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Oestrogenic and androgenic activity of oxybenzone and methylparaben in vitro Cover

Oestrogenic and androgenic activity of oxybenzone and methylparaben in vitro

Archives of Industrial Hygiene and Toxicology
Volume 76 (2025): Issue 1 (March 2025)
By: Nikolina Peranić,  Lucija Božičević and  Ivana Vinković Vrček  
Open Access
|Mar 2025
Figures & tables

Figures & Tables

Figure 1

Viability of HeLa-9903 cells treated with: a) oxybenzone and b) methylparaben. The results are given as mean % of live cells vs negative control (untreated cells) and denote means with standard deviations of six replicates from two individual experiments. Cells treated with 10 % (v/v) DMSO served as positive control

Figure 2

Viability of AR-EcoScreen GR KO M1 cells treated with: a) oxybenzone and b) methylparaben. The results are given as mean % of live cells vs negative control (untreated cells) and denote means with standard deviations of six replicates from two individual experiments. Cells treated with 10 % (v/v) DMSO served as positive control

Figure 3

Androgenic activity of a) oxybenzone and b) methylparaben in the AR-EcoScreen GR KO M1 cell line. The results are given as mean % of inhibition vs positive control (500 pmol/L dihydrotestosterone) and denote means with standard deviations (error bars) of six replicates from two individual experiments. Standard deviations are given as error bars

Figure 4

Anti-androgenic activity of a) oxybenzone and b) methylparaben in the AR-EcoScreen GR KO M1 cell line. The results are given as mean % of inhibition vs positive control (500 pmol/L dihydrotestosterone) and denote means with standard deviations (error bars) of six replicates from two individual experiments. Standard deviations are given as error bars

Figure 5

Estrogenic activity of a) oxybenzone and b) methylparaben in HeLa-9903 cells. The results are given as mean % of inhibition vs positive control (1 nmol/L 17 β-oestradiol) and denote means with standard deviations (error bars) of six replicates from two individual experiments. Standard deviations are given as error bars
DOI: https://doi.org/10.2478/aiht-2025-76-3964 | Journal eISSN: 1848-6312 | Journal ISSN: 0004-1254
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Language: English, Croatian, Slovenian
Page range: 53 - 59
Submitted on: Feb 1, 2025
Accepted on: Mar 1, 2025
Published on: Mar 31, 2025
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
agonist,
antagonist,
AR-EcoScreen GR KO M1,
endocrine disruption,
HeLa-9903,
hormone receptors,
personal care products
Related subjects:
Medicine,
Basic medical science,
Basic medical science, other

© 2025 Nikolina Peranić, Lucija Božičević, Ivana Vinković Vrček, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 76 (2025): Issue 1 (March 2025)
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