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Comparison of the effects of orbital decompression in Graves' ophthalmopathy

Open Access
|Jan 2024

Figures & Tables

Summary of studies on fat removal decompression (mean reduction of the proptosis: 5_45 mm; 4_1% new onset of diplopia; mean age: 40 yrs_, 2447 people)

Author, country, yearProcedurePatients (N)Follow up (months)Proptosis difference after surgery (mm)Newly developed diplopia (%)Newly developed diplopia (N)
Cheng AM et al., Taiwan, 2017 [33]Fat removal decompression84537.9 ± 24.44.1 ± 1.3323
Wu CH et al., Taiwan, 2007 [24]Fat removal decompression12010.9 ± 5.13.6 ± 1.02.83
Wu W et al., China, 2015 [32]Fat removal decompression10816 ± 4.28.2 ± 1.81.92
Richter DF et al., Germany, 2007 [20]Fat removal decompression1374325.98.638

Summary of studies on lateral orbital wall decompression (mean reduction of the proptosis 4_075 mm; 3_73% new onset diplopia; mean age: 46 yrs_, 264 people)

Author, country, yearProcedurePatients (N)Follow up (months)Proptosis difference after surgery (mm)Newly developed diplopia (%)Newly developed diplopia (N)
Ueland HO et al., Norway, 2016 [78]Lateral wall decompression841243.6 ± 2.15%4
Sellari-Franceschini S et al., Italy, 2010 [48]Lateral wall decompression3964.5 ± 1.983
Chang EL and Piva AP. USA, 2008 [26]Lateral wall decompression3334.5131
Gong Y et al., China, 2018 [79]Lateral wall decompression3834.18 ± 1.1100
Bengoa-González Á et al., United Kingdom, 2019 [60]Lateral wall decompression3564.9 ± 1.5400
Liao SL et al., Taiwan, 2006 [59]Lateral wall decompression359.5 ± 1.73.8 ± 0.915.72

Summary of studies on medial and inferior orbital walls decompression (mean reduction of the proptosis 3_6 mm; 30_5% new onset diplopia; mean age: 50_2 yrs_, 682 people)

Author, country, yearProcedurePatients (N)Follow up (months)Proptosis difference after surgery (mm)Newly developed diplopia (%)Newly developed diplopia (N)
Tallstedt L et al., Sweden, 2000 [87]Medial-inferior decompression6363.25122
Garrity JA et al., USA, 1993 [34]Medial-inferior decompression4288.7 years4.76474
She YY et al., Taiwan, 2012 [80]Medial-inferior decompression2532.07 ± 0.2941
Lund VJ et al., United Kingdom, 1997 [86]Medial-inferior decompression2055.33.8204
Jernfors M et al., Finland, 2007 [85]Medial-inferior decompression785.2 years4.57.76
Liao SL et al., Taiwan, 2001 [90]Medial-inferior decompression68124.42110

Summary of mean proptosis reduction and mean new onset diplopia after decompression of fat or bone reduction

Decompression techinqueProptosis reduction [mm]New onset diplopia [%]
Fat decompression5.44.1
Lateral wall decompression4.33.7
Medial - Lateral wall decompression4.918
Medial - Inferior - Lateral wall decompression4.615
Medial – Inferior decompression3.828

Summary of studies on medial and lateral orbital walls decompression (balanced technique) (mean reduction of the proptosis 4_9 mm; 17% new onset diplopia; mean age: 50 yrs_, 455 people)

Author, country, yearProcedurePatients (N)Follow up (months)Proptosis difference after surgery (mm)Newly developed diplopia (%)Newly developed diplopia (N)
Graham SM et al., USA, 2003 [44]Medial and lateral wall decompression (balanced)4031.54.1104
Dubin MR et al., USA, 2008 [82]Medial and lateral wall decompression (balanced)246 weeks6.229.2 %7
Stähr K et al., Germany, 2018 [83]Medial and lateral wall decompression (balanced)17484.9516%28
Hernández-García E et al., Spain, 2017 [89]Medial and lateral wall decompression (balanced)20443.515%3
Rocchi R et al., Italy, 2012 [84]Medial and lateral wall decompression (balanced)19735.7 ± 2.21819

Summary of studies on 3-wall (medial, inferior, lateral) orbital walls decompression (mean reduction of the proptosis 5_6 mm; 9_2% new onset diplopia; mean age: 46_9 yrs_, 238 people)

Author, country, yearProcedurePatients (N)Follow up (months)Proptosis difference after surgery (mm)Newly developed diplopia (%)Newly developed diplopia (N)
Paridaens DA et al., Netherlands, 2000 [51]Three wall decompression1995.5172
Kingdom TT et al., USA, 2015 [81]Three wall decompression7731.33.200
Bailey KL et al., USA, 2005 [43]Three wall decompression551151.81
Baldeschi L et al., Netherlands, 2005 [10]Three wall decompression1564.9335
Baldeschi L et al., USA, 2006 [88]Three wall decompression12564.32227
Language: English
Page range: 154 - 162
Submitted on: May 7, 2023
Accepted on: Oct 16, 2023
Published on: Jan 11, 2024
Published by: Hirszfeld Institute of Immunology and Experimental Therapy
In partnership with: Paradigm Publishing Services
Publication frequency: 1 times per year

© 2024 Wojciech Skrzypczak, Łukasz Słowik, Maciej Okła, Zuzanna Ślebioda, Krzysztof Osmola, published by Hirszfeld Institute of Immunology and Experimental Therapy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.