References
- Baranov A, Gale RP, Guskova A et al (1989) Bone marrow transplantation after the Chernobyl nuclear accident. N Engl J Med 321:205–212. https://doi.org/10.1056/NEJM198907273210401
- Basic-Jukić N, Labar B (2003) [Immunosuppressive drugs in the prevention and treatment of GVHD after allogeneic bone marrow transplantation] (in Croatian). Acta Med Croatica 57:131–139.
- Billingham RE (1966) The biology of graft-versus-host reactions. Harvey Lect 62:21–78.
- Coeytaux K, Bey E, Christensen D et al (2015) Reported radiation overexposure accidents worldwide, 1980–2013: A systematic review. PLoS One 10:e0118709. https://doi.org/10.1371/journal.pone.0118709
- Cwykiel J, Jundzill A, Klimczak A et al (2021a) Donor recipient chimeric cells induce chimerism and extend survival of vascularized composite allografts. Arch Immunol Ther Exp 69:13. https://doi.org/10.1007/s00005-021-00614-9
- Cwykiel J, Klimczak A, Jundzill A et al (2011) Therapeutic potential of ex-vivo fused chimeric cells in prolonging vascularized skin allograft survival. Plast Reconstr Surg 127:26. https://doi.org/10.1097/01.prs.0000396723.40767.22
- Cwykiel J, Kwiecień GJ (2015) Cellular therapies in post-radiation syndrome. In: Siemionow M (ed) Plastic and reconstructive surgery: Experimental models and research designs. Springer, London, Heidelberg, New York, pp 629–636.
- Cwykiel J, Madajka-Niemeyer M, Siemionow M (2021b) Development of donor recipient chimeric cells of bone marrow origin as a novel approach for tolerance induction in transplantation. Stem Cell Investig 8:8. https://doi.org/10.21037/sci-2020-044
- Cwykiel J, Siemionow M (2014) Cellular therapy models: Ex vivo chimera model by cell fusion. Plast Reconstr Surg 29:593–603. https://doi.org/10.1007/978-1-4471-6335-0_72
- Cwykiel J, Siemionow M (2015) In vivo chimera model: Creation of primary and secondary chimera. In: Siemionow M (ed) Plastic and reconstructive surgery: Experimental models and research designs. Springer, London, Heidelberg, New York, pp 581–591.
- Ghimire S, Weber D, Mavin E et al (2017) Pathophysiology of GvHD and other HSCT-related major complications. Front Immunol 8:79. https://doi.org/10.3389/fimmu.2017.00079
- Gourmelon P, Benderitter M, Bertho JM et al (2010) European consensus on the medical management of acute radiation syndrome and analysis of the radiation accidents in Belgium and Senegal. Health Phys 98:825–832. https://doi.org/10.1097/HP.0b013e3181ce64d4
- Hagby M, Goldberg A, Becker S et al (2009) Health implications of radiological terrorism: Perspectives from Israel. J Emerg Trauma Shock 2:117–123. https://doi.org/10.4103/0974-2700.50747
- Heslet L, Bay C, Nepper-Christensen S (2012) Acute radiation syndrome (ARS) – Treatment of the reduced host defense. Int J Gen Med 5:105–115. https://doi.org/10.2147/IJGM.S22177
- Hirama T, Tanosaki S, Kandatsu S et al (2003) Initial medical management of patients severely irradiated in the Tokai-mura accident. Br J Radiol 76:246–253. https://doi.org/10.1259/bjr/82373369
- Hivelin M, Klimczak A, Cwykiel J et al (2016) Immunomodulatory effects of different cellular therapies of bone marrow origin on chimerism induction and maintenance across MHC barriers in a face allotransplantation model. Arch Immunol Ther Exp 64: 299–310. https://doi.org/10.1007/s00005-015-0380-8
- Hollingsworth BA, Aldrich JT, Case CM Jr et al (2023) Immune dysfunction from radiation exposure. Radiat Res 200:396–416. https://doi.org/10.1667/RADE-22-00004.1
- Jackson IL, Gurung G, Ayompe E et al (2021) Characterization of the hemorrhagic syndrome in the New Zealand white rabbit model following total body irradiation. Int J Radiat Biol 97:S32–S44. https://doi.org/10.1080/09553002.2020.1820601
- Klimczak A, Unal S, Jankowska A et al (2007) Donor-origin cell engraftment after intraosseous or intravenous bone marrow transplantation in a rat model. Bone Marrow Transplant 40: 373–380. https://doi.org/10.1038/sj.bmt.1705743
- Koch A, Gulani J, King G et al (2016) Establishment of early endpoints in mouse total-body irradiation model. PLoS One 11:e0161079. https://doi.org/10.1371/journal.pone.0161079
- Lim M, Wang W, Liang L et al (2018) Intravenous injection of allogeneic umbilical cord-derived multipotent mesenchymal stromal cells reduces the infarct area and ameliorates cardiac function in a porcine model of acute myocardial infarction. Stem Cell Res Ther 9:129. https://doi.org/10.1186/s13287-018-0888-z
- López M, Martín M (2011) Medical management of the acute radiation syndrome. Rep Pract Oncol Radiother 16:138–146. https://doi.org/10.1016/j.rpor.2011.05.001
- Macià I Garau M, Lucas Calduch A, López EC (2011) Radiobiology of the acute radiation syndrome. Rep Pract Oncol Radiother 16:123–130. https://doi.org/10.1016/j.rpor.2011.06.001
- Mettler FA Jr., Gus’kova AK, Gusev I (2007) Health effects in those with acute radiation sickness from the Chernobyl accident. Health Phys 93:462–469. https://doi.org/10.1097/01.HP.0000278843.27969.74
- Moris D, Cendales LC (2021) Sensitization and desensitization in vascularized composite allotransplantation. Front Immunol 12:682180. https://doi.org/10.3389/fimmu.2021.682180
- Ossetrova NI, Ney PH, Condliffe DP et al (2016) Acute radiation syndrome severity score system in mouse total-body irradiation model. Health Phys 111:134–144. https://doi.org/10.1097/HP.0000000000000499
- Ostheim P, Don Mallawaratchy A, Müller T et al (2021) Acute radiation syndrome-related gene expression in irradiated peripheral blood cell populations. Int J Radiat Biol 97:474–484. https://doi.org/10.1080/09553002.2021.1876953
- Schroeder MA, DiPersio JF (2011) Mouse models of graft-versus-host disease: Advances and limitations. Dis Model Mech 4: 318–333. https://doi.org/10.1242/dmm.006668
- Shulman HM, Cardona DM, Greenson JK et al (2015) NIH Consensus development project on criteria for clinical trials in chronic graft-versus-host disease: II. The 2014 Pathology Working Group Report. Biol Blood Marrow Transplant 21:589–603. https://doi.org/10.1016/j.bbmt.2014.12.031
- Siemionow M, Cwykiel J, Chambily L, Gacek S, Brodowska S. Novel Human Umbilical Di-Chimeric (HUDC) cell therapy for transplantation without life-long immunosuppression. Stem Cell Investig. 2023 Aug 14;10:16; https://doi.org/10.21037/sci-2023-02
- Siemionow M, Cwykiel J, Marchese E et al (2018b) A novel human myoblast chimeric cells therapy for restoration of muscle function. Transplantation 102:S355. https://doi.org/10.1097/01.tp.0000543097.21030.13
- Siemionow M, Cwykiel J, Madajka M (2015) Bone marrow-derived ex vivo created hematopoietic chimeric cells to support engraftment and maintain long-term graft survival in reconstructive transplantation. In: Brandacher G (ed) The science of reconstructive transplantation. Stem Cell Biology and Regenerative Medicine. Humana Press, New York, NY, pp 227–254. https://doi.org/10.1007/978-1-4939-2071-6_16
- Siemionow M, Cwykiel J, Heydemann A et al (2018a) Creation of dystrophin expressing chimeric cells of myoblast origin as a novel stem cell based therapy for Duchenne muscular dystrophy. Stem Cell Rev Rep 14:189–199. https://doi.org/10.1007/s12015-017-9792-7
- Siemionow MZ, Klimczak A, Unal S (2005a) Different routes of donor-derived hematopoietic stem cell transplantation for donor-specific chimerism induction across MHC barrier. Transplant Proc 37:62–64. https://doi.org/10.1016/j.transproceed.2004.12.216
- Siemionow M, Zielinski M, Ozmen S et al (2005b) Intraosseus transplantation of donor-derived hematopoietic stem and progenitor cells induces donor-specific chimerism and extends composite tissue allograft survival. Transplant Proc 37:2303–2308. https://doi.org/10.1016/j.transproceed.2005.03.127
- Srinagesh HK, Levine JE, Ferrara JLM (2019) Biomarkers in acute graft-versus-host disease: New insights. Ther Adv Hematol 10:2040620719891358. https://doi.org/10.1177/2040620719891358
- Weisdorf D, Chao N, Waselenko JK et al (2006) Acute radiation injury: Contingency planning for triage, supportive care, and transplantation. Biol Blood Marrow Transplant 12:672–682. https://doi.org/10.1016/j.bbmt.2006.02.006