Figure 1

Figure 2

Figure 3

Nicotine, cotinine, and trans-3′-hydroxycotinine concentrations in urine samples of 22 study participants before (baseline) and after having spent 190 min in a nightclub and slept for six hours in average (post-exposure)
| Variable | Baseline concentrations (ng/mL) | Post-exposure concentrations (ng/mL) | Differences between baseline and post-exposure measurements* | |||||
|---|---|---|---|---|---|---|---|---|
| Min | Max | Median (IQR) | Min | Max | Median (IQR) | |||
| Smokers (N=5) | Nicotine | 0.66 | 323.34 | 16.22 (172.21) | 25.20 | 509.58 | 364.72 (370.88) | p<0.05 |
| Cotinine | 2.61 | 323.15 | 54.44 (235.22) | 54.82 | 946.04 | 373.06 (639.29) | p=0.095 | |
| 3HC | 5.46 | 451.51 | 168.41 (328.16) | <LOD | 5933.42 | 575.15 (3681.79) | p=0.529 | |
| Non-smokers (N=17) | Nicotine | 0.67 | 42.25 | 2.66 (14.26) | 6.91 | 588.27 | 32.37 (49.29) | p<0.05 |
| Cotinine | <LOD | 63.00 | 35.36 (40.49) | 2.62 | 190.55 | 65.09 (66.94) | p<0.05 | |
| 3HC | 1.23 | 77.76 | 5.46 (16.52) | 2.46 | 148.77 | 32.95 (68.96) | p<0.05 | |