 2010;56(1):133-47.10.1111/j.1365-2559.2009.03454.x
Search in Google Scholar Back to article
5. Rao NA, Hidayat AA, McLean IW, Zimmerman LE. Sebaceous carcinomas of the ocular adnexa: A clinicopathologic study of 104 cases, with five-year follow-up data. Hum Pathol. 1982;13(2):113-22.10.1016/S0046-8177(82)80115-9
Search in Google Scholar Back to article
6. Dummer R, Pittelkow MR, Iwatsuki K et al. Skin Cancer – A World-Wide Perspective. Springer 2011. 153-154.10.1007/978-3-642-05072-5
Search in Google Scholar Back to article
7. Shields JA, Shields CL. Eyelid, Conjunctival and Orbital Tumours: atlas and textbook 2nd ed. Lippincott W&W 2008. 50-52.
Search in Google Scholar Back to article
8. Cieza-Díaz DE, Cano-Martínez N, Barchino-Ortiz L, Longo-Imedio I. Extraocular sebaceous carcinoma: a report of 2 cases. Actas Dermosifiliogr. 2012;103(10):919-22.10.1016/j.ad.2011.05.022
Search in Google Scholar Back to article
9. Nijhawan N, Ross MI, Diba R et al. Experience with sentinel lymph node biopsy for eyelid and conjunctival malignancies at a cancer center. Ophthal Plast Reconstr Surg 2004; 20: 291-295.10.1097/01.IOP.0000131733.36054.3615266143
Search in Google Scholar Back to article
10. Osada S, Ueno T, Inai S et al. Sebaceous carcinoma of the nose with a regional metastasis following false-negative sentinel lymph node biopsy. Acta Derm Venereol. 2011;91(3): 367-8.10.2340/00015555-104721461553
Search in Google Scholar Back to article
11. Alawi F, Siddiqui A. Sebaceous carcinoma of the oral mucosa: Case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005; 99: 79.10.1016/j.tripleo.2004.05.00715599352
Search in Google Scholar Back to article
12. Hornblass A, Lauer SA. Sebaceous carcinoma of the eyelids. Ophthalmology 2004; 111: 2149.10.1016/j.ophtha.2004.10.01915582066
Search in Google Scholar Back to article
13. Wick M, Swanson PE. Cutaneous adnexal tumors: a guide to pathologic diagnosis. Am Soc Clin Pathol. 1991;113:374-382.
Search in Google Scholar Back to article
14. Phan K, Loya A. Mohs micrographic surgery versus wide local excision for sebaceous adenocarcinoma of the eyelid: Analysis of a national database. J Plast Reconstr Aesthet Surg. 2019 Mar 2. pii: S1748-6815(19)30074-9.
Search in Google Scholar Back to article

Sebaceous Carcinoma – Unexpected Tumor of the Nasal Ala Dorsum

Abstract

Paradigm

My account