Summary of studies on fat removal decompression (mean reduction of the proptosis: 5_45 mm; 4_1% new onset of diplopia; mean age: 40 yrs_, 2447 people)
| Author, country, year | Procedure | Patients (N) | Follow up (months) | Proptosis difference after surgery (mm) | Newly developed diplopia (%) | Newly developed diplopia (N) | 
|---|---|---|---|---|---|---|
| Cheng AM et al., Taiwan, 2017 [33] | Fat removal decompression | 845 | 37.9 ± 24.4 | 4.1 ± 1.3 | 3 | 23 | 
| Wu CH et al., Taiwan, 2007 [24] | Fat removal decompression | 120 | 10.9 ± 5.1 | 3.6 ± 1.0 | 2.8 | 3 | 
| Wu W et al., China, 2015 [32] | Fat removal decompression | 108 | 16 ± 4.2 | 8.2 ± 1.8 | 1.9 | 2 | 
| Richter DF et al., Germany, 2007 [20] | Fat removal decompression | 1374 | 32 | 5.9 | 8.6 | 38 | 
Summary of studies on lateral orbital wall decompression (mean reduction of the proptosis 4_075 mm; 3_73% new onset diplopia; mean age: 46 yrs_, 264 people)
| Author, country, year | Procedure | Patients (N) | Follow up (months) | Proptosis difference after surgery (mm) | Newly developed diplopia (%) | Newly developed diplopia (N) | 
|---|---|---|---|---|---|---|
| Ueland HO et al., Norway, 2016 [78] | Lateral wall decompression | 84 | 124 | 3.6 ± 2.1 | 5% | 4 | 
| Sellari-Franceschini S et al., Italy, 2010 [48] | Lateral wall decompression | 39 | 6 | 4.5 ± 1.9 | 8 | 3 | 
| Chang EL and Piva AP. USA, 2008 [26] | Lateral wall decompression | 33 | 3 | 4.51 | 3 | 1 | 
| Gong Y et al., China, 2018 [79] | Lateral wall decompression | 38 | 3 | 4.18 ± 1.11 | 0 | 0 | 
| Bengoa-González Á et al., United Kingdom, 2019 [60] | Lateral wall decompression | 35 | 6 | 4.9 ± 1.54 | 0 | 0 | 
| Liao SL et al., Taiwan, 2006 [59] | Lateral wall decompression | 35 | 9.5 ± 1.7 | 3.8 ± 0.91 | 5.7 | 2 | 
Summary of studies on medial and inferior orbital walls decompression (mean reduction of the proptosis 3_6 mm; 30_5% new onset diplopia; mean age: 50_2 yrs_, 682 people)
| Author, country, year | Procedure | Patients (N) | Follow up (months) | Proptosis difference after surgery (mm) | Newly developed diplopia (%) | Newly developed diplopia (N) | 
|---|---|---|---|---|---|---|
| Tallstedt L et al., Sweden, 2000 [87] | Medial-inferior decompression | 63 | 6 | 3.2 | 51 | 22 | 
| Garrity JA et al., USA, 1993 [34] | Medial-inferior decompression | 428 | 8.7 years | 4.7 | 64 | 74 | 
| She YY et al., Taiwan, 2012 [80] | Medial-inferior decompression | 25 | 3 | 2.07 ± 0.29 | 4 | 1 | 
| Lund VJ et al., United Kingdom, 1997 [86] | Medial-inferior decompression | 20 | 55.3 | 3.8 | 20 | 4 | 
| Jernfors M et al., Finland, 2007 [85] | Medial-inferior decompression | 78 | 5.2 years | 4.5 | 7.7 | 6 | 
| Liao SL et al., Taiwan, 2001 [90] | Medial-inferior decompression | 68 | 12 | 4.4 | 21 | 10 | 
Summary of mean proptosis reduction and mean new onset diplopia after decompression of fat or bone reduction
| Decompression techinque | Proptosis reduction [mm] | New onset diplopia [%] | 
|---|---|---|
| Fat decompression | 5.4 | 4.1 | 
| Lateral wall decompression | 4.3 | 3.7 | 
| Medial - Lateral wall decompression | 4.9 | 18 | 
| Medial - Inferior - Lateral wall decompression | 4.6 | 15 | 
| Medial – Inferior decompression | 3.8 | 28 | 
Summary of studies on medial and lateral orbital walls decompression (balanced technique) (mean reduction of the proptosis 4_9 mm; 17% new onset diplopia; mean age: 50 yrs_, 455 people)
| Author, country, year | Procedure | Patients (N) | Follow up (months) | Proptosis difference after surgery (mm) | Newly developed diplopia (%) | Newly developed diplopia (N) | 
|---|---|---|---|---|---|---|
| Graham SM et al., USA, 2003 [44] | Medial and lateral wall decompression (balanced) | 40 | 31.5 | 4.1 | 10 | 4 | 
| Dubin MR et al., USA, 2008 [82] | Medial and lateral wall decompression (balanced) | 24 | 6 weeks | 6.2 | 29.2 % | 7 | 
| Stähr K et al., Germany, 2018 [83] | Medial and lateral wall decompression (balanced) | 174 | 8 | 4.95 | 16% | 28 | 
| Hernández-García E et al., Spain, 2017 [89] | Medial and lateral wall decompression (balanced) | 20 | 44 | 3.5 | 15% | 3 | 
| Rocchi R et al., Italy, 2012 [84] | Medial and lateral wall decompression (balanced) | 197 | 3 | 5.7 ± 2.2 | 18 | 19 | 
Summary of studies on 3-wall (medial, inferior, lateral) orbital walls decompression (mean reduction of the proptosis 5_6 mm; 9_2% new onset diplopia; mean age: 46_9 yrs_, 238 people)
| Author, country, year | Procedure | Patients (N) | Follow up (months) | Proptosis difference after surgery (mm) | Newly developed diplopia (%) | Newly developed diplopia (N) | 
|---|---|---|---|---|---|---|
| Paridaens DA et al., Netherlands, 2000 [51] | Three wall decompression | 19 | 9 | 5.5 | 17 | 2 | 
| Kingdom TT et al., USA, 2015 [81] | Three wall decompression | 77 | 31.3 | 3.2 | 0 | 0 | 
| Bailey KL et al., USA, 2005 [43] | Three wall decompression | 55 | 11 | 5 | 1.8 | 1 | 
| Baldeschi L et al., Netherlands, 2005 [10] | Three wall decompression | 15 | 6 | 4.9 | 33 | 5 | 
| Baldeschi L et al., USA, 2006 [88] | Three wall decompression | 125 | 6 | 4.3 | 22 | 27 |