Summary of studies investigating antibiotic resistance of S_ maltophilia
| Authors | Year | Antibiotic resistance findings |
|---|---|---|
| Rahmati-Bahram et al. [81] | 1996 | Investigated temperature-dependent aminoglycoside resistance in S. maltophilia, highlighting alterations in protein and lipopolysaccharide with growth temperature. |
| Avison et al. [76] | 2000 | Identified a TEM-2β-lactamase encoded on an active transposon in the genome of a clinical isolate of S. maltophilia. |
| Barbier-Frebour et al. [77] | 2000 | Explored the molecular mechanisms behind the rapid emergence of ticarcillin-clavulanate resistance in S. maltophilia isolates. |
| Zhang et al. [79] | 2000 | Involvement of a multidrug efflux system in multiple antibiotic resistance in S. maltophilia. |
| Alonso and Martínez [75] | 2000 | Cloning and characterization of SmeDEF, a multidrug efflux pump from S. maltophilia |
| Avison et al. [70] | 2001 | Plasmid location and molecular heterogeneity of beta-lactamase genes of S. maltophilia. |
| Poole [74] | 2004 | Efflux-mediated multiresistance in Gram-negative (G−) bacteria, including mechanisms in S. maltophilia. |
| Gülmez and Hasçelik [71] | 2005 | Antimicrobial resistance and molecular typing of S. maltophilia in a Turkish university hospital |
| Toleman et al. [78] | 2007 | Global emergence of trimethoprim/sulfamethoxazole resistance mediated by acquisition of sul genes in S. maltophilia. |
| Valenza et al. [80] | 2008 | Prevalence and antimicrobial susceptibility of microorganisms, including S. maltophilia, isolated from patients with cystic fibrosis. |
| Liaw et al. [72] | 2010 | Multidrug resistance in clinical isolates of S. maltophilia, including roles of integrons, efflux pumps, and biofilm formation. |
| Al Johani et al. [69] | 2010 | Prevalence of antimicrobial resistance among G− isolates in an adult intensive care unit, including S. maltophilia. |
| Hu et al. [82] | 2011 | S. maltophilia resistance to trimethoprim/sulfamethoxazole mediated by acquisition of sul and dfrA genes in a plasmid-mediated class 1 integron. |