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Oestrogenic and androgenic activity of oxybenzone and methylparaben in vitro Cover

Oestrogenic and androgenic activity of oxybenzone and methylparaben in vitro

Archives of Industrial Hygiene and Toxicology
Volume 76 (2025): Issue 1 (March 2025)
By: Nikolina Peranić,  Lucija Božičević and  Ivana Vinković Vrček  
Open Access
|Mar 2025

Figures & Tables

Figure 1

Viability of HeLa-9903 cells treated with: a) oxybenzone and b) methylparaben. The results are given as mean % of live cells vs negative control (untreated cells) and denote means with standard deviations of six replicates from two individual experiments. Cells treated with 10 % (v/v) DMSO served as positive control
Viability of HeLa-9903 cells treated with: a) oxybenzone and b) methylparaben. The results are given as mean % of live cells vs negative control (untreated cells) and denote means with standard deviations of six replicates from two individual experiments. Cells treated with 10 % (v/v) DMSO served as positive control

Figure 2

Viability of AR-EcoScreen GR KO M1 cells treated with: a) oxybenzone and b) methylparaben. The results are given as mean % of live cells vs negative control (untreated cells) and denote means with standard deviations of six replicates from two individual experiments. Cells treated with 10 % (v/v) DMSO served as positive control
Viability of AR-EcoScreen GR KO M1 cells treated with: a) oxybenzone and b) methylparaben. The results are given as mean % of live cells vs negative control (untreated cells) and denote means with standard deviations of six replicates from two individual experiments. Cells treated with 10 % (v/v) DMSO served as positive control

Figure 3

Androgenic activity of a) oxybenzone and b) methylparaben in the AR-EcoScreen GR KO M1 cell line. The results are given as mean % of inhibition vs positive control (500 pmol/L dihydrotestosterone) and denote means with standard deviations (error bars) of six replicates from two individual experiments. Standard deviations are given as error bars
Androgenic activity of a) oxybenzone and b) methylparaben in the AR-EcoScreen GR KO M1 cell line. The results are given as mean % of inhibition vs positive control (500 pmol/L dihydrotestosterone) and denote means with standard deviations (error bars) of six replicates from two individual experiments. Standard deviations are given as error bars

Figure 4

Anti-androgenic activity of a) oxybenzone and b) methylparaben in the AR-EcoScreen GR KO M1 cell line. The results are given as mean % of inhibition vs positive control (500 pmol/L dihydrotestosterone) and denote means with standard deviations (error bars) of six replicates from two individual experiments. Standard deviations are given as error bars
Anti-androgenic activity of a) oxybenzone and b) methylparaben in the AR-EcoScreen GR KO M1 cell line. The results are given as mean % of inhibition vs positive control (500 pmol/L dihydrotestosterone) and denote means with standard deviations (error bars) of six replicates from two individual experiments. Standard deviations are given as error bars

Figure 5

Estrogenic activity of a) oxybenzone and b) methylparaben in HeLa-9903 cells. The results are given as mean % of inhibition vs positive control (1 nmol/L 17 β-oestradiol) and denote means with standard deviations (error bars) of six replicates from two individual experiments. Standard deviations are given as error bars
Estrogenic activity of a) oxybenzone and b) methylparaben in HeLa-9903 cells. The results are given as mean % of inhibition vs positive control (1 nmol/L 17 β-oestradiol) and denote means with standard deviations (error bars) of six replicates from two individual experiments. Standard deviations are given as error bars
DOI: https://doi.org/10.2478/aiht-2025-76-3964 | Journal eISSN: 1848-6312 | Journal ISSN: 0004-1254
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Language: English, Croatian, Slovenian
Page range: 53 - 59
Submitted on: Feb 1, 2025
|
Accepted on: Mar 1, 2025
|
Published on: Mar 31, 2025
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
agonist,
antagonist,
AR-EcoScreen GR KO M1,
endocrine disruption,
HeLa-9903,
hormone receptors,
personal care products
Related subjects:
Medicine,
Basic medical science,
Basic medical science, other

© 2025 Nikolina Peranić, Lucija Božičević, Ivana Vinković Vrček, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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